PhosphoNET

           
Protein Info 
   
Short Name:  K10
Full Name:  Keratin, type I cytoskeletal 10
Alias:  CK10; Cytokeratin 10; Cytokeratin-10; Epidermolytic hyperkeratosis; K1C10; Keratin 10; Keratin-10; KPP; KRT10, CK-10
Type:  Cytoskeletal protein
Mass (Da):  58827
Number AA:  584
UniProt ID:  P13645
International Prot ID:  IPI00009865
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005882     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0030280   PhosphoSite+ KinaseNET
Biological Process:  GO:0008544     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSVRYSSSK
Site 2S6__MSVRYSSSKHYSS
Site 3S7_MSVRYSSSKHYSSS
Site 4S8MSVRYSSSKHYSSSR
Site 5Y11RYSSSKHYSSSRSGG
Site 6S12YSSSKHYSSSRSGGG
Site 7S13SSSKHYSSSRSGGGG
Site 8S14SSKHYSSSRSGGGGG
Site 9S16KHYSSSRSGGGGGGG
Site 10S32CGGGGGVSSLRISSS
Site 11S33GGGGGVSSLRISSSK
Site 12S37GVSSLRISSSKGSLG
Site 13S38VSSLRISSSKGSLGG
Site 14S39SSLRISSSKGSLGGG
Site 15S42RISSSKGSLGGGFSS
Site 16S48GSLGGGFSSGGFSGG
Site 17S49SLGGGFSSGGFSGGS
Site 18S53GFSSGGFSGGSFSRG
Site 19S56SGGFSGGSFSRGSSG
Site 20S58GFSGGSFSRGSSGGG
Site 21S61GGSFSRGSSGGGCFG
Site 22S62GSFSRGSSGGGCFGG
Site 23S84LGGFGGGSFRGSYGS
Site 24S88GGGSFRGSYGSSSFG
Site 25Y89GGSFRGSYGSSSFGG
Site 26S91SFRGSYGSSSFGGSY
Site 27S92FRGSYGSSSFGGSYG
Site 28S93RGSYGSSSFGGSYGG
Site 29S97GSSSFGGSYGGIFGG
Site 30Y98SSSFGGSYGGIFGGG
Site 31S111GGSFGGGSFGGGSFG
Site 32S143GGDGGLLSGNEKVTM
Site 33S159NLNDRLASYLDKVRA
Site 34Y160LNDRLASYLDKVRAL
Site 35S170KVRALEESNYELEGK
Site 36Y172RALEESNYELEGKIK
Site 37Y182EGKIKEWYEKHGNSH
Site 38Y196HQGEPRDYSKYYKTI
Site 39S197QGEPRDYSKYYKTID
Site 40Y199EPRDYSKYYKTIDDL
Site 41Y200PRDYSKYYKTIDDLK
Site 42Y238ADDFRLKYENEVALR
Site 43S247NEVALRQSVEADING
Site 44T263RRVLDELTLTKADLE
Site 45T265VLDELTLTKADLEMQ
Site 46S275DLEMQIESLTEELAY
Site 47Y282SLTEELAYLKKNHEE
Site 48S298MKDLRNVSTGDVNVE
Site 49T315AAPGVDLTQLLNNMR
Site 50S323QLLNNMRSQYEQLAE
Site 51Y325LNNMRSQYEQLAEQN
Site 52S344EAWFNEKSKELTTEI
Site 53T348NEKSKELTTEIDNNI
Site 54S359DNNIEQISSYKSEIT
Site 55S360NNIEQISSYKSEITE
Site 56S363EQISSYKSEITELRR
Site 57S388SQLALKQSLEASLAE
Site 58S392LKQSLEASLAETEGR
Site 59T396LEASLAETEGRYCVQ
Site 60S405GRYCVQLSQIQAQIS
Site 61T425LQQIRAETECQNTEY
Site 62T430AETECQNTEYQQLLD
Site 63Y432TECQNTEYQQLLDIK
Site 64Y449LENEIQTYRSLLEGE
Site 65S451NEIQTYRSLLEGEGS
Site 66S458SLLEGEGSSGGGGRG
Site 67S459LLEGEGSSGGGGRGG
Site 68S468GGGRGGGSFGGGYGG
Site 69Y473GGSFGGGYGGGSSGG
Site 70S477GGGYGGGSSGGGSSG
Site 71S478GGYGGGSSGGGSSGG
Site 72Y487GGSSGGGYGGGHGGS
Site 73S494YGGGHGGSSGGGYGG
Site 74S495GGGHGGSSGGGYGGG
Site 75Y499GGSSGGGYGGGSSGG
Site 76S508GGSSGGGSSGGGYGG
Site 77S509GSSGGGSSGGGYGGG
Site 78Y513GGSSGGGYGGGSSSG
Site 79S517GGGYGGGSSSGGHGG
Site 80S518GGYGGGSSSGGHGGS
Site 81S519GYGGGSSSGGHGGSS
Site 82S525SSGGHGGSSSGGYGG
Site 83S526SGGHGGSSSGGYGGG
Site 84S527GGHGGSSSGGYGGGS
Site 85Y530GGSSSGGYGGGSSGG
Site 86S534SGGYGGGSSGGGGGG
Site 87S535GGYGGGSSGGGGGGY
Site 88Y542SGGGGGGYGGGSSGG
Site 89S546GGGYGGGSSGGGSSS
Site 90S547GGYGGGSSGGGSSSG
Site 91S551GGSSGGGSSSGGGYG
Site 92S552GSSGGGSSSGGGYGG
Site 93S553SSGGGSSSGGGYGGG
Site 94Y557GSSSGGGYGGGSSSG
Site 95S561GGGYGGGSSSGGHKS
Site 96S562GGYGGGSSSGGHKSS
Site 97S563GYGGGSSSGGHKSSS
Site 98S568SSSGGHKSSSSGSVG
Site 99S569SSGGHKSSSSGSVGE
Site 100S570SGGHKSSSSGSVGES
Site 101S571GGHKSSSSGSVGESS
Site 102S573HKSSSSGSVGESSSK
Site 103S577SSGSVGESSSKGPRY
Site 104S578SGSVGESSSKGPRY_
Site 105S579GSVGESSSKGPRY__
Site 106Y584SSSKGPRY_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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