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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BMP4
Full Name:
Bone morphogenetic protein 4
Alias:
Bone morphogenetic protein 2B
Type:
Mass (Da):
46555
Number AA:
408
UniProt ID:
P12644
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
L
G
G
A
S
H
A
S
L
I
P
E
T
G
K
Site 2
S47
G
H
A
G
G
R
R
S
G
Q
S
H
E
L
L
Site 3
S50
G
G
R
R
S
G
Q
S
H
E
L
L
R
D
F
Site 4
S74
L
R
R
R
P
Q
P
S
K
S
A
V
I
P
D
Site 5
S76
R
R
P
Q
P
S
K
S
A
V
I
P
D
Y
M
Site 6
Y82
K
S
A
V
I
P
D
Y
M
R
D
L
Y
R
L
Site 7
Y87
P
D
Y
M
R
D
L
Y
R
L
Q
S
G
E
E
Site 8
S91
R
D
L
Y
R
L
Q
S
G
E
E
E
E
E
Q
Site 9
S101
E
E
E
E
Q
I
H
S
T
G
L
E
Y
P
E
Site 10
Y106
I
H
S
T
G
L
E
Y
P
E
R
P
A
S
R
Site 11
S112
E
Y
P
E
R
P
A
S
R
A
N
T
V
R
S
Site 12
T116
R
P
A
S
R
A
N
T
V
R
S
F
H
H
E
Site 13
S119
S
R
A
N
T
V
R
S
F
H
H
E
E
H
L
Site 14
T132
H
L
E
N
I
P
G
T
S
E
N
S
A
F
R
Site 15
S136
I
P
G
T
S
E
N
S
A
F
R
F
L
F
N
Site 16
S155
P
E
N
E
V
I
S
S
A
E
L
R
L
F
R
Site 17
Y181
G
F
H
R
I
N
I
Y
E
V
M
K
P
P
A
Site 18
T214
H
N
V
T
R
W
E
T
F
D
V
S
P
A
V
Site 19
S218
R
W
E
T
F
D
V
S
P
A
V
L
R
W
T
Site 20
T225
S
P
A
V
L
R
W
T
R
E
K
Q
P
N
Y
Site 21
S255
Q
G
Q
H
V
R
I
S
R
S
L
P
Q
G
S
Site 22
S257
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
N
Site 23
T274
Q
L
R
P
L
L
V
T
F
G
H
D
G
R
G
Site 24
T285
D
G
R
G
H
A
L
T
R
R
R
R
A
K
R
Site 25
S293
R
R
R
R
A
K
R
S
P
K
H
H
S
Q
R
Site 26
S298
K
R
S
P
K
H
H
S
Q
R
A
R
K
K
N
Site 27
S312
N
K
N
C
R
R
H
S
L
Y
V
D
F
S
D
Site 28
Y314
N
C
R
R
H
S
L
Y
V
D
F
S
D
V
G
Site 29
Y389
S
M
L
Y
L
D
E
Y
D
K
V
V
L
K
N
Site 30
Y397
D
K
V
V
L
K
N
Y
Q
E
M
V
V
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation