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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CKMT1A
Full Name:
Creatine kinase U-type, mitochondrial
Alias:
Acidic-type mitochondrial creatine kinase; CKMT1B; EC 2.7.3.2; KCRU; Mia-CK; U-MtCK
Type:
Enzyme - Metabolite kinase; Membrane, mitochondrial inner membrane, mitochondria
Mass (Da):
47037
Number AA:
417
UniProt ID:
P12532
International Prot ID:
IPI00658109
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005743
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004111
PhosphoSite+
KinaseNET
Biological Process:
GO:0003008
GO:0003012
GO:0006082
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
G
P
F
S
R
L
L
S
A
R
P
Site 2
S10
G
P
F
S
R
L
L
S
A
R
P
G
L
R
L
Site 3
S41
P
E
P
V
R
A
A
S
E
R
R
R
L
Y
P
Site 4
Y47
A
S
E
R
R
R
L
Y
P
P
S
A
E
Y
P
Site 5
S50
R
R
R
L
Y
P
P
S
A
E
Y
P
D
L
R
Site 6
Y53
L
Y
P
P
S
A
E
Y
P
D
L
R
K
H
N
Site 7
Y72
S
H
L
T
P
A
V
Y
A
R
L
C
D
K
T
Site 8
T79
Y
A
R
L
C
D
K
T
T
P
T
G
W
T
L
Site 9
T80
A
R
L
C
D
K
T
T
P
T
G
W
T
L
D
Site 10
T82
L
C
D
K
T
T
P
T
G
W
T
L
D
Q
C
Site 11
T85
K
T
T
P
T
G
W
T
L
D
Q
C
I
Q
T
Site 12
Y133
I
Q
E
R
H
N
G
Y
D
P
R
T
M
K
H
Site 13
T137
H
N
G
Y
D
P
R
T
M
K
H
T
T
D
L
Site 14
T141
D
P
R
T
M
K
H
T
T
D
L
D
A
S
K
Site 15
S147
H
T
T
D
L
D
A
S
K
I
R
S
G
Y
F
Site 16
S151
L
D
A
S
K
I
R
S
G
Y
F
D
E
R
Y
Site 17
Y153
A
S
K
I
R
S
G
Y
F
D
E
R
Y
V
L
Site 18
Y158
S
G
Y
F
D
E
R
Y
V
L
S
S
R
V
R
Site 19
S161
F
D
E
R
Y
V
L
S
S
R
V
R
T
G
R
Site 20
S162
D
E
R
Y
V
L
S
S
R
V
R
T
G
R
S
Site 21
T166
V
L
S
S
R
V
R
T
G
R
S
I
R
G
L
Site 22
S169
S
R
V
R
T
G
R
S
I
R
G
L
S
L
P
Site 23
S174
G
R
S
I
R
G
L
S
L
P
P
A
C
T
R
Site 24
S196
R
V
V
V
D
A
L
S
G
L
K
G
D
L
A
Site 25
Y206
K
G
D
L
A
G
R
Y
Y
R
L
S
E
M
T
Site 26
Y207
G
D
L
A
G
R
Y
Y
R
L
S
E
M
T
E
Site 27
S210
A
G
R
Y
Y
R
L
S
E
M
T
E
A
E
Q
Site 28
S232
F
L
F
D
K
P
V
S
P
L
L
T
A
A
G
Site 29
T236
K
P
V
S
P
L
L
T
A
A
G
M
A
R
D
Site 30
T268
W
V
N
E
E
D
H
T
R
V
I
S
M
E
K
Site 31
S272
E
D
H
T
R
V
I
S
M
E
K
G
G
N
M
Site 32
Y312
M
W
N
E
R
L
G
Y
I
L
T
C
P
S
N
Site 33
T315
E
R
L
G
Y
I
L
T
C
P
S
N
L
G
T
Site 34
S318
G
Y
I
L
T
C
P
S
N
L
G
T
G
L
R
Site 35
T322
T
C
P
S
N
L
G
T
G
L
R
A
G
V
H
Site 36
S336
H
I
K
L
P
L
L
S
K
D
S
R
F
P
K
Site 37
S339
L
P
L
L
S
K
D
S
R
F
P
K
I
L
E
Site 38
T355
L
R
L
Q
K
R
G
T
G
G
V
D
T
A
A
Site 39
S370
T
G
G
V
F
D
I
S
N
L
D
R
L
G
K
Site 40
S378
N
L
D
R
L
G
K
S
E
V
E
L
V
Q
L
Site 41
T410
G
Q
D
I
R
I
P
T
P
V
I
H
T
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation