PhosphoNET

           
Protein Info 
   
Short Name:  PTHrP
Full Name:  Parathyroid hormone-related protein
Alias:  HHM; Osteostatin; Parathyroid hormone-like hormone; PLP; PTHLH; PTHR; PTHRP; PTH-rP; PTHrP[107-139]
Type:  Secreted protein
Mass (Da):  20190
Number AA:  177
UniProt ID:  P12272
International Prot ID:  IPI00414875
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005615  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005179   PhosphoSite+ KinaseNET
Biological Process:  GO:0007189  GO:0046058  GO:0007267 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S26AVPSCGRSVEGLSRR
Site 2S31GRSVEGLSRRLKRAV
Site 3S39RRLKRAVSEHQLLHD
Site 4S50LLHDKGKSIQDLRRR
Site 5T75HTAEIRATSEVSPNS
Site 6S76TAEIRATSEVSPNSK
Site 7S79IRATSEVSPNSKPSP
Site 8S82TSEVSPNSKPSPNTK
Site 9S85VSPNSKPSPNTKNHP
Site 10S97NHPVRFGSDDEGRYL
Site 11Y103GSDDEGRYLTQETNK
Site 12T105DDEGRYLTQETNKVE
Site 13T108GRYLTQETNKVETYK
Site 14T113QETNKVETYKEQPLK
Site 15T121YKEQPLKTPGKKKKG
Site 16T143QEKKKRRTRSAWLDS
Site 17S145KKKRRTRSAWLDSGV
Site 18S150TRSAWLDSGVTGSGL
Site 19S155LDSGVTGSGLEGDHL
Site 20S163GLEGDHLSDTSTTSL
Site 21T165EGDHLSDTSTTSLEL
Site 22S166GDHLSDTSTTSLELD
Site 23T167DHLSDTSTTSLELDS
Site 24S169LSDTSTTSLELDSRR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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