KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DMD
Full Name:
Dystrophin
Alias:
BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; Dystrophin (Muscular dystrophy, Duchenne and Becker types); Muscular dystrophy, Duchenne and Becker types
Type:
Cytoskeletal protein
Mass (Da):
426692
Number AA:
3685
UniProt ID:
P11532
International Prot ID:
IPI00304638
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0043034
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005509
GO:0050998
PhosphoSite+
KinaseNET
Biological Process:
GO:0043043
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
W
E
E
V
E
D
C
Y
E
R
E
D
V
Q
K
Site 2
T20
R
E
D
V
Q
K
K
T
F
T
K
W
V
N
A
Site 3
S42
Q
H
I
E
N
L
F
S
D
L
Q
D
G
R
R
Site 4
S68
K
L
P
K
E
K
G
S
T
R
V
H
A
L
N
Site 5
S136
A
G
L
Q
Q
T
N
S
E
K
I
L
L
S
W
Site 6
S142
N
S
E
K
I
L
L
S
W
V
R
Q
S
T
R
Site 7
S147
L
L
S
W
V
R
Q
S
T
R
N
Y
P
Q
V
Site 8
T148
L
S
W
V
R
Q
S
T
R
N
Y
P
Q
V
N
Site 9
Y151
V
R
Q
S
T
R
N
Y
P
Q
V
N
V
I
N
Site 10
T160
Q
V
N
V
I
N
F
T
T
S
W
S
D
G
L
Site 11
S175
A
L
N
A
L
I
H
S
H
R
P
D
L
F
D
Site 12
T193
V
V
C
Q
Q
S
A
T
Q
R
L
E
H
A
F
Site 13
T220
L
D
P
E
D
V
D
T
T
Y
P
D
K
K
S
Site 14
T221
D
P
E
D
V
D
T
T
Y
P
D
K
K
S
I
Site 15
Y222
P
E
D
V
D
T
T
Y
P
D
K
K
S
I
L
Site 16
S227
T
T
Y
P
D
K
K
S
I
L
M
Y
I
T
S
Site 17
T261
L
P
R
P
P
K
V
T
K
E
E
H
F
Q
L
Site 18
T279
M
H
Y
S
Q
Q
I
T
V
S
L
A
Q
G
Y
Site 19
S281
Y
S
Q
Q
I
T
V
S
L
A
Q
G
Y
E
R
Site 20
Y286
T
V
S
L
A
Q
G
Y
E
R
T
S
S
P
K
Site 21
T289
L
A
Q
G
Y
E
R
T
S
S
P
K
P
R
F
Site 22
S290
A
Q
G
Y
E
R
T
S
S
P
K
P
R
F
K
Site 23
S291
Q
G
Y
E
R
T
S
S
P
K
P
R
F
K
S
Site 24
S298
S
P
K
P
R
F
K
S
Y
A
Y
T
Q
A
A
Site 25
T302
R
F
K
S
Y
A
Y
T
Q
A
A
Y
V
T
T
Site 26
Y306
Y
A
Y
T
Q
A
A
Y
V
T
T
S
D
P
T
Site 27
S310
Q
A
A
Y
V
T
T
S
D
P
T
R
S
P
F
Site 28
T313
Y
V
T
T
S
D
P
T
R
S
P
F
P
S
Q
Site 29
S315
T
T
S
D
P
T
R
S
P
F
P
S
Q
H
L
Site 30
S319
P
T
R
S
P
F
P
S
Q
H
L
E
A
P
E
Site 31
S329
L
E
A
P
E
D
K
S
F
G
S
S
L
M
E
Site 32
S332
P
E
D
K
S
F
G
S
S
L
M
E
S
E
V
Site 33
S333
E
D
K
S
F
G
S
S
L
M
E
S
E
V
N
Site 34
S337
F
G
S
S
L
M
E
S
E
V
N
L
D
R
Y
Site 35
Y344
S
E
V
N
L
D
R
Y
Q
T
A
L
E
E
V
Site 36
T346
V
N
L
D
R
Y
Q
T
A
L
E
E
V
L
S
Site 37
T361
W
L
L
S
A
E
D
T
L
Q
A
Q
G
E
I
Site 38
S369
L
Q
A
Q
G
E
I
S
N
D
V
E
V
V
K
Site 39
T390
E
G
Y
M
M
D
L
T
A
H
Q
G
R
V
G
Site 40
S413
L
I
G
T
G
K
L
S
E
D
E
E
T
E
V
Site 41
T418
K
L
S
E
D
E
E
T
E
V
Q
E
Q
M
N
Site 42
S438
W
E
C
L
R
V
A
S
M
E
K
Q
S
N
L
Site 43
T465
K
E
L
N
D
W
L
T
K
T
E
E
R
T
R
Site 44
T467
L
N
D
W
L
T
K
T
E
E
R
T
R
K
M
Site 45
T565
L
L
K
W
Q
R
L
T
E
E
Q
C
L
F
S
Site 46
S572
T
E
E
Q
C
L
F
S
A
W
L
S
E
K
E
Site 47
S576
C
L
F
S
A
W
L
S
E
K
E
D
A
V
N
Site 48
S599
D
Q
N
E
M
L
S
S
L
Q
K
L
A
V
L
Site 49
S622
Q
S
M
G
K
L
Y
S
L
K
Q
D
L
L
S
Site 50
S629
S
L
K
Q
D
L
L
S
T
L
K
N
K
S
V
Site 51
T630
L
K
Q
D
L
L
S
T
L
K
N
K
S
V
T
Site 52
S635
L
S
T
L
K
N
K
S
V
T
Q
K
T
E
A
Site 53
S661
L
V
Q
K
L
E
K
S
T
A
Q
I
S
Q
A
Site 54
S666
E
K
S
T
A
Q
I
S
Q
A
V
T
T
T
Q
Site 55
T670
A
Q
I
S
Q
A
V
T
T
T
Q
P
S
L
T
Site 56
T671
Q
I
S
Q
A
V
T
T
T
Q
P
S
L
T
Q
Site 57
T672
I
S
Q
A
V
T
T
T
Q
P
S
L
T
Q
T
Site 58
T679
T
Q
P
S
L
T
Q
T
T
V
M
E
T
V
T
Site 59
T687
T
V
M
E
T
V
T
T
V
T
T
R
E
Q
I
Site 60
T715
P
Q
K
K
R
Q
I
T
V
D
S
E
I
R
K
Site 61
S718
K
R
Q
I
T
V
D
S
E
I
R
K
R
L
D
Site 62
T729
K
R
L
D
V
D
I
T
E
L
H
S
W
I
T
Site 63
S738
L
H
S
W
I
T
R
S
E
A
V
L
Q
S
P
Site 64
S744
R
S
E
A
V
L
Q
S
P
E
F
A
I
F
R
Site 65
S757
F
R
K
E
G
N
F
S
D
L
K
E
K
V
N
Site 66
Y828
E
R
L
N
W
L
E
Y
Q
N
N
I
I
A
F
Site 67
T847
Q
Q
L
E
Q
M
T
T
T
A
E
N
W
L
K
Site 68
T858
N
W
L
K
I
Q
P
T
T
P
S
E
P
T
A
Site 69
T859
W
L
K
I
Q
P
T
T
P
S
E
P
T
A
I
Site 70
S868
S
E
P
T
A
I
K
S
Q
L
K
I
C
K
D
Site 71
S881
K
D
E
V
N
R
L
S
G
L
Q
P
Q
I
E
Site 72
S894
I
E
R
L
K
I
Q
S
I
A
L
K
E
K
G
Site 73
S923
N
H
F
K
Q
V
F
S
D
V
Q
A
R
E
K
Site 74
T938
E
L
Q
T
I
F
D
T
L
P
P
M
R
Y
Q
Site 75
Y944
D
T
L
P
P
M
R
Y
Q
E
T
M
S
A
I
Site 76
T953
E
T
M
S
A
I
R
T
W
V
Q
Q
S
E
T
Site 77
S963
Q
Q
S
E
T
K
L
S
I
P
Q
L
S
V
T
Site 78
T970
S
I
P
Q
L
S
V
T
D
Y
E
I
M
E
Q
Site 79
Y972
P
Q
L
S
V
T
D
Y
E
I
M
E
Q
R
L
Site 80
S987
G
E
L
Q
A
L
Q
S
S
L
Q
E
Q
Q
S
Site 81
S988
E
L
Q
A
L
Q
S
S
L
Q
E
Q
Q
S
G
Site 82
S994
S
S
L
Q
E
Q
Q
S
G
L
Y
Y
L
S
T
Site 83
Y998
E
Q
Q
S
G
L
Y
Y
L
S
T
T
V
K
E
Site 84
S1000
Q
S
G
L
Y
Y
L
S
T
T
V
K
E
M
S
Site 85
T1001
S
G
L
Y
Y
L
S
T
T
V
K
E
M
S
K
Site 86
T1002
G
L
Y
Y
L
S
T
T
V
K
E
M
S
K
K
Site 87
S1015
K
K
A
P
S
E
I
S
R
K
Y
Q
S
E
F
Site 88
Y1018
P
S
E
I
S
R
K
Y
Q
S
E
F
E
E
I
Site 89
S1020
E
I
S
R
K
Y
Q
S
E
F
E
E
I
E
G
Site 90
S1033
E
G
R
W
K
K
L
S
S
Q
L
V
E
H
C
Site 91
S1034
G
R
W
K
K
L
S
S
Q
L
V
E
H
C
Q
Site 92
S1104
D
I
Q
T
I
Q
P
S
L
N
S
V
N
E
G
Site 93
S1107
T
I
Q
P
S
L
N
S
V
N
E
G
G
Q
K
Site 94
T1129
E
F
A
S
R
L
E
T
E
L
K
E
L
N
T
Site 95
Y1146
D
H
M
C
Q
Q
V
Y
A
R
K
E
A
L
K
Site 96
T1159
L
K
G
G
L
E
K
T
V
S
L
Q
K
D
L
Site 97
S1161
G
G
L
E
K
T
V
S
L
Q
K
D
L
S
E
Site 98
Y1180
M
T
Q
A
E
E
E
Y
L
E
R
D
F
E
Y
Site 99
Y1187
Y
L
E
R
D
F
E
Y
K
T
P
D
E
L
Q
Site 100
T1189
E
R
D
F
E
Y
K
T
P
D
E
L
Q
K
A
Site 101
T1260
R
L
N
G
K
C
K
T
L
E
E
V
W
A
C
Site 102
S1273
A
C
W
H
E
L
L
S
Y
L
E
K
A
N
K
Site 103
Y1274
C
W
H
E
L
L
S
Y
L
E
K
A
N
K
W
Site 104
T1291
E
V
E
F
K
L
K
T
T
E
N
I
P
G
G
Site 105
S1303
P
G
G
A
E
E
I
S
E
V
L
D
S
L
E
Site 106
S1308
E
I
S
E
V
L
D
S
L
E
N
L
M
R
H
Site 107
S1316
L
E
N
L
M
R
H
S
E
D
N
P
N
Q
I
Site 108
T1331
R
I
L
A
Q
T
L
T
D
G
G
V
M
D
E
Site 109
T1346
L
I
N
E
E
L
E
T
F
N
S
R
W
R
E
Site 110
S1349
E
E
L
E
T
F
N
S
R
W
R
E
L
H
E
Site 111
T1375
S
I
Q
S
A
Q
E
T
E
K
S
L
H
L
I
Site 112
S1378
S
A
Q
E
T
E
K
S
L
H
L
I
Q
E
S
Site 113
S1385
S
L
H
L
I
Q
E
S
L
T
F
I
D
K
Q
Site 114
S1415
Q
E
A
Q
K
I
Q
S
D
L
T
S
H
E
I
Site 115
S1419
K
I
Q
S
D
L
T
S
H
E
I
S
L
E
E
Site 116
S1423
D
L
T
S
H
E
I
S
L
E
E
M
K
K
H
Site 117
S1442
E
A
A
Q
R
V
L
S
Q
I
D
V
A
Q
K
Site 118
S1455
Q
K
K
L
Q
D
V
S
M
K
F
R
L
F
Q
Site 119
S1492
L
P
A
L
E
T
K
S
V
E
Q
E
V
V
Q
Site 120
Y1509
L
N
H
C
V
N
L
Y
K
S
L
S
E
V
K
Site 121
S1511
H
C
V
N
L
Y
K
S
L
S
E
V
K
S
E
Site 122
S1513
V
N
L
Y
K
S
L
S
E
V
K
S
E
V
E
Site 123
S1517
K
S
L
S
E
V
K
S
E
V
E
M
V
I
K
Site 124
T1525
E
V
E
M
V
I
K
T
G
R
Q
I
V
Q
K
Site 125
T1535
Q
I
V
Q
K
K
Q
T
E
N
P
K
E
L
D
Site 126
T1546
K
E
L
D
E
R
V
T
A
L
K
L
H
Y
N
Site 127
S1573
L
E
K
C
L
K
L
S
R
K
M
R
K
E
M
Site 128
T1590
L
T
E
W
L
A
A
T
D
M
E
L
T
K
R
Site 129
T1595
A
A
T
D
M
E
L
T
K
R
S
A
V
E
G
Site 130
S1605
S
A
V
E
G
M
P
S
N
L
D
S
E
V
A
Site 131
S1609
G
M
P
S
N
L
D
S
E
V
A
W
G
K
A
Site 132
S1630
K
Q
K
V
H
L
K
S
I
T
E
V
G
E
A
Site 133
T1640
E
V
G
E
A
L
K
T
V
L
G
K
K
E
T
Site 134
T1647
T
V
L
G
K
K
E
T
L
V
E
D
K
L
S
Site 135
T1700
K
W
I
I
Q
A
D
T
L
L
D
E
S
E
K
Site 136
S1705
A
D
T
L
L
D
E
S
E
K
K
K
P
Q
Q
Site 137
S1733
D
I
R
P
K
V
D
S
T
R
D
Q
A
A
N
Site 138
S1758
K
L
V
E
P
Q
I
S
E
L
N
H
R
F
A
Site 139
S1768
N
H
R
F
A
A
I
S
H
R
I
K
T
G
K
Site 140
T1773
A
I
S
H
R
I
K
T
G
K
A
S
I
P
L
Site 141
S1788
K
E
L
E
Q
F
N
S
D
I
Q
K
L
L
E
Site 142
T1839
D
N
L
Q
Q
R
I
T
D
E
R
K
R
E
E
Site 143
S1866
N
A
L
K
D
L
R
S
Q
R
R
K
K
A
L
Site 144
Y1880
L
E
I
S
H
Q
W
Y
Q
Y
K
R
Q
A
D
Site 145
Y1882
I
S
H
Q
W
Y
Q
Y
K
R
Q
A
D
D
L
Site 146
S1953
E
P
T
Q
I
Q
L
S
K
R
W
R
E
I
E
Site 147
T1976
L
N
F
A
Q
I
H
T
V
R
E
E
T
M
M
Site 148
T1981
I
H
T
V
R
E
E
T
M
M
V
M
T
E
D
Site 149
S1994
E
D
M
P
L
E
I
S
Y
V
P
S
T
Y
L
Site 150
T2002
Y
V
P
S
T
Y
L
T
E
I
T
H
V
S
Q
Site 151
S2044
S
L
K
N
I
K
D
S
L
Q
Q
S
S
G
R
Site 152
S2048
I
K
D
S
L
Q
Q
S
S
G
R
I
D
I
I
Site 153
S2049
K
D
S
L
Q
Q
S
S
G
R
I
D
I
I
H
Site 154
S2079
V
K
L
Q
E
A
L
S
Q
L
D
F
Q
W
E
Site 155
Y2092
W
E
K
V
N
K
M
Y
K
D
R
Q
G
R
F
Site 156
S2102
R
Q
G
R
F
D
R
S
V
E
K
W
R
R
F
Site 157
T2130
A
E
Q
F
L
R
K
T
Q
I
P
E
N
W
E
Site 158
Y2141
E
N
W
E
H
A
K
Y
K
W
Y
L
K
E
L
Site 159
T2157
D
G
I
G
Q
R
Q
T
V
V
R
T
L
N
A
Site 160
T2165
V
V
R
T
L
N
A
T
G
E
E
I
I
Q
Q
Site 161
T2176
I
I
Q
Q
S
S
K
T
D
A
S
I
L
Q
E
Site 162
S2179
Q
S
S
K
T
D
A
S
I
L
Q
E
K
L
G
Site 163
S2187
I
L
Q
E
K
L
G
S
L
N
L
R
W
Q
E
Site 164
S2200
Q
E
V
C
K
Q
L
S
D
R
K
K
R
L
E
Site 165
S2284
V
L
V
S
A
P
I
S
P
E
E
Q
D
K
L
Site 166
S2306
N
L
Q
W
I
K
V
S
R
A
L
P
E
K
Q
Site 167
S2345
N
H
L
L
L
W
L
S
P
I
R
N
Q
L
E
Site 168
Y2354
I
R
N
Q
L
E
I
Y
N
Q
P
N
Q
E
G
Site 169
S2384
P
D
V
E
E
I
L
S
K
G
Q
H
L
Y
K
Site 170
T2396
L
Y
K
E
K
P
A
T
Q
P
V
K
R
K
L
Site 171
S2407
K
R
K
L
E
D
L
S
S
E
W
K
A
V
N
Site 172
S2408
R
K
L
E
D
L
S
S
E
W
K
A
V
N
R
Site 173
S2457
V
T
K
E
T
A
I
S
K
L
E
M
P
S
S
Site 174
T2480
A
D
F
N
R
A
W
T
E
L
T
D
W
L
S
Site 175
T2483
N
R
A
W
T
E
L
T
D
W
L
S
L
L
D
Site 176
T2532
P
Q
L
E
E
L
I
T
A
A
Q
N
L
K
N
Site 177
S2605
Q
A
R
A
K
L
E
S
W
K
E
G
P
Y
T
Site 178
T2612
S
W
K
E
G
P
Y
T
V
D
A
I
Q
K
K
Site 179
Y2651
A
L
K
L
L
R
D
Y
S
A
D
D
T
R
K
Site 180
S2652
L
K
L
L
R
D
Y
S
A
D
D
T
R
K
V
Site 181
T2656
R
D
Y
S
A
D
D
T
R
K
V
H
M
I
T
Site 182
S2669
I
T
E
N
I
N
A
S
W
R
S
I
H
K
R
Site 183
S2672
N
I
N
A
S
W
R
S
I
H
K
R
V
S
E
Site 184
S2678
R
S
I
H
K
R
V
S
E
R
E
A
A
L
E
Site 185
S2728
K
E
R
L
L
E
D
S
K
G
V
K
E
L
M
Site 186
Y2752
I
E
A
H
T
D
V
Y
H
N
L
D
E
N
S
Site 187
S2759
Y
H
N
L
D
E
N
S
Q
K
I
L
R
S
L
Site 188
S2765
N
S
Q
K
I
L
R
S
L
E
G
S
D
D
A
Site 189
S2787
D
N
M
N
F
K
W
S
E
L
R
K
K
S
L
Site 190
S2793
W
S
E
L
R
K
K
S
L
N
I
R
S
H
L
Site 191
S2798
K
K
S
L
N
I
R
S
H
L
E
A
S
S
D
Site 192
S2804
R
S
H
L
E
A
S
S
D
Q
W
K
R
L
H
Site 193
S2813
Q
W
K
R
L
H
L
S
L
Q
E
L
L
V
W
Site 194
S2829
Q
L
K
D
D
E
L
S
R
Q
A
P
I
G
G
Site 195
T2857
A
F
K
R
E
L
K
T
K
E
P
V
I
M
S
Site 196
T2868
V
I
M
S
T
L
E
T
V
R
I
F
L
T
E
Site 197
Y2885
L
E
G
L
E
K
L
Y
Q
E
P
R
E
L
P
Site 198
T2913
K
Q
A
E
E
V
N
T
E
W
E
K
L
N
L
Site 199
T2932
W
Q
R
K
I
D
E
T
L
E
R
L
Q
E
L
Site 200
S2959
Q
A
E
V
I
K
G
S
W
Q
P
V
G
D
L
Site 201
S2970
V
G
D
L
L
I
D
S
L
Q
D
H
L
E
K
Site 202
S2993
A
P
L
K
E
N
V
S
H
V
N
D
L
A
R
Site 203
T3003
N
D
L
A
R
Q
L
T
T
L
G
I
Q
L
S
Site 204
Y3012
L
G
I
Q
L
S
P
Y
N
L
S
T
L
E
D
Site 205
T3016
L
S
P
Y
N
L
S
T
L
E
D
L
N
T
R
Site 206
T3022
S
T
L
E
D
L
N
T
R
W
K
L
L
Q
V
Site 207
S3049
H
R
D
F
G
P
A
S
Q
H
F
L
S
T
S
Site 208
S3054
P
A
S
Q
H
F
L
S
T
S
V
Q
G
P
W
Site 209
S3056
S
Q
H
F
L
S
T
S
V
Q
G
P
W
E
R
Site 210
S3066
G
P
W
E
R
A
I
S
P
N
K
V
P
Y
Y
Site 211
Y3073
S
P
N
K
V
P
Y
Y
I
N
H
E
T
Q
T
Site 212
Y3092
H
P
K
M
T
E
L
Y
Q
S
L
A
D
L
N
Site 213
S3094
K
M
T
E
L
Y
Q
S
L
A
D
L
N
N
V
Site 214
S3104
D
L
N
N
V
R
F
S
A
Y
R
T
A
M
K
Site 215
T3108
V
R
F
S
A
Y
R
T
A
M
K
L
R
R
L
Site 216
Y3158
I
N
C
L
T
T
I
Y
D
R
L
E
Q
E
H
Site 217
Y3186
L
N
W
L
L
N
V
Y
D
T
G
R
T
G
R
Site 218
T3188
W
L
L
N
V
Y
D
T
G
R
T
G
R
I
R
Site 219
Y3215
K
A
H
L
E
D
K
Y
R
Y
L
F
K
Q
V
Site 220
S3225
L
F
K
Q
V
A
S
S
T
G
F
C
D
Q
R
Site 221
S3253
R
Q
L
G
E
V
A
S
F
G
G
S
N
I
E
Site 222
S3257
E
V
A
S
F
G
G
S
N
I
E
P
S
V
R
Site 223
S3262
G
G
S
N
I
E
P
S
V
R
S
C
F
Q
F
Site 224
S3291
W
M
R
L
E
P
Q
S
M
V
W
L
P
V
L
Site 225
Y3354
A
K
G
H
K
M
H
Y
P
M
V
E
Y
C
T
Site 226
Y3359
M
H
Y
P
M
V
E
Y
C
T
P
T
T
S
G
Site 227
T3361
Y
P
M
V
E
Y
C
T
P
T
T
S
G
E
D
Site 228
T3382
V
L
K
N
K
F
R
T
K
R
Y
F
A
K
H
Site 229
Y3385
N
K
F
R
T
K
R
Y
F
A
K
H
P
R
M
Site 230
Y3394
A
K
H
P
R
M
G
Y
L
P
V
Q
T
V
L
Site 231
T3408
L
E
G
D
N
M
E
T
P
V
T
L
I
N
F
Site 232
S3420
I
N
F
W
P
V
D
S
A
P
A
S
S
P
Q
Site 233
S3424
P
V
D
S
A
P
A
S
S
P
Q
L
S
H
D
Site 234
S3425
V
D
S
A
P
A
S
S
P
Q
L
S
H
D
D
Site 235
S3429
P
A
S
S
P
Q
L
S
H
D
D
T
H
S
R
Site 236
T3433
P
Q
L
S
H
D
D
T
H
S
R
I
E
H
Y
Site 237
S3435
L
S
H
D
D
T
H
S
R
I
E
H
Y
A
S
Site 238
S3442
S
R
I
E
H
Y
A
S
R
L
A
E
M
E
N
Site 239
S3450
R
L
A
E
M
E
N
S
N
G
S
Y
L
N
D
Site 240
Y3454
M
E
N
S
N
G
S
Y
L
N
D
S
I
S
P
Site 241
S3458
N
G
S
Y
L
N
D
S
I
S
P
N
E
S
I
Site 242
S3460
S
Y
L
N
D
S
I
S
P
N
E
S
I
D
D
Site 243
S3464
D
S
I
S
P
N
E
S
I
D
D
E
H
L
L
Site 244
Y3475
E
H
L
L
I
Q
H
Y
C
Q
S
L
N
Q
D
Site 245
S3478
L
I
Q
H
Y
C
Q
S
L
N
Q
D
S
P
L
Site 246
S3483
C
Q
S
L
N
Q
D
S
P
L
S
Q
P
R
S
Site 247
S3486
L
N
Q
D
S
P
L
S
Q
P
R
S
P
A
Q
Site 248
S3490
S
P
L
S
Q
P
R
S
P
A
Q
I
L
I
S
Site 249
S3497
S
P
A
Q
I
L
I
S
L
E
S
E
E
R
G
Site 250
S3500
Q
I
L
I
S
L
E
S
E
E
R
G
E
L
E
Site 251
Y3524
N
R
N
L
Q
A
E
Y
D
R
L
K
Q
Q
H
Site 252
S3537
Q
H
E
H
K
G
L
S
P
L
P
S
P
P
E
Site 253
S3541
K
G
L
S
P
L
P
S
P
P
E
M
M
P
T
Site 254
T3548
S
P
P
E
M
M
P
T
S
P
Q
S
P
R
D
Site 255
S3549
P
P
E
M
M
P
T
S
P
Q
S
P
R
D
A
Site 256
S3552
M
M
P
T
S
P
Q
S
P
R
D
A
E
L
I
Site 257
S3588
D
H
N
K
Q
L
E
S
Q
L
H
R
L
R
Q
Site 258
T3609
A
E
A
K
V
N
G
T
T
V
S
S
P
S
T
Site 259
T3610
E
A
K
V
N
G
T
T
V
S
S
P
S
T
S
Site 260
S3612
K
V
N
G
T
T
V
S
S
P
S
T
S
L
Q
Site 261
S3613
V
N
G
T
T
V
S
S
P
S
T
S
L
Q
R
Site 262
S3615
G
T
T
V
S
S
P
S
T
S
L
Q
R
S
D
Site 263
T3616
T
T
V
S
S
P
S
T
S
L
Q
R
S
D
S
Site 264
S3617
T
V
S
S
P
S
T
S
L
Q
R
S
D
S
S
Site 265
S3621
P
S
T
S
L
Q
R
S
D
S
S
Q
P
M
L
Site 266
S3623
T
S
L
Q
R
S
D
S
S
Q
P
M
L
L
R
Site 267
S3624
S
L
Q
R
S
D
S
S
Q
P
M
L
L
R
V
Site 268
S3637
R
V
V
G
S
Q
T
S
D
S
M
G
E
E
D
Site 269
S3639
V
G
S
Q
T
S
D
S
M
G
E
E
D
L
L
Site 270
S3647
M
G
E
E
D
L
L
S
P
P
Q
D
T
S
T
Site 271
T3652
L
L
S
P
P
Q
D
T
S
T
G
L
E
E
V
Site 272
T3654
S
P
P
Q
D
T
S
T
G
L
E
E
V
M
E
Site 273
S3666
V
M
E
Q
L
N
N
S
F
P
S
S
R
G
R
Site 274
S3669
Q
L
N
N
S
F
P
S
S
R
G
R
N
T
P
Site 275
S3670
L
N
N
S
F
P
S
S
R
G
R
N
T
P
G
Site 276
T3675
P
S
S
R
G
R
N
T
P
G
K
P
M
R
E
Site 277
T3684
G
K
P
M
R
E
D
T
M
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation