PhosphoNET

           
Protein Info 
   
Short Name:  EGR2
Full Name:  Early growth response protein 2
Alias:  AT591;Zinc finger protein Krox-20
Type: 
Mass (Da):  50302
Number AA:  476
UniProt ID:  P11161
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22SGFVHQLSDNIYPVE
Site 2Y26HQLSDNIYPVEDLAA
Site 3T65GMINIDMTGEKRSLD
Site 4S70DMTGEKRSLDLPYPS
Site 5Y75KRSLDLPYPSSFAPV
Site 6S83PSSFAPVSAPRNQTF
Site 7T89VSAPRNQTFTYMGKF
Site 8T91APRNQTFTYMGKFSI
Site 9Y92PRNQTFTYMGKFSID
Site 10Y102KFSIDPQYPGASCYP
Site 11S106DPQYPGASCYPEGII
Site 12Y108QYPGASCYPEGIINI
Site 13S129QGVTSPASTTASSSV
Site 14T130GVTSPASTTASSSVT
Site 15T131VTSPASTTASSSVTS
Site 16S133SPASTTASSSVTSAS
Site 17S134PASTTASSSVTSASP
Site 18S135ASTTASSSVTSASPN
Site 19T137TTASSSVTSASPNPL
Site 20S138TASSSVTSASPNPLA
Site 21S140SSSVTSASPNPLATG
Site 22T153TGPLGVCTMSQTQPD
Site 23S155PLGVCTMSQTQPDLD
Site 24T157GVCTMSQTQPDLDHL
Site 25Y165QPDLDHLYSPPPPPP
Site 26S166PDLDHLYSPPPPPPP
Site 27Y174PPPPPPPYSGCAGDL
Site 28S175PPPPPPYSGCAGDLY
Site 29Y182SGCAGDLYQDPSAFL
Site 30S186GDLYQDPSAFLSAAT
Site 31S190QDPSAFLSAATTSTS
Site 32S197SAATTSTSSSLAYPP
Site 33S199ATTSTSSSLAYPPPP
Site 34Y202STSSSLAYPPPPSYP
Site 35S207LAYPPPPSYPSPKPA
Site 36Y208AYPPPPSYPSPKPAT
Site 37S210PPPPSYPSPKPATDP
Site 38T215YPSPKPATDPGLFPM
Site 39T241CQRDLHGTAGPDRKP
Site 40T263LRVPPPLTPLSTIRN
Site 41T281GGPSAGVTGPGASGG
Site 42S289GPGASGGSEGPRLPG
Site 43S297EGPRLPGSSSAAAAA
Site 44Y326PILRPRKYPNRPSKT
Site 45S331RKYPNRPSKTPVHER
Site 46T333YPNRPSKTPVHERPY
Site 47Y340TPVHERPYPCPAEGC
Site 48S352EGCDRRFSRSDELTR
Site 49S354CDRRFSRSDELTRHI
Site 50T358FSRSDELTRHIRIHT
Site 51T365TRHIRIHTGHKPFQC
Site 52S380RICMRNFSRSDHLTT
Site 53T386FSRSDHLTTHIRTHT
Site 54T387SRSDHLTTHIRTHTG
Site 55T391HLTTHIRTHTGEKPF
Site 56T393TTHIRTHTGEKPFAC
Site 57Y402EKPFACDYCGRKFAR
Site 58S410CGRKFARSDERKRHT
Site 59T417SDERKRHTKIHLRQK
Site 60S428LRQKERKSSAPSASV
Site 61S429RQKERKSSAPSASVP
Site 62S432ERKSSAPSASVPAPS
Site 63S434KSSAPSASVPAPSTA
Site 64S439SASVPAPSTASCSGG
Site 65S442VPAPSTASCSGGVQP
Site 66S444APSTASCSGGVQPGG
Site 67T452GGVQPGGTLCSSNSS
Site 68S455QPGGTLCSSNSSSLG
Site 69S456PGGTLCSSNSSSLGG
Site 70S458GTLCSSNSSSLGGGP
Site 71S459TLCSSNSSSLGGGPL
Site 72S470GGPLAPCSSRTRTP_
Site 73S471GPLAPCSSRTRTP__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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