PhosphoNET

           
Protein Info 
   
Short Name:  IRF1
Full Name:  Interferon regulatory factor 1
Alias:  IRF-1
Type: 
Mass (Da):  36484
Number AA:  325
UniProt ID:  P10914
International Prot ID:  IPI00023600
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0003677  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0006139  GO:0006350  GO:0006351 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T62FRSWAIHTGRYKAGE
Site 2T76EKEPDPKTWKANFRC
Site 3S87NFRCAMNSLPDIEEV
Site 4S98IEEVKDQSRNKGSSA
Site 5S103DQSRNKGSSAVRVYR
Site 6S104QSRNKGSSAVRVYRM
Site 7Y109GSSAVRVYRMLPPLT
Site 8T116YRMLPPLTKNQRKER
Site 9S125NQRKERKSKSSRDAK
Site 10S127RKERKSKSSRDAKSK
Site 11S128KERKSKSSRDAKSKA
Site 12S133KSSRDAKSKAKRKSC
Site 13S139KSKAKRKSCGDSSPD
Site 14S143KRKSCGDSSPDTFSD
Site 15S144RKSCGDSSPDTFSDG
Site 16T147CGDSSPDTFSDGLSS
Site 17S149DSSPDTFSDGLSSST
Site 18S153DTFSDGLSSSTLPDD
Site 19S155FSDGLSSSTLPDDHS
Site 20T156SDGLSSSTLPDDHSS
Site 21S162STLPDDHSSYTVPGY
Site 22S163TLPDDHSSYTVPGYM
Site 23Y164LPDDHSSYTVPGYMQ
Site 24T165PDDHSSYTVPGYMQD
Site 25Y169SSYTVPGYMQDLEVE
Site 26T191SPCAVSSTLPDWHIP
Site 27S205PVEVVPDSTSDLYNF
Site 28S207EVVPDSTSDLYNFQV
Site 29Y210PDSTSDLYNFQVSPM
Site 30S215DLYNFQVSPMPSTSE
Site 31S219FQVSPMPSTSEATTD
Site 32S221VSPMPSTSEATTDED
Site 33T225PSTSEATTDEDEEGK
Site 34T249EQSEWQPTNVDGKGY
Site 35Y256TNVDGKGYLLNEPGV
Site 36S267EPGVQPTSVYGDFSC
Site 37Y269GVQPTSVYGDFSCKE
Site 38S273TSVYGDFSCKEEPEI
Site 39S282KEEPEIDSPGGDIGL
Site 40S290PGGDIGLSLQRVFTD
Site 41T296LSLQRVFTDLKNMDA
Site 42T304DLKNMDATWLDSLLT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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