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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_5q33.3 provirus ancestral Pol protein
Full Name:
HERV-K_5q33.3 provirus ancestral Pol protein
Alias:
HERV-K10 Pol protein;HERV-K107 Pol protein
Type:
Mass (Da):
114827
Number AA:
1014
UniProt ID:
P10266
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
K
R
R
N
R
V
S
F
L
G
A
V
T
V
Site 2
T27
P
P
K
P
I
P
L
T
W
K
T
E
K
P
V
Site 3
S65
E
K
G
H
I
E
P
S
F
S
P
W
N
S
P
Site 4
S67
G
H
I
E
P
S
F
S
P
W
N
S
P
V
F
Site 5
S71
P
S
F
S
P
W
N
S
P
V
F
V
I
Q
K
Site 6
T87
S
G
K
W
H
T
L
T
D
L
R
A
V
N
A
Site 7
S108
P
L
Q
P
G
L
P
S
P
A
M
I
P
K
D
Site 8
T174
N
S
P
T
I
C
Q
T
F
V
G
R
A
L
Q
Site 9
Y191
R
E
K
F
S
D
C
Y
I
I
H
Y
I
D
D
Site 10
Y213
K
D
K
L
I
D
C
Y
T
F
L
Q
A
E
V
Site 11
S235
A
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
Site 12
T236
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
M
Site 13
T261
K
I
E
I
R
K
D
T
L
K
T
L
N
D
F
Site 14
T264
I
R
K
D
T
L
K
T
L
N
D
F
Q
K
L
Site 15
T281
D
I
N
W
I
R
P
T
L
G
I
P
T
Y
A
Site 16
S294
Y
A
M
S
N
L
F
S
I
L
R
G
D
S
D
Site 17
S300
F
S
I
L
R
G
D
S
D
L
N
S
Q
R
I
Site 18
S304
R
G
D
S
D
L
N
S
Q
R
I
L
T
P
E
Site 19
T309
L
N
S
Q
R
I
L
T
P
E
A
T
K
E
I
Site 20
S362
N
T
D
L
V
E
W
S
F
L
P
H
S
T
V
Site 21
S367
E
W
S
F
L
P
H
S
T
V
K
T
F
T
L
Site 22
T371
L
P
H
S
T
V
K
T
F
T
L
Y
L
D
Q
Site 23
T391
G
Q
T
R
L
R
I
T
K
L
C
G
N
D
P
Site 24
Y435
V
G
L
I
D
N
H
Y
P
K
T
K
I
F
Q
Site 25
T465
E
P
L
E
N
A
L
T
V
F
T
D
G
S
S
Site 26
S471
L
T
V
F
T
D
G
S
S
N
G
K
A
A
Y
Site 27
Y478
S
S
N
G
K
A
A
Y
T
G
P
K
E
R
V
Site 28
T488
P
K
E
R
V
I
K
T
P
Y
Q
S
A
Q
R
Site 29
Y520
N
I
I
S
D
S
A
Y
V
V
Q
A
T
R
D
Site 30
S536
E
T
A
L
I
K
Y
S
M
D
D
Q
L
N
Q
Site 31
T551
L
F
N
L
L
Q
Q
T
V
R
K
R
N
F
P
Site 32
Y560
R
K
R
N
F
P
F
Y
I
T
Y
I
R
A
H
Site 33
Y563
N
F
P
F
Y
I
T
Y
I
R
A
H
T
N
L
Site 34
T568
I
T
Y
I
R
A
H
T
N
L
P
G
P
L
T
Site 35
T575
T
N
L
P
G
P
L
T
K
A
N
E
Q
A
D
Site 36
T655
A
L
W
Q
M
D
V
T
H
V
P
S
F
G
R
Site 37
Y665
P
S
F
G
R
L
S
Y
V
H
V
T
V
D
T
Site 38
T669
R
L
S
Y
V
H
V
T
V
D
T
Y
S
H
F
Site 39
S688
C
Q
T
G
E
S
T
S
H
V
K
K
H
L
L
Site 40
T709
G
V
P
E
K
I
K
T
D
N
G
P
G
Y
C
Site 41
Y715
K
T
D
N
G
P
G
Y
C
S
K
A
F
Q
K
Site 42
Y737
S
H
T
T
G
I
P
Y
N
S
Q
G
Q
A
I
Site 43
T754
R
T
N
R
T
L
K
T
Q
L
V
K
Q
K
E
Site 44
S765
K
Q
K
E
G
G
D
S
K
E
C
T
T
P
Q
Site 45
T769
G
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
Site 46
T770
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
L
Site 47
T792
L
N
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
Site 48
T794
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
L
T
Site 49
T801
T
S
A
E
Q
H
L
T
G
K
K
N
S
P
H
Site 50
S806
H
L
T
G
K
K
N
S
P
H
E
G
K
L
I
Site 51
S839
G
R
G
F
A
C
V
S
P
G
E
N
Q
L
P
Site 52
Y857
P
T
R
H
L
K
F
Y
N
E
P
I
G
D
A
Site 53
S869
G
D
A
K
K
R
A
S
T
E
M
V
T
P
V
Site 54
T870
D
A
K
K
R
A
S
T
E
M
V
T
P
V
T
Site 55
T874
R
A
S
T
E
M
V
T
P
V
T
W
M
D
N
Site 56
Y920
N
I
S
I
G
Y
R
Y
P
P
I
C
L
G
R
Site 57
Y954
S
P
I
S
R
F
T
Y
H
M
V
S
G
M
S
Site 58
S958
R
F
T
Y
H
M
V
S
G
M
S
L
R
P
R
Site 59
Y968
S
L
R
P
R
V
N
Y
L
Q
D
F
S
Y
Q
Site 60
S973
V
N
Y
L
Q
D
F
S
Y
Q
R
S
L
K
F
Site 61
Y974
N
Y
L
Q
D
F
S
Y
Q
R
S
L
K
F
R
Site 62
S977
Q
D
F
S
Y
Q
R
S
L
K
F
R
P
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation