PhosphoNET

           
Protein Info 
   
Short Name:  GLI3
Full Name:  Zinc finger protein GLI3
Alias:  ACLS; DNA-binding protein; GCPS; GLI family zinc finger 3; GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome); Oncogene GLI3; PAPA; PAP-A; PAPA1; PAPB; PHS; PPDIV
Type:  Transcription factor
Mass (Da):  169863
Number AA:  1580
UniProt ID:  P10071
International Prot ID:  IPI00018889
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005929  GO:0005737  GO:0005730 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003700  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0000060  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9EAQSHSSTTTEKKKV
Site 2T11QSHSSTTTEKKKVEN
Site 3S19EKKKVENSIVKCSTR
Site 4S24ENSIVKCSTRTDVSE
Site 5S36VSEKAVASSTTSNED
Site 6S40AVASSTTSNEDESPG
Site 7S45TTSNEDESPGQTYHR
Site 8T49EDESPGQTYHRERRN
Site 9Y50DESPGQTYHRERRNA
Site 10T59RERRNAITMQPQNVQ
Site 11S69PQNVQGLSKVSEEPS
Site 12S72VQGLSKVSEEPSTSS
Site 13S76SKVSEEPSTSSDERA
Site 14T77KVSEEPSTSSDERAS
Site 15S78VSEEPSTSSDERASL
Site 16S79SEEPSTSSDERASLI
Site 17S84TSSDERASLIKKEIH
Site 18S93IKKEIHGSLPHVAEP
Site 19S101LPHVAEPSVPYRGTV
Site 20T107PSVPYRGTVFAMDPR
Site 21Y117AMDPRNGYMEPHYHP
Site 22Y122NGYMEPHYHPPHLFP
Site 23Y148HHEGRYHYDPSPIPP
Site 24S151GRYHYDPSPIPPLHM
Site 25T159PIPPLHMTSALSSSP
Site 26S160IPPLHMTSALSSSPT
Site 27S163LHMTSALSSSPTYPD
Site 28S164HMTSALSSSPTYPDL
Site 29S165MTSALSSSPTYPDLP
Site 30T167SALSSSPTYPDLPFI
Site 31Y168ALSSSPTYPDLPFIR
Site 32S177DLPFIRISPHRNPAA
Site 33S186HRNPAAASESPFSPP
Site 34S188NPAAASESPFSPPHP
Site 35S191AASESPFSPPHPYIN
Site 36Y196PFSPPHPYINPYMDY
Site 37Y200PHPYINPYMDYIRSL
Site 38Y203YINPYMDYIRSLHSS
Site 39S206PYMDYIRSLHSSPSL
Site 40S209DYIRSLHSSPSLSMI
Site 41S210YIRSLHSSPSLSMIS
Site 42S212RSLHSSPSLSMISAT
Site 43S214LHSSPSLSMISATRG
Site 44S217SPSLSMISATRGLSP
Site 45T219SLSMISATRGLSPTD
Site 46S223ISATRGLSPTDAPHA
Site 47T225ATRGLSPTDAPHAGV
Site 48S233DAPHAGVSPAEYYHQ
Site 49T245YHQMALLTGQRSPYA
Site 50Y251LTGQRSPYADIIPSA
Site 51Y270TGAIHMEYLHAMDST
Site 52S276EYLHAMDSTRFSSPR
Site 53T277YLHAMDSTRFSSPRL
Site 54S280AMDSTRFSSPRLSAR
Site 55S281MDSTRFSSPRLSARP
Site 56S285RFSSPRLSARPSRKR
Site 57S289PRLSARPSRKRTLSI
Site 58T293ARPSRKRTLSISPLS
Site 59S295PSRKRTLSISPLSDH
Site 60S297RKRTLSISPLSDHSF
Site 61S300TLSISPLSDHSFDLQ
Site 62S303ISPLSDHSFDLQTMI
Site 63T308DHSFDLQTMIRTSPN
Site 64S324LVTILNNSRSSSSAS
Site 65S326TILNNSRSSSSASGS
Site 66S327ILNNSRSSSSASGSY
Site 67S328LNNSRSSSSASGSYG
Site 68S329NNSRSSSSASGSYGH
Site 69S331SRSSSSASGSYGHLS
Site 70S333SSSSASGSYGHLSAS
Site 71S338SGSYGHLSASAISPA
Site 72S356TYSSAPVSLHMHQQI
Site 73S365HMHQQILSRQQSLGS
Site 74S369QILSRQQSLGSAFGH
Site 75S372SRQQSLGSAFGHSPP
Site 76T386PLIHPAPTFPTQRPI
Site 77T389HPAPTFPTQRPIPGI
Site 78S406VLNPVQVSSGPSESS
Site 79S407LNPVQVSSGPSESSQ
Site 80S410VQVSSGPSESSQNKP
Site 81S412VSSGPSESSQNKPTS
Site 82S413SSGPSESSQNKPTSE
Site 83S419SSQNKPTSESAVSST
Site 84S421QNKPTSESAVSSTGD
Site 85S424PTSESAVSSTGDPMH
Site 86S425TSESAVSSTGDPMHN
Site 87T426SESAVSSTGDPMHNK
Site 88S445KPDEDLPSPGARGQQ
Site 89S470EEGDKDESKQEPEVI
Site 90Y478KQEPEVIYETNCHWE
Site 91T493GCAREFDTQEQLVHH
Site 92Y531QKPFKAQYMLVVHMR
Site 93T541VVHMRRHTGEKPHKC
Site 94T549GEKPHKCTFEGCTKA
Site 95T565SRLENLKTHLRSHTG
Site 96S569NLKTHLRSHTGEKPY
Site 97T571KTHLRSHTGEKPYVC
Site 98Y576SHTGEKPYVCEHEGC
Site 99S591NKAFSNASDRAKHQN
Site 100Y607THSNEKPYVCKIPGC
Site 101Y618IPGCTKRYTDPSSLR
Site 102T619PGCTKRYTDPSSLRK
Site 103S622TKRYTDPSSLRKHVK
Site 104S623KRYTDPSSLRKHVKT
Site 105T630SLRKHVKTVHGPEAH
Site 106T639HGPEAHVTKKQRGDI
Site 107S656RPPPPRDSGSHSQSR
Site 108S658PPPRDSGSHSQSRSP
Site 109S660PRDSGSHSQSRSPGR
Site 110S662DSGSHSQSRSPGRPT
Site 111S664GSHSQSRSPGRPTQG
Site 112T669SRSPGRPTQGALGEQ
Site 113S680LGEQQDLSNTTSKRE
Site 114S684QDLSNTTSKREECLQ
Site 115T694EECLQVKTVKAEKPM
Site 116T702VKAEKPMTSQPSPGG
Site 117S703KAEKPMTSQPSPGGQ
Site 118S706KPMTSQPSPGGQSSC
Site 119S711QPSPGGQSSCSSQQS
Site 120S712PSPGGQSSCSSQQSP
Site 121S714PGGQSSCSSQQSPIS
Site 122S715GGQSSCSSQQSPISN
Site 123S718SSCSSQQSPISNYSN
Site 124S721SSQQSPISNYSNSGL
Site 125Y723QQSPISNYSNSGLEL
Site 126S724QSPISNYSNSGLELP
Site 127S726PISNYSNSGLELPLT
Site 128T733SGLELPLTDGGSIGD
Site 129T772ARRNPAGTKWMEHVK
Site 130S805PPKAPAVSPLIGNGT
Site 131T812SPLIGNGTQSNNTCS
Site 132S814LIGNGTQSNNTCSLG
Site 133T817NGTQSNNTCSLGGPM
Site 134T825CSLGGPMTLLPGRSD
Site 135S849NMLNRRDSSASTISS
Site 136S850MLNRRDSSASTISSA
Site 137S852NRRDSSASTISSAYL
Site 138T853RRDSSASTISSAYLS
Site 139S855DSSASTISSAYLSSR
Site 140S856SSASTISSAYLSSRR
Site 141Y858ASTISSAYLSSRRSS
Site 142S860TISSAYLSSRRSSGI
Site 143S861ISSAYLSSRRSSGIS
Site 144S864AYLSSRRSSGISPCF
Site 145S865YLSSRRSSGISPCFS
Site 146S868SRRSSGISPCFSSRR
Site 147S872SGISPCFSSRRSSEA
Site 148S873GISPCFSSRRSSEAS
Site 149S876PCFSSRRSSEASQAE
Site 150S877CFSSRRSSEASQAEG
Site 151S880SRRSSEASQAEGRPQ
Site 152S890EGRPQNVSVADSYDP
Site 153S894QNVSVADSYDPISTD
Site 154Y895NVSVADSYDPISTDA
Site 155S899ADSYDPISTDASRRS
Site 156S903DPISTDASRRSSEAS
Site 157S906STDASRRSSEASQSD
Site 158S907TDASRRSSEASQSDG
Site 159S910SRRSSEASQSDGLPS
Site 160S912RSSEASQSDGLPSLL
Site 161S917SQSDGLPSLLSLTPA
Site 162S920DGLPSLLSLTPAQQY
Site 163Y933QYRLKAKYAAATGGP
Site 164T943ATGGPPPTPLPNMER
Site 165S952LPNMERMSLKTRLAL
Site 166T955MERMSLKTRLALLGD
Site 167S980VHAPRRCSDGGAHGY
Site 168Y987SDGGAHGYGRRHLQP
Site 169S1006GHGVRRASDPVRTGS
Site 170S1013SDPVRTGSEGLALPR
Site 171S1025LPRVPRFSSLSSCNP
Site 172S1026PRVPRFSSLSSCNPP
Site 173S1028VPRFSSLSSCNPPAM
Site 174S1029PRFSSLSSCNPPAMA
Site 175Y1049RSLVLQNYTRPEGGQ
Site 176S1057TRPEGGQSRNFHSSP
Site 177S1062GQSRNFHSSPCPPSI
Site 178S1063QSRNFHSSPCPPSIT
Site 179S1068HSSPCPPSITENVTL
Site 180T1070SPCPPSITENVTLES
Site 181T1074PSITENVTLESLTMD
Site 182Y1099LPDDVVQYLNSQNQA
Site 183S1102DVVQYLNSQNQAGYE
Site 184Y1108NSQNQAGYEQHFPSA
Site 185S1114GYEQHFPSALPDDSK
Site 186S1120PSALPDDSKVPHGPG
Site 187S1137DAPGLPDSHAGQQFH
Site 188S1154EQPCPEGSKTDLPIQ
Site 189T1156PCPEGSKTDLPIQWN
Site 190S1167IQWNEVSSGSADLSS
Site 191S1169WNEVSSGSADLSSSK
Site 192S1173SSGSADLSSSKLKCG
Site 193S1174SGSADLSSSKLKCGP
Site 194S1175GSADLSSSKLKCGPR
Site 195T1188PRPAVPQTRAFGFCN
Site 196S1207HPQNPLRSGPAGGYQ
Site 197Y1213RSGPAGGYQTLGENS
Site 198Y1223LGENSNPYGGPEHLM
Site 199S1234EHLMLHNSPGSGTSG
Site 200S1237MLHNSPGSGTSGNAF
Site 201Y1254QPCKAPQYGNCLNRQ
Site 202S1279CGAGIQASKLKSTPM
Site 203S1283IQASKLKSTPMQGSG
Site 204T1284QASKLKSTPMQGSGG
Site 205S1289KSTPMQGSGGQLNFG
Site 206S1307APNESAGSMVNGMQN
Site 207Y1322QDPVGQGYLAHQLLG
Site 208S1331AHQLLGDSMQHPGAG
Site 209S1352LGQISATSHINIYQG
Site 210Y1357ATSHINIYQGPESCL
Site 211S1362NIYQGPESCLPGAHG
Site 212S1372PGAHGMGSQPSSLAV
Site 213S1376GMGSQPSSLAVVRGY
Site 214S1388RGYQPCASFGGSRRQ
Site 215S1392PCASFGGSRRQAMPR
Site 216S1401RQAMPRDSLALQSGQ
Site 217S1406RDSLALQSGQLSDTS
Site 218S1410ALQSGQLSDTSQTCR
Site 219S1413SGQLSDTSQTCRVNG
Site 220S1434GQPHPLCSNLQNYSG
Site 221Y1444QNYSGQFYDQTVGFS
Site 222T1447SGQFYDQTVGFSQQD
Site 223T1455VGFSQQDTKAGSFSI
Site 224S1459QQDTKAGSFSISDAS
Site 225S1461DTKAGSFSISDASCL
Site 226S1473SCLLQGTSAKNSELL
Site 227S1477QGTSAKNSELLSPGA
Site 228S1481AKNSELLSPGANQVT
Site 229S1489PGANQVTSTVDSLDS
Site 230T1490GANQVTSTVDSLDSH
Site 231S1493QVTSTVDSLDSHDLE
Site 232S1496STVDSLDSHDLEGVQ
Site 233S1517IDDGDHSSLMSGALS
Site 234S1520GDHSSLMSGALSPSI
Site 235S1532PSIIQNLSHSSSRLT
Site 236S1534IIQNLSHSSSRLTTP
Site 237S1535IQNLSHSSSRLTTPR
Site 238S1536QNLSHSSSRLTTPRA
Site 239T1539SHSSSRLTTPRASLP
Site 240T1540HSSSRLTTPRASLPF
Site 241S1544RLTTPRASLPFPALS
Site 242T1567GDMSSLLTSLAEESK
Site 243S1568DMSSLLTSLAEESKF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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