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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC159
Full Name:
Coiled-coil domain-containing protein 159
Alias:
Type:
Mass (Da):
46012
Number AA:
412
UniProt ID:
P0C7I6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
G
L
P
R
D
P
D
Y
S
V
S
C
L
Y
S
Site 2
S20
L
P
R
D
P
D
Y
S
V
S
C
L
Y
S
P
Site 3
S22
R
D
P
D
Y
S
V
S
C
L
Y
S
P
P
S
Site 4
Y25
D
Y
S
V
S
C
L
Y
S
P
P
S
P
S
S
Site 5
S26
Y
S
V
S
C
L
Y
S
P
P
S
P
S
S
M
Site 6
S29
S
C
L
Y
S
P
P
S
P
S
S
M
C
L
P
Site 7
S31
L
Y
S
P
P
S
P
S
S
M
C
L
P
A
N
Site 8
S32
Y
S
P
P
S
P
S
S
M
C
L
P
A
N
M
Site 9
Y44
A
N
M
K
C
D
K
Y
W
G
S
S
S
D
K
Site 10
S47
K
C
D
K
Y
W
G
S
S
S
D
K
A
L
E
Site 11
S49
D
K
Y
W
G
S
S
S
D
K
A
L
E
R
T
Site 12
S60
L
E
R
T
A
H
W
S
R
T
P
E
P
E
T
Site 13
T62
R
T
A
H
W
S
R
T
P
E
P
E
T
L
G
Site 14
T67
S
R
T
P
E
P
E
T
L
G
C
P
A
S
G
Site 15
S73
E
T
L
G
C
P
A
S
G
D
T
V
R
T
A
Site 16
T76
G
C
P
A
S
G
D
T
V
R
T
A
D
C
R
Site 17
S88
D
C
R
P
G
W
G
S
G
P
S
P
H
E
A
Site 18
S91
P
G
W
G
S
G
P
S
P
H
E
A
A
P
S
Site 19
S98
S
P
H
E
A
A
P
S
P
S
P
D
L
Q
K
Site 20
S100
H
E
A
A
P
S
P
S
P
D
L
Q
K
Q
C
Site 21
T127
V
A
K
K
P
L
E
T
S
S
S
K
V
K
A
Site 22
S129
K
K
P
L
E
T
S
S
S
K
V
K
A
K
T
Site 23
S130
K
P
L
E
T
S
S
S
K
V
K
A
K
T
I
Site 24
T136
S
S
K
V
K
A
K
T
I
V
M
I
P
D
S
Site 25
S153
L
L
R
C
E
L
E
S
L
K
S
Q
L
Q
A
Site 26
S156
C
E
L
E
S
L
K
S
Q
L
Q
A
Q
T
K
Site 27
S171
A
F
E
F
L
N
H
S
V
T
M
L
E
K
E
Site 28
T173
E
F
L
N
H
S
V
T
M
L
E
K
E
S
C
Site 29
S194
Q
Q
L
E
E
V
L
S
P
T
G
R
Q
G
E
Site 30
Y217
E
Q
G
R
Q
E
L
Y
G
A
L
T
Q
G
L
Site 31
T230
G
L
Q
G
L
E
K
T
L
R
D
S
E
E
M
Site 32
S234
L
E
K
T
L
R
D
S
E
E
M
Q
R
A
R
Site 33
T242
E
E
M
Q
R
A
R
T
T
R
C
L
Q
L
L
Site 34
T243
E
M
Q
R
A
R
T
T
R
C
L
Q
L
L
A
Site 35
S256
L
A
Q
E
I
R
D
S
K
K
F
L
W
E
E
Site 36
S286
Q
A
Q
E
D
E
I
S
E
N
L
V
N
I
Q
Site 37
T298
N
I
Q
K
M
Q
K
T
Q
V
K
C
R
K
I
Site 38
S342
D
D
L
Q
K
E
L
S
D
I
W
S
A
V
H
Site 39
S346
K
E
L
S
D
I
W
S
A
V
H
V
L
Q
N
Site 40
S369
S
G
A
C
P
K
A
S
S
L
R
G
H
K
G
Site 41
S370
G
A
C
P
K
A
S
S
L
R
G
H
K
G
H
Site 42
S381
H
K
G
H
Q
C
L
S
P
P
L
P
S
W
D
Site 43
S386
C
L
S
P
P
L
P
S
W
D
S
D
S
D
C
Site 44
S389
P
P
L
P
S
W
D
S
D
S
D
C
D
Q
D
Site 45
S391
L
P
S
W
D
S
D
S
D
C
D
Q
D
L
S
Site 46
S398
S
D
C
D
Q
D
L
S
Q
P
P
F
S
K
S
Site 47
S403
D
L
S
Q
P
P
F
S
K
S
G
R
S
F
P
Site 48
S405
S
Q
P
P
F
S
K
S
G
R
S
F
P
P
A
Site 49
S408
P
F
S
K
S
G
R
S
F
P
P
A
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation