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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOXC6
Full Name:
Homeobox protein Hox-C6
Alias:
Homeobox protein CP25;Homeobox protein HHO.C8;Homeobox protein Hox-3C
Type:
Mass (Da):
26915
Number AA:
235
UniProt ID:
P09630
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
N
S
Y
F
T
N
P
S
L
S
C
H
L
A
G
Site 2
S11
Y
F
T
N
P
S
L
S
C
H
L
A
G
G
Q
Site 3
Y31
V
A
L
N
S
T
A
Y
D
P
V
R
H
F
S
Site 4
S38
Y
D
P
V
R
H
F
S
T
Y
G
A
A
V
A
Site 5
Y40
P
V
R
H
F
S
T
Y
G
A
A
V
A
Q
N
Site 6
Y50
A
V
A
Q
N
R
I
Y
S
T
P
F
Y
S
P
Site 7
S51
V
A
Q
N
R
I
Y
S
T
P
F
Y
S
P
Q
Site 8
T52
A
Q
N
R
I
Y
S
T
P
F
Y
S
P
Q
E
Site 9
Y55
R
I
Y
S
T
P
F
Y
S
P
Q
E
N
V
V
Site 10
S56
I
Y
S
T
P
F
Y
S
P
Q
E
N
V
V
F
Site 11
S64
P
Q
E
N
V
V
F
S
S
S
R
G
P
Y
D
Site 12
S65
Q
E
N
V
V
F
S
S
S
R
G
P
Y
D
Y
Site 13
S66
E
N
V
V
F
S
S
S
R
G
P
Y
D
Y
G
Site 14
Y70
F
S
S
S
R
G
P
Y
D
Y
G
S
N
S
F
Site 15
Y72
S
S
R
G
P
Y
D
Y
G
S
N
S
F
Y
Q
Site 16
S74
R
G
P
Y
D
Y
G
S
N
S
F
Y
Q
E
K
Site 17
Y78
D
Y
G
S
N
S
F
Y
Q
E
K
D
M
L
S
Site 18
T91
L
S
N
C
R
Q
N
T
L
G
H
N
T
Q
T
Site 19
S106
S
I
A
Q
D
F
S
S
E
Q
G
R
T
A
P
Site 20
S133
M
Q
R
M
N
S
H
S
G
V
G
Y
G
A
D
Site 21
Y137
N
S
H
S
G
V
G
Y
G
A
D
R
R
R
G
Site 22
Y148
R
R
R
G
R
Q
I
Y
S
R
Y
Q
T
L
E
Site 23
S149
R
R
G
R
Q
I
Y
S
R
Y
Q
T
L
E
L
Site 24
Y151
G
R
Q
I
Y
S
R
Y
Q
T
L
E
L
E
K
Site 25
T153
Q
I
Y
S
R
Y
Q
T
L
E
L
E
K
E
F
Site 26
Y165
K
E
F
H
F
N
R
Y
L
T
R
R
R
R
I
Site 27
T167
F
H
F
N
R
Y
L
T
R
R
R
R
I
E
I
Site 28
S200
R
M
K
W
K
K
E
S
N
L
T
S
T
L
S
Site 29
T203
W
K
K
E
S
N
L
T
S
T
L
S
G
G
G
Site 30
S204
K
K
E
S
N
L
T
S
T
L
S
G
G
G
G
Site 31
T205
K
E
S
N
L
T
S
T
L
S
G
G
G
G
G
Site 32
S207
S
N
L
T
S
T
L
S
G
G
G
G
G
A
T
Site 33
T214
S
G
G
G
G
G
A
T
A
D
S
L
G
G
K
Site 34
S217
G
G
G
A
T
A
D
S
L
G
G
K
E
E
K
Site 35
T228
K
E
E
K
R
E
E
T
E
E
E
K
Q
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation