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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNP
Full Name:
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Alias:
CN37; CNPase; EC 3.1.4.37
Type:
Uncharacterized protein
Mass (Da):
47579
Number AA:
421
UniProt ID:
P09543
International Prot ID:
IsofromCNPI - IPI00220993
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0042470
Uniprot
OncoNet
Molecular Function:
GO:0004113
PhosphoSite+
KinaseNET
Biological Process:
GO:0016070
GO:0009214
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
N
R
G
F
S
R
K
S
H
T
F
L
Site 2
S9
N
R
G
F
S
R
K
S
H
T
F
L
P
K
I
Site 3
T11
G
F
S
R
K
S
H
T
F
L
P
K
I
F
F
Site 4
S22
K
I
F
F
R
K
M
S
S
S
G
A
K
D
K
Site 5
S24
F
F
R
K
M
S
S
S
G
A
K
D
K
P
E
Site 6
S61
I
L
R
G
L
P
G
S
G
K
S
T
L
A
R
Site 7
Y74
A
R
V
I
V
D
K
Y
R
D
G
T
K
M
V
Site 8
T78
V
D
K
Y
R
D
G
T
K
M
V
S
A
D
A
Site 9
Y86
K
M
V
S
A
D
A
Y
K
I
T
P
G
A
R
Site 10
T89
S
A
D
A
Y
K
I
T
P
G
A
R
G
A
F
Site 11
S97
P
G
A
R
G
A
F
S
E
E
Y
K
R
L
D
Site 12
Y100
R
G
A
F
S
E
E
Y
K
R
L
D
E
D
L
Site 13
Y110
L
D
E
D
L
A
A
Y
C
R
R
R
D
I
R
Site 14
T124
R
I
L
V
L
D
D
T
N
H
E
R
E
R
L
Site 15
Y141
L
F
E
M
A
D
Q
Y
Q
Y
Q
V
V
L
V
Site 16
Y143
E
M
A
D
Q
Y
Q
Y
Q
V
V
L
V
E
P
Site 17
S170
E
K
N
Q
W
Q
L
S
A
D
D
L
K
K
L
Site 18
Y189
E
K
D
F
L
P
L
Y
F
G
W
F
L
T
K
Site 19
T195
L
Y
F
G
W
F
L
T
K
K
S
S
E
T
L
Site 20
S198
G
W
F
L
T
K
K
S
S
E
T
L
R
K
A
Site 21
S199
W
F
L
T
K
K
S
S
E
T
L
R
K
A
G
Site 22
T201
L
T
K
K
S
S
E
T
L
R
K
A
G
Q
V
Site 23
T240
R
E
K
M
D
L
V
T
Y
F
G
K
R
P
P
Site 24
Y241
E
K
M
D
L
V
T
Y
F
G
K
R
P
P
G
Site 25
Y259
C
T
T
K
F
C
D
Y
G
K
A
P
G
A
E
Site 26
Y268
K
A
P
G
A
E
E
Y
A
Q
Q
D
V
L
K
Site 27
S277
Q
Q
D
V
L
K
K
S
Y
S
K
A
F
T
L
Site 28
S279
D
V
L
K
K
S
Y
S
K
A
F
T
L
T
I
Site 29
T295
A
L
F
V
T
P
K
T
T
G
A
R
V
E
L
Site 30
S303
T
G
A
R
V
E
L
S
E
Q
Q
L
Q
L
W
Site 31
S312
Q
Q
L
Q
L
W
P
S
D
V
D
K
L
S
P
Site 32
S318
P
S
D
V
D
K
L
S
P
T
D
N
L
P
R
Site 33
S327
T
D
N
L
P
R
G
S
R
A
H
I
T
L
G
Site 34
S359
L
R
Q
E
K
G
G
S
R
G
E
E
V
G
E
Site 35
S368
G
E
E
V
G
E
L
S
R
G
K
L
Y
S
L
Site 36
Y373
E
L
S
R
G
K
L
Y
S
L
G
N
G
R
W
Site 37
S374
L
S
R
G
K
L
Y
S
L
G
N
G
R
W
M
Site 38
T383
G
N
G
R
W
M
L
T
L
A
K
N
M
E
V
Site 39
Y397
V
R
A
I
F
T
G
Y
Y
G
K
G
K
P
V
Site 40
Y398
R
A
I
F
T
G
Y
Y
G
K
G
K
P
V
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation