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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP10
Full Name:
Stromelysin-2
Alias:
Matrix metalloproteinase-10;Transin-2
Type:
Mass (Da):
54151
Number AA:
476
UniProt ID:
P09238
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
V
C
S
A
Y
P
L
S
G
A
A
K
E
E
D
Site 2
Y37
N
K
D
L
A
Q
Q
Y
L
E
K
Y
Y
N
L
Site 3
Y41
A
Q
Q
Y
L
E
K
Y
Y
N
L
E
K
D
V
Site 4
S56
K
Q
F
R
R
K
D
S
N
L
I
V
K
K
I
Site 5
T82
T
G
K
L
D
T
D
T
L
E
V
M
R
K
P
Site 6
S100
V
P
D
V
G
H
F
S
S
F
P
G
M
P
K
Site 7
S101
P
D
V
G
H
F
S
S
F
P
G
M
P
K
W
Site 8
Y120
L
T
Y
R
I
V
N
Y
T
P
D
L
P
R
D
Site 9
T121
T
Y
R
I
V
N
Y
T
P
D
L
P
R
D
A
Site 10
S131
L
P
R
D
A
V
D
S
A
I
E
K
A
L
K
Site 11
T147
W
E
E
V
T
P
L
T
F
S
R
L
Y
E
G
Site 12
Y152
P
L
T
F
S
R
L
Y
E
G
E
A
D
I
M
Site 13
Y171
V
K
E
H
G
D
F
Y
S
F
D
G
P
G
H
Site 14
S172
K
E
H
G
D
F
Y
S
F
D
G
P
G
H
S
Site 15
S179
S
F
D
G
P
G
H
S
L
A
H
A
Y
P
P
Site 16
Y184
G
H
S
L
A
H
A
Y
P
P
G
P
G
L
Y
Site 17
Y236
A
N
T
E
A
L
M
Y
P
L
Y
N
S
F
T
Site 18
S251
E
L
A
Q
F
R
L
S
Q
D
D
V
N
G
I
Site 19
S260
D
D
V
N
G
I
Q
S
L
Y
G
P
P
P
A
Site 20
Y262
V
N
G
I
Q
S
L
Y
G
P
P
P
A
S
T
Site 21
S268
L
Y
G
P
P
P
A
S
T
E
E
P
L
V
P
Site 22
S278
E
P
L
V
P
T
K
S
V
P
S
G
S
E
M
Site 23
S283
T
K
S
V
P
S
G
S
E
M
P
A
K
C
D
Site 24
Y305
I
S
T
L
R
G
E
Y
L
F
F
K
D
R
Y
Site 25
S329
E
P
E
F
H
L
I
S
A
F
W
P
S
L
P
Site 26
Y343
P
S
Y
L
D
A
A
Y
E
V
N
S
R
D
T
Site 27
T350
Y
E
V
N
S
R
D
T
V
F
I
F
K
G
N
Site 28
Y371
G
N
E
V
Q
A
G
Y
P
R
G
I
H
T
L
Site 29
T377
G
Y
P
R
G
I
H
T
L
G
F
P
P
T
I
Site 30
T383
H
T
L
G
F
P
P
T
I
R
K
I
D
A
A
Site 31
S392
R
K
I
D
A
A
V
S
D
K
E
K
K
K
T
Site 32
T399
S
D
K
E
K
K
K
T
Y
F
F
A
A
D
K
Site 33
Y400
D
K
E
K
K
K
T
Y
F
F
A
A
D
K
Y
Site 34
Y407
Y
F
F
A
A
D
K
Y
W
R
F
D
E
N
S
Site 35
S416
R
F
D
E
N
S
Q
S
M
E
Q
G
F
P
R
Site 36
T465
D
P
N
A
R
M
V
T
H
I
L
K
S
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation