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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABHD2
Full Name:
Abhydrolase domain-containing protein 2
Alias:
Lung alpha/beta hydrolase 2;Protein PHPS1-2
Type:
Mass (Da):
48315
Number AA:
425
UniProt ID:
P08910
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
A
A
V
A
A
V
L
Y
V
I
V
R
C
L
N
Site 2
S37
V
R
C
L
N
L
K
S
P
T
A
P
P
D
L
Site 3
T39
C
L
N
L
K
S
P
T
A
P
P
D
L
Y
F
Site 4
Y45
P
T
A
P
P
D
L
Y
F
Q
D
S
G
L
S
Site 5
S49
P
D
L
Y
F
Q
D
S
G
L
S
R
F
L
L
Site 6
S52
Y
F
Q
D
S
G
L
S
R
F
L
L
K
S
C
Site 7
Y83
G
H
I
Q
T
A
L
Y
G
K
M
G
R
V
R
Site 8
S91
G
K
M
G
R
V
R
S
P
H
P
Y
G
H
R
Site 9
Y95
R
V
R
S
P
H
P
Y
G
H
R
K
F
I
T
Site 10
T102
Y
G
H
R
K
F
I
T
M
S
D
G
A
T
S
Site 11
S104
H
R
K
F
I
T
M
S
D
G
A
T
S
T
F
Site 12
T110
M
S
D
G
A
T
S
T
F
D
L
F
E
P
L
Site 13
Y142
A
N
H
S
E
K
Q
Y
I
R
T
F
V
D
Y
Site 14
T145
S
E
K
Q
Y
I
R
T
F
V
D
Y
A
Q
K
Site 15
Y149
Y
I
R
T
F
V
D
Y
A
Q
K
N
G
Y
R
Site 16
Y155
D
Y
A
Q
K
N
G
Y
R
C
A
V
L
N
H
Site 17
T172
A
L
P
N
I
E
L
T
S
P
R
M
F
T
Y
Site 18
S173
L
P
N
I
E
L
T
S
P
R
M
F
T
Y
G
Site 19
Y191
E
F
G
A
M
V
N
Y
I
K
K
T
Y
P
L
Site 20
Y216
G
G
N
I
V
C
K
Y
L
G
E
T
Q
A
N
Site 21
T245
S
A
L
R
A
Q
E
T
F
M
Q
W
D
Q
C
Site 22
S270
N
M
K
K
I
I
L
S
H
R
Q
A
L
F
G
Site 23
S285
D
H
V
K
K
P
Q
S
L
E
D
T
D
L
S
Site 24
T289
K
P
Q
S
L
E
D
T
D
L
S
R
L
Y
T
Site 25
S292
S
L
E
D
T
D
L
S
R
L
Y
T
A
T
S
Site 26
Y295
D
T
D
L
S
R
L
Y
T
A
T
S
L
M
Q
Site 27
S299
S
R
L
Y
T
A
T
S
L
M
Q
I
D
D
N
Site 28
Y314
V
M
R
K
F
H
G
Y
N
S
L
K
E
Y
Y
Site 29
S316
R
K
F
H
G
Y
N
S
L
K
E
Y
Y
E
E
Site 30
Y320
G
Y
N
S
L
K
E
Y
Y
E
E
E
S
C
M
Site 31
Y321
Y
N
S
L
K
E
Y
Y
E
E
E
S
C
M
R
Site 32
Y329
E
E
E
S
C
M
R
Y
L
H
R
I
Y
V
P
Site 33
Y334
M
R
Y
L
H
R
I
Y
V
P
L
M
L
V
N
Site 34
S351
D
D
P
L
V
H
E
S
L
L
T
I
P
K
S
Site 35
S358
S
L
L
T
I
P
K
S
L
S
E
K
R
E
N
Site 36
S360
L
T
I
P
K
S
L
S
E
K
R
E
N
V
M
Site 37
S415
E
R
N
K
L
Q
C
S
D
T
E
Q
V
E
A
Site 38
T417
N
K
L
Q
C
S
D
T
E
Q
V
E
A
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation