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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MFI2
Full Name:
Melanotransferrin
Alias:
CD228; FLJ38863; MAp97; MTF1; p97, melanom aassociated
Type:
Extracellular region, Plasma membrane, Integral plasma membrane protein
Mass (Da):
80242
Number AA:
738
UniProt ID:
P08582
International Prot ID:
IPI00029275
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005576
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0008199
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006879
GO:0006826
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S51
R
E
A
G
I
Q
P
S
L
L
C
V
R
G
T
Site 2
Y83
T
L
D
G
G
A
I
Y
E
A
G
K
E
H
G
Site 3
Y99
K
P
V
V
G
E
V
Y
D
Q
E
V
G
T
S
Site 4
Y107
D
Q
E
V
G
T
S
Y
Y
A
V
A
V
V
R
Site 5
T120
V
R
R
S
S
H
V
T
I
D
T
L
K
G
V
Site 6
T123
S
S
H
V
T
I
D
T
L
K
G
V
K
S
C
Site 7
S129
D
T
L
K
G
V
K
S
C
H
T
G
I
N
R
Site 8
S180
V
P
G
A
G
E
T
S
Y
S
E
S
L
C
R
Site 9
Y181
P
G
A
G
E
T
S
Y
S
E
S
L
C
R
L
Site 10
S182
G
A
G
E
T
S
Y
S
E
S
L
C
R
L
C
Site 11
S184
G
E
T
S
Y
S
E
S
L
C
R
L
C
R
G
Site 12
S193
C
R
L
C
R
G
D
S
S
G
E
G
V
C
D
Site 13
S194
R
L
C
R
G
D
S
S
G
E
G
V
C
D
K
Site 14
S202
G
E
G
V
C
D
K
S
P
L
E
R
Y
Y
D
Site 15
Y207
D
K
S
P
L
E
R
Y
Y
D
Y
S
G
A
F
Site 16
Y208
K
S
P
L
E
R
Y
Y
D
Y
S
G
A
F
R
Site 17
Y210
P
L
E
R
Y
Y
D
Y
S
G
A
F
R
C
L
Site 18
S211
L
E
R
Y
Y
D
Y
S
G
A
F
R
C
L
A
Site 19
T240
L
E
N
T
D
G
K
T
L
P
S
W
G
Q
A
Site 20
S261
E
L
L
C
R
D
G
S
R
A
D
V
T
E
W
Site 21
S304
N
E
G
Q
R
L
F
S
H
E
G
S
S
F
Q
Site 22
S308
R
L
F
S
H
E
G
S
S
F
Q
M
F
S
S
Site 23
S309
L
F
S
H
E
G
S
S
F
Q
M
F
S
S
E
Site 24
S315
S
S
F
Q
M
F
S
S
E
A
Y
G
Q
K
D
Site 25
Y318
Q
M
F
S
S
E
A
Y
G
Q
K
D
L
L
F
Site 26
S328
K
D
L
L
F
K
D
S
T
S
E
L
V
P
I
Site 27
Y340
V
P
I
A
T
Q
T
Y
E
A
W
L
G
H
E
Site 28
Y348
E
A
W
L
G
H
E
Y
L
H
A
M
K
G
L
Site 29
Y365
D
P
N
R
L
P
P
Y
L
R
W
C
V
L
S
Site 30
S399
K
P
E
I
Q
C
V
S
A
K
S
P
Q
H
C
Site 31
T419
A
E
Q
V
D
A
V
T
L
S
G
E
D
I
Y
Site 32
Y426
T
L
S
G
E
D
I
Y
T
A
G
K
K
Y
G
Site 33
T427
L
S
G
E
D
I
Y
T
A
G
K
K
Y
G
L
Site 34
Y451
P
E
D
S
S
N
S
Y
Y
V
V
A
V
V
R
Site 35
Y452
E
D
S
S
N
S
Y
Y
V
V
A
V
V
R
R
Site 36
S461
V
A
V
V
R
R
D
S
S
H
A
F
T
L
D
Site 37
S462
A
V
V
R
R
D
S
S
H
A
F
T
L
D
E
Site 38
T466
R
D
S
S
H
A
F
T
L
D
E
L
R
G
K
Site 39
S475
D
E
L
R
G
K
R
S
C
H
A
G
F
G
S
Site 40
S482
S
C
H
A
G
F
G
S
P
A
G
W
D
V
P
Site 41
T508
P
K
D
C
D
V
L
T
A
V
S
E
F
F
N
Site 42
Y527
P
V
N
N
P
K
N
Y
P
S
S
L
C
A
L
Site 43
S530
N
P
K
N
Y
P
S
S
L
C
A
L
C
V
G
Site 44
Y553
V
G
N
S
Q
E
R
Y
Y
G
Y
R
G
A
F
Site 45
Y554
G
N
S
Q
E
R
Y
Y
G
Y
R
G
A
F
R
Site 46
Y556
S
Q
E
R
Y
Y
G
Y
R
G
A
F
R
C
L
Site 47
T576
D
V
A
F
V
R
H
T
T
V
F
D
N
T
N
Site 48
T577
V
A
F
V
R
H
T
T
V
F
D
N
T
N
G
Site 49
Y599
A
E
L
R
S
E
D
Y
E
L
L
C
P
N
G
Site 50
S612
N
G
A
R
A
E
V
S
Q
F
A
A
C
N
L
Site 51
T637
R
P
D
T
N
I
F
T
V
Y
G
L
L
D
K
Site 52
T687
A
V
P
V
G
E
K
T
T
Y
R
G
W
L
G
Site 53
T688
V
P
V
G
E
K
T
T
Y
R
G
W
L
G
L
Site 54
Y689
P
V
G
E
K
T
T
Y
R
G
W
L
G
L
D
Site 55
S706
A
A
L
E
G
M
S
S
Q
Q
C
S
G
A
A
Site 56
S710
G
M
S
S
Q
Q
C
S
G
A
A
A
P
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation