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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMB1
Full Name:
Laminin subunit beta-1
Alias:
Laminin B1 chain;Laminin-1 subunit beta;Laminin-10 subunit beta;Laminin-12 subunit beta;Laminin-2 subunit beta;Laminin-6 subunit beta;Laminin-8 subunit beta
Type:
Mass (Da):
198048
Number AA:
1786
UniProt ID:
P07942
International Prot ID:
IPI00013976
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005578
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005201
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000902
GO:0007155
GO:0008284
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
R
A
Q
E
P
E
F
S
Y
G
C
A
E
G
S
Site 2
Y28
A
Q
E
P
E
F
S
Y
G
C
A
E
G
S
C
Site 3
S34
S
Y
G
C
A
E
G
S
C
Y
P
A
T
G
D
Site 4
T39
E
G
S
C
Y
P
A
T
G
D
L
L
I
G
R
Site 5
T55
Q
K
L
S
V
T
S
T
C
G
L
H
K
P
E
Site 6
Y64
G
L
H
K
P
E
P
Y
C
I
V
S
H
L
Q
Site 7
Y85
I
C
N
S
Q
D
P
Y
H
E
T
L
N
P
D
Site 8
T88
S
Q
D
P
Y
H
E
T
L
N
P
D
S
H
L
Site 9
S93
H
E
T
L
N
P
D
S
H
L
I
E
N
V
V
Site 10
S154
A
M
L
I
E
R
S
S
D
F
G
K
T
W
G
Site 11
Y165
K
T
W
G
V
Y
R
Y
F
A
Y
D
C
E
A
Site 12
Y168
G
V
Y
R
Y
F
A
Y
D
C
E
A
S
F
P
Site 13
S178
E
A
S
F
P
G
I
S
T
G
P
M
K
K
V
Site 14
S192
V
D
D
I
I
C
D
S
R
Y
S
D
I
E
P
Site 15
Y194
D
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
Site 16
S195
I
I
C
D
S
R
Y
S
D
I
E
P
S
T
E
Site 17
S200
R
Y
S
D
I
E
P
S
T
E
G
E
V
I
F
Site 18
Y220
A
F
K
I
E
D
P
Y
S
P
R
I
Q
N
L
Site 19
S221
F
K
I
E
D
P
Y
S
P
R
I
Q
N
L
L
Site 20
T231
I
Q
N
L
L
K
I
T
N
L
R
I
K
F
V
Site 21
T242
I
K
F
V
K
L
H
T
L
G
D
N
L
L
D
Site 22
S250
L
G
D
N
L
L
D
S
R
M
E
I
R
E
K
Site 23
Y258
R
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
Site 24
Y259
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
V
Site 25
Y260
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
V
V
Site 26
Y263
E
K
Y
Y
Y
A
V
Y
D
M
V
V
R
G
N
Site 27
S329
R
P
A
E
G
R
N
S
N
A
C
K
K
C
N
Site 28
Y381
C
E
Q
C
K
P
F
Y
Y
Q
H
P
E
R
D
Site 29
Y382
E
Q
C
K
P
F
Y
Y
Q
H
P
E
R
D
I
Site 30
S413
Q
N
E
G
I
C
D
S
Y
T
D
F
S
T
G
Site 31
Y414
N
E
G
I
C
D
S
Y
T
D
F
S
T
G
L
Site 32
T419
D
S
Y
T
D
F
S
T
G
L
I
A
G
Q
C
Site 33
Y445
D
V
C
K
E
G
F
Y
D
L
S
S
E
D
P
Site 34
S448
K
E
G
F
Y
D
L
S
S
E
D
P
F
G
C
Site 35
S449
E
G
F
Y
D
L
S
S
E
D
P
F
G
C
K
Site 36
Y480
D
S
E
T
G
H
C
Y
C
K
R
L
V
T
G
Site 37
S501
L
P
E
H
W
G
L
S
N
D
L
D
G
C
R
Site 38
S521
L
G
G
A
L
N
N
S
C
F
A
E
S
G
Q
Site 39
Y547
C
N
E
V
E
P
G
Y
Y
F
A
T
L
D
H
Site 40
Y548
N
E
V
E
P
G
Y
Y
F
A
T
L
D
H
Y
Site 41
Y555
Y
F
A
T
L
D
H
Y
L
Y
E
A
E
E
A
Site 42
Y557
A
T
L
D
H
Y
L
Y
E
A
E
E
A
N
L
Site 43
Y575
V
S
I
V
E
R
Q
Y
I
Q
D
R
I
P
S
Site 44
S582
Y
I
Q
D
R
I
P
S
W
T
G
A
G
F
V
Site 45
T584
Q
D
R
I
P
S
W
T
G
A
G
F
V
R
V
Site 46
Y616
E
Y
D
I
L
I
R
Y
E
P
Q
L
P
D
H
Site 47
T639
Q
R
P
G
R
I
P
T
S
S
R
C
G
N
T
Site 48
S640
R
P
G
R
I
P
T
S
S
R
C
G
N
T
I
Site 49
S641
P
G
R
I
P
T
S
S
R
C
G
N
T
I
P
Site 50
S656
D
D
D
N
Q
V
V
S
L
S
P
G
S
R
Y
Site 51
S658
D
N
Q
V
V
S
L
S
P
G
S
R
Y
V
V
Site 52
Y663
S
L
S
P
G
S
R
Y
V
V
L
P
R
P
V
Site 53
Y678
C
F
E
K
G
T
N
Y
T
V
R
L
E
L
P
Site 54
T679
F
E
K
G
T
N
Y
T
V
R
L
E
L
P
Q
Site 55
Y687
V
R
L
E
L
P
Q
Y
T
S
S
D
S
D
V
Site 56
S689
L
E
L
P
Q
Y
T
S
S
D
S
D
V
E
S
Site 57
S690
E
L
P
Q
Y
T
S
S
D
S
D
V
E
S
P
Site 58
S692
P
Q
Y
T
S
S
D
S
D
V
E
S
P
Y
T
Site 59
S696
S
S
D
S
D
V
E
S
P
Y
T
L
I
D
S
Site 60
S729
G
D
G
V
V
T
N
S
A
W
E
T
F
Q
R
Site 61
Y737
A
W
E
T
F
Q
R
Y
R
C
L
E
N
S
R
Site 62
S743
R
Y
R
C
L
E
N
S
R
S
V
V
K
T
P
Site 63
S745
R
C
L
E
N
S
R
S
V
V
K
T
P
M
T
Site 64
T749
N
S
R
S
V
V
K
T
P
M
T
D
V
C
R
Site 65
S780
C
E
C
D
P
Q
G
S
L
S
S
V
C
D
P
Site 66
S782
C
D
P
Q
G
S
L
S
S
V
C
D
P
N
G
Site 67
S783
D
P
Q
G
S
L
S
S
V
C
D
P
N
G
G
Site 68
T810
C
N
R
C
A
P
G
T
F
G
F
G
P
S
G
Site 69
Y903
E
R
C
L
A
G
Y
Y
G
D
P
I
I
G
S
Site 70
S925
P
C
P
D
G
P
D
S
G
R
Q
F
A
R
S
Site 71
S932
S
G
R
Q
F
A
R
S
C
Y
Q
D
P
V
T
Site 72
Y934
R
Q
F
A
R
S
C
Y
Q
D
P
V
T
L
Q
Site 73
Y950
A
C
V
C
D
P
G
Y
I
G
S
R
C
D
D
Site 74
S960
S
R
C
D
D
C
A
S
G
Y
F
G
N
P
S
Site 75
Y962
C
D
D
C
A
S
G
Y
F
G
N
P
S
E
V
Site 76
S967
S
G
Y
F
G
N
P
S
E
V
G
G
S
C
Q
Site 77
T984
Q
C
H
N
N
I
D
T
T
D
P
E
A
C
D
Site 78
T994
P
E
A
C
D
K
E
T
G
R
C
L
K
C
L
Site 79
Y1016
C
Q
F
C
R
F
G
Y
Y
G
D
A
L
R
Q
Site 80
S1095
A
A
H
S
F
G
P
S
C
N
E
F
T
G
Q
Site 81
T1141
C
D
P
R
G
I
E
T
P
Q
C
D
Q
S
T
Site 82
Y1169
C
D
K
C
T
R
G
Y
S
G
V
F
P
D
C
Site 83
S1170
D
K
C
T
R
G
Y
S
G
V
F
P
D
C
T
Site 84
T1219
V
I
G
P
Y
R
E
T
V
D
S
V
E
R
K
Site 85
S1222
P
Y
R
E
T
V
D
S
V
E
R
K
V
S
E
Site 86
S1228
D
S
V
E
R
K
V
S
E
I
K
D
I
L
A
Site 87
S1237
I
K
D
I
L
A
Q
S
P
A
A
E
P
L
K
Site 88
T1261
E
K
L
I
K
D
V
T
E
M
M
A
Q
V
E
Site 89
S1272
A
Q
V
E
V
K
L
S
D
T
T
S
Q
S
N
Site 90
T1274
V
E
V
K
L
S
D
T
T
S
Q
S
N
S
T
Site 91
S1276
V
K
L
S
D
T
T
S
Q
S
N
S
T
A
K
Site 92
S1278
L
S
D
T
T
S
Q
S
N
S
T
A
K
E
L
Site 93
S1280
D
T
T
S
Q
S
N
S
T
A
K
E
L
D
S
Site 94
S1287
S
T
A
K
E
L
D
S
L
Q
T
E
A
E
S
Site 95
T1290
K
E
L
D
S
L
Q
T
E
A
E
S
L
D
N
Site 96
T1298
E
A
E
S
L
D
N
T
V
K
E
L
A
E
Q
Site 97
S1320
D
I
R
G
A
L
D
S
I
T
K
Y
F
Q
M
Site 98
T1322
R
G
A
L
D
S
I
T
K
Y
F
Q
M
S
L
Site 99
S1328
I
T
K
Y
F
Q
M
S
L
E
A
E
E
R
V
Site 100
T1339
E
E
R
V
N
A
S
T
T
E
P
N
S
T
V
Site 101
T1340
E
R
V
N
A
S
T
T
E
P
N
S
T
V
E
Site 102
S1344
A
S
T
T
E
P
N
S
T
V
E
Q
S
A
L
Site 103
T1345
S
T
T
E
P
N
S
T
V
E
Q
S
A
L
M
Site 104
S1365
D
V
M
M
E
R
E
S
Q
F
K
E
K
Q
E
Site 105
T1400
A
A
E
M
T
C
G
T
P
P
G
A
S
C
S
Site 106
S1405
C
G
T
P
P
G
A
S
C
S
E
T
E
C
G
Site 107
S1407
T
P
P
G
A
S
C
S
E
T
E
C
G
G
P
Site 108
T1409
P
G
A
S
C
S
E
T
E
C
G
G
P
N
C
Site 109
T1418
C
G
G
P
N
C
R
T
D
E
G
E
R
K
C
Site 110
S1453
D
L
D
Q
D
V
L
S
A
L
A
E
V
E
Q
Site 111
S1462
L
A
E
V
E
Q
L
S
K
M
V
S
E
A
K
Site 112
S1466
E
Q
L
S
K
M
V
S
E
A
K
L
R
A
D
Site 113
S1478
R
A
D
E
A
K
Q
S
A
E
D
I
L
L
K
Site 114
S1496
T
K
E
K
M
D
K
S
N
E
E
L
R
N
L
Site 115
T1512
K
Q
I
R
N
F
L
T
Q
D
S
A
D
L
D
Site 116
S1515
R
N
F
L
T
Q
D
S
A
D
L
D
S
I
E
Site 117
S1520
Q
D
S
A
D
L
D
S
I
E
A
V
A
N
E
Site 118
T1536
L
K
M
E
M
P
S
T
P
Q
Q
L
Q
N
L
Site 119
S1553
D
I
R
E
R
V
E
S
L
S
Q
V
E
V
I
Site 120
S1555
R
E
R
V
E
S
L
S
Q
V
E
V
I
L
Q
Site 121
S1582
L
E
E
A
K
R
A
S
K
S
A
T
D
V
K
Site 122
S1584
E
A
K
R
A
S
K
S
A
T
D
V
K
V
T
Site 123
T1586
K
R
A
S
K
S
A
T
D
V
K
V
T
A
D
Site 124
T1628
Q
G
T
Q
N
L
L
T
S
I
E
S
E
T
A
Site 125
S1629
G
T
Q
N
L
L
T
S
I
E
S
E
T
A
A
Site 126
S1637
I
E
S
E
T
A
A
S
E
E
T
L
F
N
A
Site 127
S1645
E
E
T
L
F
N
A
S
Q
R
I
S
E
L
E
Site 128
S1649
F
N
A
S
Q
R
I
S
E
L
E
R
N
V
E
Site 129
Y1677
E
Y
I
E
K
V
V
Y
T
V
K
Q
S
A
E
Site 130
T1678
Y
I
E
K
V
V
Y
T
V
K
Q
S
A
E
D
Site 131
T1689
S
A
E
D
V
K
K
T
L
D
G
E
L
D
E
Site 132
Y1698
D
G
E
L
D
E
K
Y
K
K
V
E
N
L
I
Site 133
S1735
T
L
L
A
Q
A
N
S
K
L
Q
L
L
K
D
Site 134
Y1747
L
K
D
L
E
R
K
Y
E
D
N
Q
R
Y
L
Site 135
Y1753
K
Y
E
D
N
Q
R
Y
L
E
D
K
A
Q
E
Site 136
S1770
R
L
E
G
E
V
R
S
L
L
K
D
I
S
Q
Site 137
S1776
R
S
L
L
K
D
I
S
Q
K
V
A
V
Y
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation