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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEACAM5
Full Name:
Carcinoembryonic antigen-related cell adhesion molecule 5
Alias:
Carcinoembryonic antigen;Meconium antigen 100
Type:
Mass (Da):
76796
Number AA:
702
UniProt ID:
P06731
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T32
L
T
F
W
N
P
P
T
T
A
K
L
T
I
E
Site 2
T37
P
P
T
T
A
K
L
T
I
E
S
T
P
F
N
Site 3
T41
A
K
L
T
I
E
S
T
P
F
N
V
A
E
G
Site 4
Y65
L
P
Q
H
L
F
G
Y
S
W
Y
K
G
E
R
Site 5
Y82
G
N
R
Q
I
I
G
Y
V
I
G
T
Q
Q
A
Site 6
T90
V
I
G
T
Q
Q
A
T
P
G
P
A
Y
S
G
Site 7
Y95
Q
A
T
P
G
P
A
Y
S
G
R
E
I
I
Y
Site 8
S96
A
T
P
G
P
A
Y
S
G
R
E
I
I
Y
P
Site 9
T121
Q
N
D
T
G
F
Y
T
L
H
V
I
K
S
D
Site 10
S127
Y
T
L
H
V
I
K
S
D
L
V
N
E
E
A
Site 11
Y141
A
T
G
Q
F
R
V
Y
P
E
L
P
K
P
S
Site 12
S148
Y
P
E
L
P
K
P
S
I
S
S
N
N
S
K
Site 13
S150
E
L
P
K
P
S
I
S
S
N
N
S
K
P
V
Site 14
S151
L
P
K
P
S
I
S
S
N
N
S
K
P
V
E
Site 15
S154
P
S
I
S
S
N
N
S
K
P
V
E
D
K
D
Site 16
T166
D
K
D
A
V
A
F
T
C
E
P
E
T
Q
D
Site 17
Y176
P
E
T
Q
D
A
T
Y
L
W
W
V
N
N
Q
Site 18
S184
L
W
W
V
N
N
Q
S
L
P
V
S
P
R
L
Site 19
S188
N
N
Q
S
L
P
V
S
P
R
L
Q
L
S
N
Site 20
S194
V
S
P
R
L
Q
L
S
N
G
N
R
T
L
T
Site 21
T199
Q
L
S
N
G
N
R
T
L
T
L
F
N
V
T
Site 22
T201
S
N
G
N
R
T
L
T
L
F
N
V
T
R
N
Site 23
T206
T
L
T
L
F
N
V
T
R
N
D
T
A
S
Y
Site 24
T210
F
N
V
T
R
N
D
T
A
S
Y
K
C
E
T
Site 25
S212
V
T
R
N
D
T
A
S
Y
K
C
E
T
Q
N
Site 26
Y213
T
R
N
D
T
A
S
Y
K
C
E
T
Q
N
P
Site 27
T217
T
A
S
Y
K
C
E
T
Q
N
P
V
S
A
R
Site 28
S222
C
E
T
Q
N
P
V
S
A
R
R
S
D
S
V
Site 29
S226
N
P
V
S
A
R
R
S
D
S
V
I
L
N
V
Site 30
T241
L
Y
G
P
D
A
P
T
I
S
P
L
N
T
S
Site 31
S243
G
P
D
A
P
T
I
S
P
L
N
T
S
Y
R
Site 32
T247
P
T
I
S
P
L
N
T
S
Y
R
S
G
E
N
Site 33
S248
T
I
S
P
L
N
T
S
Y
R
S
G
E
N
L
Site 34
S258
S
G
E
N
L
N
L
S
C
H
A
A
S
N
P
Site 35
S263
N
L
S
C
H
A
A
S
N
P
P
A
Q
Y
S
Site 36
T290
E
L
F
I
P
N
I
T
V
N
N
S
G
S
Y
Site 37
T298
V
N
N
S
G
S
Y
T
C
Q
A
H
N
S
D
Site 38
T312
D
T
G
L
N
R
T
T
V
T
T
I
T
V
Y
Site 39
T317
R
T
T
V
T
T
I
T
V
Y
A
E
P
P
K
Site 40
T328
E
P
P
K
P
F
I
T
S
N
N
S
N
P
V
Site 41
S329
P
P
K
P
F
I
T
S
N
N
S
N
P
V
E
Site 42
S332
P
F
I
T
S
N
N
S
N
P
V
E
D
E
D
Site 43
T344
D
E
D
A
V
A
L
T
C
E
P
E
I
Q
N
Site 44
S372
V
S
P
R
L
Q
L
S
N
D
N
R
T
L
T
Site 45
T377
Q
L
S
N
D
N
R
T
L
T
L
L
S
V
T
Site 46
T379
S
N
D
N
R
T
L
T
L
L
S
V
T
R
N
Site 47
S382
N
R
T
L
T
L
L
S
V
T
R
N
D
V
G
Site 48
S400
C
G
I
Q
N
E
L
S
V
D
H
S
D
P
V
Site 49
S404
N
E
L
S
V
D
H
S
D
P
V
I
L
N
V
Site 50
T419
L
Y
G
P
D
D
P
T
I
S
P
S
Y
T
Y
Site 51
S421
G
P
D
D
P
T
I
S
P
S
Y
T
Y
Y
R
Site 52
S423
D
D
P
T
I
S
P
S
Y
T
Y
Y
R
P
G
Site 53
Y424
D
P
T
I
S
P
S
Y
T
Y
Y
R
P
G
V
Site 54
T425
P
T
I
S
P
S
Y
T
Y
Y
R
P
G
V
N
Site 55
Y426
T
I
S
P
S
Y
T
Y
Y
R
P
G
V
N
L
Site 56
Y427
I
S
P
S
Y
T
Y
Y
R
P
G
V
N
L
S
Site 57
S434
Y
R
P
G
V
N
L
S
L
S
C
H
A
A
S
Site 58
S436
P
G
V
N
L
S
L
S
C
H
A
A
S
N
P
Site 59
S441
S
L
S
C
H
A
A
S
N
P
P
A
Q
Y
S
Site 60
T459
D
G
N
I
Q
Q
H
T
Q
E
L
F
I
S
N
Site 61
S465
H
T
Q
E
L
F
I
S
N
I
T
E
K
N
S
Site 62
T468
E
L
F
I
S
N
I
T
E
K
N
S
G
L
Y
Site 63
Y475
T
E
K
N
S
G
L
Y
T
C
Q
A
N
N
S
Site 64
T476
E
K
N
S
G
L
Y
T
C
Q
A
N
N
S
A
Site 65
S484
C
Q
A
N
N
S
A
S
G
H
S
R
T
T
V
Site 66
T490
A
S
G
H
S
R
T
T
V
K
T
I
T
V
S
Site 67
T493
H
S
R
T
T
V
K
T
I
T
V
S
A
E
L
Site 68
T495
R
T
T
V
K
T
I
T
V
S
A
E
L
P
K
Site 69
S504
S
A
E
L
P
K
P
S
I
S
S
N
N
S
K
Site 70
T522
D
K
D
A
V
A
F
T
C
E
P
E
A
Q
N
Site 71
Y532
P
E
A
Q
N
T
T
Y
L
W
W
V
N
G
Q
Site 72
S540
L
W
W
V
N
G
Q
S
L
P
V
S
P
R
L
Site 73
S544
N
G
Q
S
L
P
V
S
P
R
L
Q
L
S
N
Site 74
Y569
T
R
N
D
A
R
A
Y
V
C
G
I
Q
N
S
Site 75
S576
Y
V
C
G
I
Q
N
S
V
S
A
N
R
S
D
Site 76
S578
C
G
I
Q
N
S
V
S
A
N
R
S
D
P
V
Site 77
S582
N
S
V
S
A
N
R
S
D
P
V
T
L
D
V
Site 78
T586
A
N
R
S
D
P
V
T
L
D
V
L
Y
G
P
Site 79
T595
D
V
L
Y
G
P
D
T
P
I
I
S
P
P
D
Site 80
S599
G
P
D
T
P
I
I
S
P
P
D
S
S
Y
L
Site 81
S603
P
I
I
S
P
P
D
S
S
Y
L
S
G
A
N
Site 82
S604
I
I
S
P
P
D
S
S
Y
L
S
G
A
N
L
Site 83
Y605
I
S
P
P
D
S
S
Y
L
S
G
A
N
L
N
Site 84
S607
P
P
D
S
S
Y
L
S
G
A
N
L
N
L
S
Site 85
S614
S
G
A
N
L
N
L
S
C
H
S
A
S
N
P
Site 86
S619
N
L
S
C
H
S
A
S
N
P
S
P
Q
Y
S
Site 87
S622
C
H
S
A
S
N
P
S
P
Q
Y
S
W
R
I
Site 88
Y625
A
S
N
P
S
P
Q
Y
S
W
R
I
N
G
I
Site 89
S626
S
N
P
S
P
Q
Y
S
W
R
I
N
G
I
P
Site 90
T637
N
G
I
P
Q
Q
H
T
Q
V
L
F
I
A
K
Site 91
Y653
T
P
N
N
N
G
T
Y
A
C
F
V
S
N
L
Site 92
S671
R
N
N
S
I
V
K
S
I
T
V
S
A
S
G
Site 93
S677
K
S
I
T
V
S
A
S
G
T
S
P
G
L
S
Site 94
S680
T
V
S
A
S
G
T
S
P
G
L
S
A
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation