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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP5B
Full Name:
ATP synthase subunit beta, mitochondrial
Alias:
ATPB; EC 3.6.3.14
Type:
Enzyme, hydrolase, mitochondrial
Mass (Da):
56560
Number AA:
529
UniProt ID:
P06576
International Prot ID:
IPI00303476
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005743
GO:0005753
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0001525
GO:0006091
GO:0006139
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
S
G
A
L
R
R
L
T
P
S
A
S
L
P
P
Site 2
S23
A
L
R
R
L
T
P
S
A
S
L
P
P
A
Q
Site 3
S25
R
R
L
T
P
S
A
S
L
P
P
A
Q
L
L
Site 4
Y46
A
V
H
P
V
R
D
Y
A
A
Q
T
S
P
S
Site 5
S51
R
D
Y
A
A
Q
T
S
P
S
P
K
A
G
A
Site 6
S53
Y
A
A
Q
T
S
P
S
P
K
A
G
A
A
T
Site 7
T107
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
Site 8
T110
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
Site 9
T116
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
Site 10
S128
R
G
Q
K
V
L
D
S
G
A
P
I
K
I
P
Site 11
T140
K
I
P
V
G
P
E
T
L
G
R
I
M
N
V
Site 12
T160
D
E
R
G
P
I
K
T
K
Q
F
A
P
I
H
Site 13
T213
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
Site 14
Y230
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
Site 15
S231
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
Site 16
T240
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
Site 17
Y247
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
Site 18
Y269
T
S
K
V
A
L
V
Y
G
Q
M
N
E
P
P
Site 19
Y292
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
Site 20
T312
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
Site 21
S316
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
Site 22
Y331
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
Site 23
T347
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
Site 24
T348
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
Site 25
S356
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
Site 26
Y361
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
Site 27
T368
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
Site 28
Y395
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
Site 29
S403
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
Site 30
T404
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
Site 31
S405
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
Site 32
S415
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
Site 33
Y418
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
Site 34
Y431
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
Site 35
S433
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
Site 36
S447
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
Site 37
T453
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Site 38
S455
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
Site 39
S465
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
Site 40
T475
F
Q
V
A
E
V
F
T
G
H
M
G
K
L
V
Site 41
Y499
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
Site 42
Y508
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
Site 43
S528
D
K
L
A
E
E
H
S
S
_
_
_
_
_
_
Site 44
S529
K
L
A
E
E
H
S
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation