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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCCB
Full Name:
Propionyl-CoA carboxylase beta chain, mitochondrial
Alias:
Propanoyl-CoA:carbon dioxide ligase subunit beta
Type:
Mass (Da):
58216
Number AA:
539
UniProt ID:
P05166
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
A
A
V
R
S
L
C
S
Q
A
T
S
V
N
E
Site 2
S34
S
L
C
S
Q
A
T
S
V
N
E
R
I
E
N
Site 3
T45
R
I
E
N
K
R
R
T
A
L
L
G
G
G
Q
Site 4
T65
Q
H
K
R
G
K
L
T
A
R
E
R
I
S
L
Site 5
S71
L
T
A
R
E
R
I
S
L
L
L
D
P
G
S
Site 6
S82
D
P
G
S
F
V
E
S
D
M
F
V
E
H
R
Site 7
S106
K
N
K
F
P
G
D
S
V
V
T
G
R
G
R
Site 8
Y120
R
I
N
G
R
L
V
Y
V
F
S
Q
D
F
T
Site 9
S161
P
V
I
G
L
N
D
S
G
G
A
R
I
Q
E
Site 10
S172
R
I
Q
E
G
V
E
S
L
A
G
Y
A
D
I
Site 11
T214
S
P
A
L
T
D
F
T
F
M
V
K
D
T
S
Site 12
S233
T
G
P
D
V
V
K
S
V
T
N
E
D
V
T
Site 13
T240
S
V
T
N
E
D
V
T
Q
E
E
L
G
G
A
Site 14
T249
E
E
L
G
G
A
K
T
H
T
T
M
S
G
V
Site 15
T251
L
G
G
A
K
T
H
T
T
M
S
G
V
A
H
Site 16
T252
G
G
A
K
T
H
T
T
M
S
G
V
A
H
R
Site 17
S254
A
K
T
H
T
T
M
S
G
V
A
H
R
A
F
Site 18
Y277
N
L
R
D
F
F
N
Y
L
P
L
S
S
Q
D
Site 19
S281
F
F
N
Y
L
P
L
S
S
Q
D
P
A
P
V
Site 20
S282
F
N
Y
L
P
L
S
S
Q
D
P
A
P
V
R
Site 21
S295
V
R
E
C
H
D
P
S
D
R
L
V
P
E
L
Site 22
Y314
P
L
E
S
T
K
A
Y
N
M
V
D
I
I
H
Site 23
S322
N
M
V
D
I
I
H
S
V
V
D
E
R
E
F
Site 24
T351
F
A
R
M
N
G
R
T
V
G
I
V
G
N
Q
Site 25
S370
S
G
C
L
D
I
N
S
S
V
K
G
A
R
F
Site 26
Y405
L
P
G
T
A
Q
E
Y
G
G
I
I
R
H
G
Site 27
Y439
R
K
A
Y
G
G
A
Y
D
V
M
S
S
K
H
Site 28
S443
G
G
A
Y
D
V
M
S
S
K
H
L
C
G
D
Site 29
Y453
H
L
C
G
D
T
N
Y
A
W
P
T
A
E
I
Site 30
T511
D
I
I
Q
P
S
S
T
R
A
R
I
C
C
D
Site 31
S524
C
D
L
D
V
L
A
S
K
K
V
Q
R
P
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation