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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHGB
Full Name:
Secretogranin-1
Alias:
Chromogranin B; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; SG1; SgI
Type:
Secreted protein
Mass (Da):
78246
Number AA:
677
UniProt ID:
P05060
International Prot ID:
IPI00006601
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005179
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
V
G
L
A
A
V
N
S
M
P
V
D
N
R
N
Site 2
S46
E
V
L
S
N
A
L
S
K
S
S
A
P
P
I
Site 3
S48
L
S
N
A
L
S
K
S
S
A
P
P
I
T
P
Site 4
S49
S
N
A
L
S
K
S
S
A
P
P
I
T
P
E
Site 5
T54
K
S
S
A
P
P
I
T
P
E
C
R
Q
V
L
Site 6
T63
E
C
R
Q
V
L
K
T
S
R
K
D
V
K
D
Site 7
T79
E
T
T
E
N
E
N
T
K
F
E
V
R
L
L
Site 8
S93
L
R
D
P
A
D
A
S
E
A
H
E
S
S
S
Site 9
S98
D
A
S
E
A
H
E
S
S
S
R
G
E
A
G
Site 10
S99
A
S
E
A
H
E
S
S
S
R
G
E
A
G
A
Site 11
T120
Q
G
P
T
K
A
D
T
E
K
W
A
E
G
G
Site 12
S140
R
A
D
E
P
Q
W
S
L
Y
P
S
D
S
Q
Site 13
Y142
D
E
P
Q
W
S
L
Y
P
S
D
S
Q
V
S
Site 14
S144
P
Q
W
S
L
Y
P
S
D
S
Q
V
S
E
E
Site 15
S146
W
S
L
Y
P
S
D
S
Q
V
S
E
E
V
K
Site 16
S149
Y
P
S
D
S
Q
V
S
E
E
V
K
T
R
H
Site 17
T154
Q
V
S
E
E
V
K
T
R
H
S
E
K
S
Q
Site 18
S157
E
E
V
K
T
R
H
S
E
K
S
Q
R
E
D
Site 19
S160
K
T
R
H
S
E
K
S
Q
R
E
D
E
E
E
Site 20
Y173
E
E
E
E
G
E
N
Y
Q
K
G
E
R
G
E
Site 21
S182
K
G
E
R
G
E
D
S
S
E
E
K
H
L
E
Site 22
S183
G
E
R
G
E
D
S
S
E
E
K
H
L
E
E
Site 23
T194
H
L
E
E
P
G
E
T
Q
N
A
F
L
N
E
Site 24
T219
E
L
V
A
R
S
E
T
H
A
A
G
H
S
Q
Site 25
S225
E
T
H
A
A
G
H
S
Q
E
K
T
H
S
R
Site 26
T229
A
G
H
S
Q
E
K
T
H
S
R
E
K
S
S
Site 27
S231
H
S
Q
E
K
T
H
S
R
E
K
S
S
Q
E
Site 28
S235
K
T
H
S
R
E
K
S
S
Q
E
S
G
E
E
Site 29
S239
R
E
K
S
S
Q
E
S
G
E
E
A
G
S
Q
Site 30
S245
E
S
G
E
E
A
G
S
Q
E
N
H
P
Q
E
Site 31
S259
E
S
K
G
Q
P
R
S
Q
E
E
S
E
E
G
Site 32
S263
Q
P
R
S
Q
E
E
S
E
E
G
E
E
D
A
Site 33
T271
E
E
G
E
E
D
A
T
S
E
V
D
K
R
R
Site 34
S272
E
G
E
E
D
A
T
S
E
V
D
K
R
R
T
Site 35
T279
S
E
V
D
K
R
R
T
R
P
R
H
H
H
G
Site 36
S288
P
R
H
H
H
G
R
S
R
P
D
R
S
S
Q
Site 37
S293
G
R
S
R
P
D
R
S
S
Q
G
G
S
L
P
Site 38
S294
R
S
R
P
D
R
S
S
Q
G
G
S
L
P
S
Site 39
S298
D
R
S
S
Q
G
G
S
L
P
S
E
E
K
G
Site 40
S301
S
Q
G
G
S
L
P
S
E
E
K
G
H
P
Q
Site 41
S311
K
G
H
P
Q
E
E
S
E
E
S
N
V
S
M
Site 42
S314
P
Q
E
E
S
E
E
S
N
V
S
M
A
S
L
Site 43
S317
E
S
E
E
S
N
V
S
M
A
S
L
G
E
K
Site 44
S320
E
S
N
V
S
M
A
S
L
G
E
K
R
D
H
Site 45
T330
E
K
R
D
H
H
S
T
H
Y
R
A
S
E
E
Site 46
Y332
R
D
H
H
S
T
H
Y
R
A
S
E
E
E
P
Site 47
S335
H
S
T
H
Y
R
A
S
E
E
E
P
E
Y
G
Site 48
Y341
A
S
E
E
E
P
E
Y
G
E
E
I
K
G
Y
Site 49
Y348
Y
G
E
E
I
K
G
Y
P
G
V
Q
A
P
E
Site 50
Y362
E
D
L
E
W
E
R
Y
R
G
R
G
S
E
E
Site 51
S367
E
R
Y
R
G
R
G
S
E
E
Y
R
A
P
R
Site 52
Y370
R
G
R
G
S
E
E
Y
R
A
P
R
P
Q
S
Site 53
S377
Y
R
A
P
R
P
Q
S
E
E
S
W
D
E
E
Site 54
S380
P
R
P
Q
S
E
E
S
W
D
E
E
D
K
R
Site 55
Y389
D
E
E
D
K
R
N
Y
P
S
L
E
L
D
K
Site 56
Y401
L
D
K
M
A
H
G
Y
G
E
E
S
E
E
E
Site 57
S405
A
H
G
Y
G
E
E
S
E
E
E
R
G
L
E
Site 58
Y429
R
G
G
E
P
R
A
Y
F
M
S
D
T
R
E
Site 59
S432
E
P
R
A
Y
F
M
S
D
T
R
E
E
K
R
Site 60
T434
R
A
Y
F
M
S
D
T
R
E
E
K
R
F
L
Site 61
Y471
W
K
E
L
D
R
N
Y
L
N
Y
G
E
E
G
Site 62
Y474
L
D
R
N
Y
L
N
Y
G
E
E
G
A
P
G
Site 63
Y506
A
R
F
Q
D
K
Q
Y
S
S
H
H
T
A
E
Site 64
S507
R
F
Q
D
K
Q
Y
S
S
H
H
T
A
E
K
Site 65
Y525
L
G
E
L
F
N
P
Y
Y
D
P
L
Q
W
K
Site 66
Y526
G
E
L
F
N
P
Y
Y
D
P
L
Q
W
K
S
Site 67
S533
Y
D
P
L
Q
W
K
S
S
H
F
E
R
R
D
Site 68
T556
G
E
E
E
N
E
L
T
L
N
E
K
N
F
F
Site 69
Y584
S
E
D
V
N
W
G
Y
E
K
R
N
L
A
R
Site 70
Y601
K
L
D
L
K
R
Q
Y
D
R
V
A
Q
L
D
Site 71
Y613
Q
L
D
Q
L
L
H
Y
R
K
K
S
A
E
F
Site 72
S617
L
L
H
Y
R
K
K
S
A
E
F
P
D
F
Y
Site 73
Y624
S
A
E
F
P
D
F
Y
D
S
E
E
P
V
S
Site 74
S626
E
F
P
D
F
Y
D
S
E
E
P
V
S
T
H
Site 75
S631
Y
D
S
E
E
P
V
S
T
H
Q
E
A
E
N
Site 76
T646
E
K
D
R
A
D
Q
T
V
L
T
E
D
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation