PhosphoNET

           
Protein Info 
   
Short Name:  CYP1A1
Full Name:  Cytochrome P450 1A1
Alias:  AHH; AHRR; Aryl hydrocarbon hydroxylase; CP11; CP1A1; CYP1; CYPIA1; Cytochrome P1-450, dioxin-inducible; Cytochrome P450 1A1 variant; Cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; Flavoprotein-linked monooxygenase; Microsomal monooxygenase; P1-450; P450 form 6; P450-C; P450DX; P450-P1; Xenobiotic monooxygenase
Type:  EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase; Amino Acid Metabolism - tryptophan; Cofactor and Vitamin Metabolism - retinol
Mass (Da):  58165
Number AA:  512
UniProt ID:  P04798
International Prot ID:  IPI00218839
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0019898  GO:0005792 Uniprot OncoNet
Molecular Function:  GO:0070330  GO:0009055  GO:0020037 PhosphoSite+ KinaseNET
Biological Process:  GO:0017144  GO:0055114  GO:0042359 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S29VFWVIRASRPQVPKG
Site 2S64KNPHLALSRMSQQYG
Site 3S67HLALSRMSQQYGDVL
Site 4Y70LSRMSQQYGDVLQIR
Site 5Y110FKGRPDLYTFTLISN
Site 6T111KGRPDLYTFTLISNG
Site 7T113RPDLYTFTLISNGQS
Site 8S120TLISNGQSMSFSPDS
Site 9S122ISNGQSMSFSPDSGP
Site 10S124NGQSMSFSPDSGPVW
Site 11S127SMSFSPDSGPVWAAR
Site 12S144LAQNGLKSFSIASDP
Site 13S146QNGLKSFSIASDPAS
Site 14S149LKSFSIASDPASSTS
Site 15S153SIASDPASSTSCYLE
Site 16S154IASDPASSTSCYLEE
Site 17S156SDPASSTSCYLEEHV
Site 18Y158PASSTSCYLEEHVSK
Site 19Y187GPGHFNPYRYVVVSV
Site 20Y189GHFNPYRYVVVSVTN
Site 21Y207AICFGRRYDHNHQEL
Site 22S216HNHQELLSLVNLNNN
Site 23Y242DFIPILRYLPNPSLN
Site 24S247LRYLPNPSLNAFKDL
Site 25T272MVKEHYKTFEKGHIR
Site 26T282KGHIRDITDSLIEHC
Site 27S284HIRDITDSLIEHCQE
Site 28S303ENANVQLSDEKIINI
Site 29T349KIQEELDTVIGRSRR
Site 30S354LDTVIGRSRRPRLSD
Site 31S360RSRRPRLSDRSHLPY
Site 32S363RPRLSDRSHLPYMEA
Site 33Y367SDRSHLPYMEAFILE
Site 34T385HSSFVPFTIPHSTTR
Site 35S389VPFTIPHSTTRDTSL
Site 36T390PFTIPHSTTRDTSLK
Site 37T394PHSTTRDTSLKGFYI
Site 38S395HSTTRDTSLKGFYIP
Site 39S425QKLWVNPSEFLPERF
Site 40T434FLPERFLTPDGAIDK
Site 41Y494KVDMTPIYGLTMKHA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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