PhosphoNET

           
Protein Info 
   
Short Name:  KRT6B
Full Name:  Keratin, type II cytoskeletal 6B
Alias:  CK 6B; Cytokeratin-6B; K2C6B; K6B; K6b keratin; Keratin; Keratin 6B; KRTL1
Type:  Keratin filmament protein
Mass (Da):  60067
Number AA:  564
UniProt ID:  P04259
International Prot ID:  IPI00293665
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0045095     Uniprot OncoNet
Molecular Function:  GO:0005200     PhosphoSite+ KinaseNET
Biological Process:  GO:0007398     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T6__MASTSTTIRSHSS
Site 2T7_MASTSTTIRSHSSS
Site 3S10STSTTIRSHSSSRRG
Site 4S12STTIRSHSSSRRGFS
Site 5S13TTIRSHSSSRRGFSA
Site 6S14TIRSHSSSRRGFSAN
Site 7S19SSSRRGFSANSARLP
Site 8S22RRGFSANSARLPGVS
Site 9S29SARLPGVSRSGFSSI
Site 10S31RLPGVSRSGFSSISV
Site 11S34GVSRSGFSSISVSRS
Site 12S35VSRSGFSSISVSRSR
Site 13S37RSGFSSISVSRSRGS
Site 14S39GFSSISVSRSRGSGG
Site 15S41SSISVSRSRGSGGLG
Site 16S44SVSRSRGSGGLGGAC
Site 17S58CGGAGFGSRSLYGLG
Site 18S60GAGFGSRSLYGLGGS
Site 19Y62GFGSRSLYGLGGSKR
Site 20S67SLYGLGGSKRISIGG
Site 21S71LGGSKRISIGGGSCA
Site 22S76RISIGGGSCAISGGY
Site 23S80GGGSCAISGGYGSRA
Site 24Y83SCAISGGYGSRAGGS
Site 25S85AISGGYGSRAGGSYG
Site 26S90YGSRAGGSYGFGGAG
Site 27Y91GSRAGGSYGFGGAGS
Site 28T169EEREQIKTLNNKFAS
Site 29S176TLNNKFASFIDKVRF
Site 30T205LQEQGTKTVRQNLEP
Site 31S237GERGRLDSELRNMQD
Site 32Y253VEDLKNKYEDEINKR
Site 33Y278KKDVDAAYMNKVELQ
Site 34T290ELQAKADTLTDEINF
Site 35T292QAKADTLTDEINFLR
Site 36S307ALYDAELSQMQTHIS
Site 37T311AELSQMQTHISDTSV
Site 38S314SQMQTHISDTSVVLS
Site 39S317QTHISDTSVVLSMDN
Site 40S321SDTSVVLSMDNNRNL
Site 41S332NRNLDLDSIIAEVKA
Site 42Y341IAEVKAQYEEIAQRS
Site 43S348YEEIAQRSRAEAESW
Site 44S354RSRAEAESWYQTKYE
Site 45Y356RAEAESWYQTKYEEL
Site 46T358EAESWYQTKYEELQI
Site 47Y360ESWYQTKYEELQVTA
Site 48T366KYEELQITAGRHGDD
Site 49T377HGDDLRNTKQEIAEI
Site 50S393RMIQRLRSEIDHVKK
Site 51Y448LARLLKEYQELMNVK
Site 52Y465LDVEIATYRKLLEGE
Site 53T492NISVVQSTVSSGYGG
Site 54S494SVVQSTVSSGYGGAS
Site 55S501SSGYGGASGVGSGLG
Site 56S513GLGLGGGSSYSYGSG
Site 57S514LGLGGGSSYSYGSGL
Site 58Y515GLGGGSSYSYGSGLG
Site 59S516LGGGSSYSYGSGLGV
Site 60Y517GGGSSYSYGSGLGVG
Site 61S519GSSYSYGSGLGVGGG
Site 62S528LGVGGGFSSSSGRAT
Site 63S529GVGGGFSSSSGRATG
Site 64S530VGGGFSSSSGRATGG
Site 65S531GGGFSSSSGRATGGG
Site 66T535SSSSGRATGGGLSSV
Site 67S540RATGGGLSSVGGGSS
Site 68S541ATGGGLSSVGGGSST
Site 69S547SSVGGGSSTIKYTTT
Site 70T548SVGGGSSTIKYTTTS
Site 71Y551GGSSTIKYTTTSSSS
Site 72T552GSSTIKYTTTSSSSR
Site 73T553SSTIKYTTTSSSSRK
Site 74T554STIKYTTTSSSSRKS
Site 75S555TIKYTTTSSSSRKSY
Site 76S556IKYTTTSSSSRKSYK
Site 77S557KYTTTSSSSRKSYKH
Site 78S558YTTTSSSSRKSYKH_
Site 79S561TSSSSRKSYKH____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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