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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OAT
Full Name:
Ornithine aminotransferase, mitochondrial
Alias:
EC 2.6.1.13; HOGA; Ornithine aminotransferase (gyrate atrophy); Ornithine--oxo-acid aminotransferase
Type:
Enzyme - Aminotransferase
Mass (Da):
48535
Number AA:
439
UniProt ID:
P04181
International Prot ID:
IPI00022334
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005759
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004587
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0003008
GO:0007600
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
T
S
V
A
T
K
K
T
V
Q
G
P
P
T
S
Site 2
S40
T
V
Q
G
P
P
T
S
D
D
I
F
E
R
E
Site 3
Y48
D
D
I
F
E
R
E
Y
K
Y
G
A
H
N
Y
Site 4
Y50
I
F
E
R
E
Y
K
Y
G
A
H
N
Y
H
P
Site 5
Y69
L
E
R
G
K
G
I
Y
L
W
D
V
E
G
R
Site 6
Y78
W
D
V
E
G
R
K
Y
F
D
F
L
S
S
Y
Site 7
S83
R
K
Y
F
D
F
L
S
S
Y
S
A
V
N
Q
Site 8
S84
K
Y
F
D
F
L
S
S
Y
S
A
V
N
Q
G
Site 9
Y85
Y
F
D
F
L
S
S
Y
S
A
V
N
Q
G
H
Site 10
T109
K
S
Q
V
D
K
L
T
L
T
S
R
A
F
Y
Site 11
T111
Q
V
D
K
L
T
L
T
S
R
A
F
Y
N
N
Site 12
Y116
T
L
T
S
R
A
F
Y
N
N
V
L
G
E
Y
Site 13
Y126
V
L
G
E
Y
E
E
Y
I
T
K
L
F
N
Y
Site 14
Y133
Y
I
T
K
L
F
N
Y
H
K
V
L
P
M
N
Site 15
T148
T
G
V
E
A
G
E
T
A
C
K
L
A
R
K
Site 16
Y158
K
L
A
R
K
W
G
Y
T
V
K
G
I
Q
K
Site 17
T159
L
A
R
K
W
G
Y
T
V
K
G
I
Q
K
Y
Site 18
Y166
T
V
K
G
I
Q
K
Y
K
A
K
I
V
F
A
Site 19
T181
A
G
N
F
W
G
R
T
L
S
A
I
S
S
S
Site 20
S183
N
F
W
G
R
T
L
S
A
I
S
S
S
T
D
Site 21
S186
G
R
T
L
S
A
I
S
S
S
T
D
P
T
S
Site 22
S187
R
T
L
S
A
I
S
S
S
T
D
P
T
S
Y
Site 23
S188
T
L
S
A
I
S
S
S
T
D
P
T
S
Y
D
Site 24
T189
L
S
A
I
S
S
S
T
D
P
T
S
Y
D
G
Site 25
T192
I
S
S
S
T
D
P
T
S
Y
D
G
F
G
P
Site 26
S193
S
S
S
T
D
P
T
S
Y
D
G
F
G
P
F
Site 27
Y194
S
S
T
D
P
T
S
Y
D
G
F
G
P
F
M
Site 28
Y245
V
V
V
P
D
P
G
Y
L
M
G
V
R
E
L
Site 29
T272
I
Q
T
G
L
A
R
T
G
R
W
L
A
V
D
Site 30
Y280
G
R
W
L
A
V
D
Y
E
N
V
R
P
D
I
Site 31
S321
I
K
P
G
E
H
G
S
T
Y
G
G
N
P
L
Site 32
T322
K
P
G
E
H
G
S
T
Y
G
G
N
P
L
G
Site 33
Y323
P
G
E
H
G
S
T
Y
G
G
N
P
L
G
C
Site 34
T369
K
L
P
S
D
V
V
T
A
V
R
G
K
G
L
Site 35
S428
K
E
D
E
L
R
E
S
I
E
I
I
N
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation