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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANXA1
Full Name:
Annexin A1
Alias:
Annexin I; Annexin-1; ANX1; Calpactin II; Chromobindin 9; Chromobindin-9; Lipocortin I; LPC1; LPC-1; P35; Phospholipase A2 inhibitory protein
Type:
Lipid binding protein; Calcium-binding protein
Mass (Da):
38714
Number AA:
346
UniProt ID:
P04083
International Prot ID:
IPI00218918
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016323
GO:0005929
GO:0001533
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005544
GO:0019834
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0007166
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Annexin A1 Y207 phosphosite-specific antibody AB-PN503#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN503#Annexin A1 (R204-G210, human) pY207 phosphopeptide - Powder PE-04AEY95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEY95#Annexin A1 (A203-G210, human) pY207 phosphopeptide - Powder PE-04ARB95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARB95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
_
A
M
V
S
E
F
L
K
Q
A
W
Site 2
Y21
I
E
N
E
E
Q
E
Y
V
Q
T
V
K
S
S
Site 3
T24
E
E
Q
E
Y
V
Q
T
V
K
S
S
K
G
G
Site 4
S27
E
Y
V
Q
T
V
K
S
S
K
G
G
P
G
S
Site 5
S28
Y
V
Q
T
V
K
S
S
K
G
G
P
G
S
A
Site 6
S34
S
S
K
G
G
P
G
S
A
V
S
P
Y
P
T
Site 7
S37
G
G
P
G
S
A
V
S
P
Y
P
T
F
N
P
Site 8
Y39
P
G
S
A
V
S
P
Y
P
T
F
N
P
S
S
Site 9
T41
S
A
V
S
P
Y
P
T
F
N
P
S
S
D
V
Site 10
S45
P
Y
P
T
F
N
P
S
S
D
V
A
A
L
H
Site 11
S46
Y
P
T
F
N
P
S
S
D
V
A
A
L
H
K
Site 12
T64
V
K
G
V
D
E
A
T
I
I
D
I
L
T
K
Site 13
T70
A
T
I
I
D
I
L
T
K
R
N
N
A
Q
R
Site 14
Y84
R
Q
Q
I
K
A
A
Y
L
Q
E
T
G
K
P
Site 15
T88
K
A
A
Y
L
Q
E
T
G
K
P
L
D
E
T
Site 16
T95
T
G
K
P
L
D
E
T
L
K
K
A
L
T
G
Site 17
S143
T
L
I
E
I
L
A
S
R
T
N
K
E
I
R
Site 18
Y156
I
R
D
I
N
R
V
Y
R
E
E
L
K
R
D
Site 19
T169
R
D
L
A
K
D
I
T
S
D
T
S
G
D
F
Site 20
S170
D
L
A
K
D
I
T
S
D
T
S
G
D
F
R
Site 21
T172
A
K
D
I
T
S
D
T
S
G
D
F
R
N
A
Site 22
S173
K
D
I
T
S
D
T
S
G
D
F
R
N
A
L
Site 23
S182
D
F
R
N
A
L
L
S
L
A
K
G
D
R
S
Site 24
S189
S
L
A
K
G
D
R
S
E
D
F
G
V
N
E
Site 25
S201
V
N
E
D
L
A
D
S
D
A
R
A
L
Y
E
Site 26
Y207
D
S
D
A
R
A
L
Y
E
A
G
E
R
R
K
Annexin A1 Y207 phosphosite-specific antibody AB-PN503#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN503#Annexin A1 (R204-G210, human) pY207 phosphopeptide - Powder PE-04AEY95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEY95#Annexin A1 (A203-G210, human) pY207 phosphopeptide - Powder PE-04ARB95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04ARB95
Site 27
T216
A
G
E
R
R
K
G
T
D
V
N
V
F
N
T
Site 28
T226
N
V
F
N
T
I
L
T
T
R
S
Y
P
Q
L
Site 29
Y230
T
I
L
T
T
R
S
Y
P
Q
L
R
R
V
F
Site 30
Y240
L
R
R
V
F
Q
K
Y
T
K
Y
S
K
H
D
Site 31
Y243
V
F
Q
K
Y
T
K
Y
S
K
H
D
M
N
K
Site 32
T272
T
A
I
V
K
C
A
T
S
K
P
A
F
F
A
Site 33
S304
I
R
I
M
V
S
R
S
E
I
D
M
N
D
I
Site 34
Y315
M
N
D
I
K
A
F
Y
Q
K
M
Y
G
I
S
Site 35
Y335
L
D
E
T
K
G
D
Y
E
K
I
L
V
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation