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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FUCA1
Full Name:
Tissue alpha-L-fucosidase
Alias:
alpha-L-fucosidase; alpha-L-fucosidase I; alpha-L-fucoside fucohydrolase; FUCO; fucosidase, alpha-L- 1, tissue; Nbla10230/alpha-L-fucosidase; tissue alpha-L-fucosidase
Type:
EC 3.2.1.51; Hydrolase; Glycan Metabolism - other glycan degradation
Mass (Da):
53689
Number AA:
461
UniProt ID:
P04066
International Prot ID:
IPI00745745
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005764
Uniprot
OncoNet
Molecular Function:
GO:0004560
PhosphoSite+
KinaseNET
Biological Process:
GO:0006004
GO:0006027
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
R
A
P
G
M
R
S
R
P
A
G
P
A
L
Site 2
S27
L
F
L
G
A
A
E
S
V
R
R
A
Q
P
P
Site 3
Y37
R
A
Q
P
P
R
R
Y
T
P
D
W
P
S
L
Site 4
T38
A
Q
P
P
R
R
Y
T
P
D
W
P
S
L
D
Site 5
S43
R
Y
T
P
D
W
P
S
L
D
S
R
P
L
P
Site 6
S46
P
D
W
P
S
L
D
S
R
P
L
P
A
W
F
Site 7
Y89
Q
G
E
G
R
P
Q
Y
Q
R
F
M
R
D
N
Site 8
Y97
Q
R
F
M
R
D
N
Y
P
P
G
F
S
Y
A
Site 9
S102
D
N
Y
P
P
G
F
S
Y
A
D
F
G
P
Q
Site 10
Y103
N
Y
P
P
G
F
S
Y
A
D
F
G
P
Q
F
Site 11
T111
A
D
F
G
P
Q
F
T
A
R
F
F
H
P
E
Site 12
T143
T
K
H
H
E
G
F
T
N
W
P
S
P
V
S
Site 13
T170
D
L
V
G
E
L
G
T
A
L
R
K
R
N
I
Site 14
Y182
R
N
I
R
Y
G
L
Y
H
S
L
L
E
W
F
Site 15
Y193
L
E
W
F
H
P
L
Y
L
L
D
K
K
N
G
Site 16
T203
D
K
K
N
G
F
K
T
Q
H
F
V
S
A
K
Site 17
S208
F
K
T
Q
H
F
V
S
A
K
T
M
P
E
L
Site 18
Y216
A
K
T
M
P
E
L
Y
D
L
V
N
S
Y
K
Site 19
S253
L
S
W
L
Y
N
D
S
P
V
K
D
E
V
V
Site 20
Y277
S
C
H
H
G
G
Y
Y
N
C
E
D
K
F
K
Site 21
S287
E
D
K
F
K
P
Q
S
L
P
D
H
K
W
E
Site 22
Y306
I
D
K
F
S
W
G
Y
R
R
D
M
A
L
S
Site 23
S313
Y
R
R
D
M
A
L
S
D
V
T
E
E
S
E
Site 24
T316
D
M
A
L
S
D
V
T
E
E
S
E
I
I
S
Site 25
S323
T
E
E
S
E
I
I
S
E
L
V
Q
T
V
S
Site 26
Y370
S
I
N
G
E
A
I
Y
A
S
K
P
W
R
V
Site 27
Y388
K
N
T
T
S
V
W
Y
T
S
K
G
S
A
V
Site 28
T389
N
T
T
S
V
W
Y
T
S
K
G
S
A
V
Y
Site 29
S412
N
G
V
L
N
L
E
S
P
I
T
T
S
T
T
Site 30
T415
L
N
L
E
S
P
I
T
T
S
T
T
K
I
T
Site 31
S433
I
Q
G
D
L
K
W
S
T
D
P
D
K
G
L
Site 32
T434
Q
G
D
L
K
W
S
T
D
P
D
K
G
L
F
Site 33
S443
P
D
K
G
L
F
I
S
L
P
Q
L
P
P
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation