KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
APCS
Full Name:
Serum amyloid P-component
Alias:
9.5S alpha-1-glycoprotein; Amyloid P component, serum; MGC88159; Pentaxin-related; PTX2; SAMP; SAP; Serum amyloid P component
Type:
Chaperone
Mass (Da):
25387
Number AA:
223
UniProt ID:
P02743
International Prot ID:
IPI00022391
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005529
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006953
GO:0051131
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T43
T
D
H
V
N
L
I
T
P
L
E
K
P
L
Q
Site 2
T53
E
K
P
L
Q
N
F
T
L
C
F
R
A
Y
S
Site 3
Y59
F
T
L
C
F
R
A
Y
S
D
L
S
R
A
Y
Site 4
S60
T
L
C
F
R
A
Y
S
D
L
S
R
A
Y
S
Site 5
S63
F
R
A
Y
S
D
L
S
R
A
Y
S
L
F
S
Site 6
Y66
Y
S
D
L
S
R
A
Y
S
L
F
S
Y
N
T
Site 7
S67
S
D
L
S
R
A
Y
S
L
F
S
Y
N
T
Q
Site 8
Y71
R
A
Y
S
L
F
S
Y
N
T
Q
G
R
D
N
Site 9
Y83
R
D
N
E
L
L
V
Y
K
E
R
V
G
E
Y
Site 10
S91
K
E
R
V
G
E
Y
S
L
Y
I
G
R
H
K
Site 11
Y93
R
V
G
E
Y
S
L
Y
I
G
R
H
K
V
T
Site 12
S101
I
G
R
H
K
V
T
S
K
V
I
E
K
F
P
Site 13
Y142
K
K
G
L
R
Q
G
Y
F
V
E
A
Q
P
K
Site 14
S158
V
L
G
Q
E
Q
D
S
Y
G
G
K
F
D
R
Site 15
Y159
L
G
Q
E
Q
D
S
Y
G
G
K
F
D
R
S
Site 16
S166
Y
G
G
K
F
D
R
S
Q
S
F
V
G
E
I
Site 17
S168
G
K
F
D
R
S
Q
S
F
V
G
E
I
G
D
Site 18
S190
L
P
P
E
N
I
L
S
A
Y
Q
G
T
P
L
Site 19
Y209
L
D
W
Q
A
L
N
Y
E
I
R
G
Y
V
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation