PhosphoNET

           
Protein Info 
   
Short Name:  GH2
Full Name:  Growth hormone variant
Alias:  Growth hormone 2;Placenta-specific growth hormone
Type:  Secreted protein
Mass (Da):  25000
Number AA:  217
UniProt ID:  P01242
International Prot ID:  IPI00000890
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576     Uniprot OncoNet
Molecular Function:  GO:0005179     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T29QEGSAFPTIPLSRLF
Site 2Y47MLRARRLYQLAYDTY
Site 3Y51RRLYQLAYDTYQEFE
Site 4Y54YQLAYDTYQEFEEAY
Site 5Y68YILKEQKYSFLQNPQ
Site 6S69ILKEQKYSFLQNPQT
Site 7T76SFLQNPQTSLCFSES
Site 8S77FLQNPQTSLCFSESI
Site 9S81PQTSLCFSESIPTPS
Site 10S83TSLCFSESIPTPSNR
Site 11T86CFSESIPTPSNRVKT
Site 12S88SESIPTPSNRVKTQQ
Site 13T93TPSNRVKTQQKSNLE
Site 14S97RVKTQQKSNLELLRI
Site 15S132NSLVYGASDSNVYRH
Site 16S134LVYGASDSNVYRHLK
Site 17T149DLEEGIQTLMWRLED
Site 18S158MWRLEDGSPRTGQIF
Site 19S168TGQIFNQSYSKFDTK
Site 20S170QIFNQSYSKFDTKSH
Site 21T174QSYSKFDTKSHNDDA
Site 22S176YSKFDTKSHNDDALL
Site 23Y190LKNYGLLYCFRKDMD
Site 24T201KDMDKVETFLRIVQC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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