PhosphoNET

           
Protein Info 
   
Short Name:  GH
Full Name:  Somatotropin
Alias:  Growth hormone;Growth hormone 1;Pituitary growth hormone
Type:  Ligand, extracellular
Mass (Da):  24847
Number AA:  217
UniProt ID:  P01241
International Prot ID:  IPI00000889
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615     Uniprot OncoNet
Molecular Function:  GO:0008083  GO:0070186  GO:0005131 PhosphoSite+ KinaseNET
Biological Process:  GO:0007259  GO:0015758  GO:0060396 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T29QEGSAFPTIPLSRLF
Site 2T53LHQLAFDTYQEFEEA
Site 3Y54HQLAFDTYQEFEEAY
Site 4Y68YIPKEQKYSFLQNPQ
Site 5S69IPKEQKYSFLQNPQT
Site 6T76SFLQNPQTSLCFSES
Site 7S77FLQNPQTSLCFSESI
Site 8S81PQTSLCFSESIPTPS
Site 9S83TSLCFSESIPTPSNR
Site 10T86CFSESIPTPSNREET
Site 11S88SESIPTPSNREETQQ
Site 12T93TPSNREETQQKSNLE
Site 13S97REETQQKSNLELLRI
Site 14S132NSLVYGASDSNVYDL
Site 15T149DLEEGIQTLMGRLED
Site 16S158MGRLEDGSPRTGQIF
Site 17T168TGQIFKQTYSKFDTN
Site 18T174QTYSKFDTNSHNDDA
Site 19S176YSKFDTNSHNDDALL
Site 20Y190LKNYGLLYCFRKDMD
Site 21T201KDMDKVETFLRIVQC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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