PhosphoNET

           
Protein Info 
   
Short Name:  EGF
Full Name:  Pro-epidermal growth factor
Alias:  Beta-urogastrone; Epidermal growth factor
Type: 
Mass (Da):  133950
Number AA: 
UniProt ID:  P01133
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886  GO:0031093 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005154  GO:0008083 PhosphoSite+ KinaseNET
Biological Process:  GO:0006260  GO:0001525  GO:0051048 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19VSKFSFVSLSAPQHW
Site 2S21KFSFVSLSAPQHWSC
Site 3S262FGDRIFYSTWKMKTI
Site 4S348CAEGYALSRDRKYCE
Site 5Y1056LSLWGAHYYRTQKLL
Site 6Y1057SLWGAHYYRTQKLLS
Site 7S1064YRTQKLLSKNPKNPY
Site 8Y1071SKNPKNPYEESSRDV
Site 9S1074PKNPYEESSRDVRSR
Site 10S1075KNPYEESSRDVRSRR
Site 11S1080ESSRDVRSRRPADTE
Site 12T1086RSRRPADTEDGMSSC
Site 13S1125DGQAADGSMQPTSWR
Site 14T1129ADGSMQPTSWRQEPQ
Site 15S1130DGSMQPTSWRQEPQL
Site 16S1151QGCWIPVSSDKGSCP
Site 17S1152GCWIPVSSDKGSCPQ
Site 18S1156PVSSDKGSCPQVMER
Site 19S1169ERSFHMPSYGTQTLE
Site 20Y1170RSFHMPSYGTQTLEG
Site 21S1184GGVEKPHSLLSANPL
Site 22S1187EKPHSLLSANPLWQQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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