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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
F10
Full Name:
Coagulation factor X
Alias:
Stuart factor;Stuart-Prower factor
Type:
Mass (Da):
54732
Number AA:
488
UniProt ID:
P00742
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T39
N
N
I
L
A
R
V
T
R
A
N
S
F
L
E
Site 2
S43
A
R
V
T
R
A
N
S
F
L
E
E
M
K
K
Site 3
S63
E
C
M
E
E
T
C
S
Y
E
E
A
R
E
V
Site 4
Y64
C
M
E
E
T
C
S
Y
E
E
A
R
E
V
F
Site 5
S74
A
R
E
V
F
E
D
S
D
K
T
N
E
F
W
Site 6
Y84
T
N
E
F
W
N
K
Y
K
D
G
D
Q
C
E
Site 7
S93
D
G
D
Q
C
E
T
S
P
C
Q
N
Q
G
K
Site 8
Y108
C
K
D
G
L
G
E
Y
T
C
T
C
L
E
G
Site 9
S130
L
F
T
R
K
L
C
S
L
D
N
G
D
C
D
Site 10
S150
E
Q
N
S
V
V
C
S
C
A
R
G
Y
T
L
Site 11
Y155
V
C
S
C
A
R
G
Y
T
L
A
D
N
G
K
Site 12
T156
C
S
C
A
R
G
Y
T
L
A
D
N
G
K
A
Site 13
Y170
A
C
I
P
T
G
P
Y
P
C
G
K
Q
T
L
Site 14
T176
P
Y
P
C
G
K
Q
T
L
E
R
R
K
R
S
Site 15
S183
T
L
E
R
R
K
R
S
V
A
Q
A
T
S
S
Site 16
S189
R
S
V
A
Q
A
T
S
S
S
G
E
A
P
D
Site 17
S190
S
V
A
Q
A
T
S
S
S
G
E
A
P
D
S
Site 18
S197
S
S
G
E
A
P
D
S
I
T
W
K
P
Y
D
Site 19
T199
G
E
A
P
D
S
I
T
W
K
P
Y
D
A
A
Site 20
T211
D
A
A
D
L
D
P
T
E
N
P
F
D
L
L
Site 21
T233
E
R
G
D
N
N
L
T
R
I
V
G
G
Q
E
Site 22
T293
V
R
V
G
D
R
N
T
E
Q
E
E
G
G
E
Site 23
S351
P
E
R
D
W
A
E
S
T
L
M
T
Q
K
T
Site 24
T355
W
A
E
S
T
L
M
T
Q
K
T
G
I
V
S
Site 25
S362
T
Q
K
T
G
I
V
S
G
F
G
R
T
H
E
Site 26
S374
T
H
E
K
G
R
Q
S
T
R
L
K
M
L
E
Site 27
T375
H
E
K
G
R
Q
S
T
R
L
K
M
L
E
V
Site 28
Y384
L
K
M
L
E
V
P
Y
V
D
R
N
S
C
K
Site 29
S389
V
P
Y
V
D
R
N
S
C
K
L
S
S
S
F
Site 30
S393
D
R
N
S
C
K
L
S
S
S
F
I
I
T
Q
Site 31
S395
N
S
C
K
L
S
S
S
F
I
I
T
Q
N
M
Site 32
Y452
R
K
G
K
Y
G
I
Y
T
K
V
T
A
F
L
Site 33
S476
R
G
L
P
K
A
K
S
H
A
P
E
V
I
T
Site 34
T483
S
H
A
P
E
V
I
T
S
S
P
L
K
_
_
Site 35
S484
H
A
P
E
V
I
T
S
S
P
L
K
_
_
_
Site 36
S485
A
P
E
V
I
T
S
S
P
L
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation