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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYB5R3
Full Name:
NADH-cytochrome b5 reductase 3
Alias:
B5R; Cytochrome b5 reductase; Cytochrome b5 reductase 3; DIA1; Diaphorase; Diaphorase (NADH) (cytochrome b-5 reductase); Diaphorase-1; EC 1.6.2.2; NB5R3; NCB5R
Type:
Membrane, Mitochondrial outer membrane, Hemoglobin complex, Cytoplasm, Mitochondrial inner membrane, Endoplasmic reticulum, Mitochondrion, Endoplasmic reticulum membrane protein
Mass (Da):
34235
Number AA:
301
UniProt ID:
P00387
International Prot ID:
IPI00328415
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005833
GO:0005741
Uniprot
OncoNet
Molecular Function:
GO:0004128
GO:0003924
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0008015
GO:0006695
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
M
K
L
F
Q
R
S
T
P
A
I
T
L
E
S
Site 2
S38
T
P
A
I
T
L
E
S
P
D
I
K
Y
P
L
Site 3
Y43
L
E
S
P
D
I
K
Y
P
L
R
L
I
D
R
Site 4
T57
R
E
I
I
S
H
D
T
R
R
F
R
F
A
L
Site 5
Y80
L
P
V
G
Q
H
I
Y
L
S
A
R
I
D
G
Site 6
S82
V
G
Q
H
I
Y
L
S
A
R
I
D
G
N
L
Site 7
Y94
G
N
L
V
V
R
P
Y
T
P
I
S
S
D
D
Site 8
T95
N
L
V
V
R
P
Y
T
P
I
S
S
D
D
D
Site 9
S98
V
R
P
Y
T
P
I
S
S
D
D
D
K
G
F
Site 10
S99
R
P
Y
T
P
I
S
S
D
D
D
K
G
F
V
Site 11
Y113
V
D
L
V
I
K
V
Y
F
K
D
T
H
P
K
Site 12
T117
I
K
V
Y
F
K
D
T
H
P
K
F
P
A
G
Site 13
S128
F
P
A
G
G
K
M
S
Q
Y
L
E
S
M
Q
Site 14
Y130
A
G
G
K
M
S
Q
Y
L
E
S
M
Q
I
G
Site 15
T139
E
S
M
Q
I
G
D
T
I
E
F
R
G
P
S
Site 16
Y151
G
P
S
G
L
L
V
Y
Q
G
K
G
K
F
A
Site 17
S165
A
I
R
P
D
K
K
S
N
P
I
I
R
T
V
Site 18
T202
M
K
D
P
D
D
H
T
V
C
H
L
L
F
A
Site 19
S230
E
E
L
R
N
K
H
S
A
R
F
K
L
W
Y
Site 20
Y237
S
A
R
F
K
L
W
Y
T
L
D
R
A
P
E
Site 21
T238
A
R
F
K
L
W
Y
T
L
D
R
A
P
E
A
Site 22
Y248
R
A
P
E
A
W
D
Y
G
Q
G
F
V
N
E
Site 23
Y282
G
P
P
P
M
I
Q
Y
A
C
L
P
N
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation