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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLPTM1
Full Name:
Cleft lip and palate transmembrane protein 1
Alias:
cleft lip and palate associated transmembrane protein 1; cleft lip and palate transmembrane 1; CLPT1
Type:
Mass (Da):
76097
Number AA:
669
UniProt ID:
O96005
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009897
GO:0005887
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0033081
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
V
A
A
G
G
G
S
S
G
Q
V
T
S
N
G
Site 2
T26
G
G
S
S
G
Q
V
T
S
N
G
S
I
G
R
Site 3
S27
G
S
S
G
Q
V
T
S
N
G
S
I
G
R
D
Site 4
S30
G
Q
V
T
S
N
G
S
I
G
R
D
P
P
A
Site 5
S93
G
G
A
P
R
V
A
S
R
N
L
F
P
K
D
Site 6
T101
R
N
L
F
P
K
D
T
L
M
N
L
H
V
Y
Site 7
Y108
T
L
M
N
L
H
V
Y
I
S
E
H
E
H
F
Site 8
Y133
W
E
Q
H
D
L
V
Y
G
D
W
T
S
G
E
Site 9
S138
L
V
Y
G
D
W
T
S
G
E
N
S
D
G
C
Site 10
Y146
G
E
N
S
D
G
C
Y
E
H
F
A
E
L
D
Site 11
S157
A
E
L
D
I
P
Q
S
V
Q
Q
N
G
S
I
Site 12
Y165
V
Q
Q
N
G
S
I
Y
I
H
V
Y
F
T
K
Site 13
Y185
D
P
R
Q
K
A
L
Y
R
R
L
A
T
V
H
Site 14
Y200
M
S
R
M
I
N
K
Y
K
R
R
R
F
Q
K
Site 15
T208
K
R
R
R
F
Q
K
T
K
N
L
L
T
G
E
Site 16
T213
Q
K
T
K
N
L
L
T
G
E
T
E
A
D
P
Site 17
T216
K
N
L
L
T
G
E
T
E
A
D
P
E
M
I
Site 18
Y229
M
I
K
R
A
E
D
Y
G
P
V
E
V
I
S
Site 19
T251
I
N
I
V
D
D
H
T
P
W
V
K
G
S
V
Site 20
S257
H
T
P
W
V
K
G
S
V
P
P
P
L
D
Q
Site 21
Y265
V
P
P
P
L
D
Q
Y
V
K
F
D
A
V
S
Site 22
Y275
F
D
A
V
S
G
D
Y
Y
P
I
I
Y
F
N
Site 23
Y276
D
A
V
S
G
D
Y
Y
P
I
I
Y
F
N
D
Site 24
Y280
G
D
Y
Y
P
I
I
Y
F
N
D
Y
W
N
L
Site 25
Y284
P
I
I
Y
F
N
D
Y
W
N
L
Q
K
D
Y
Site 26
Y291
Y
W
N
L
Q
K
D
Y
Y
P
I
N
E
S
L
Site 27
Y292
W
N
L
Q
K
D
Y
Y
P
I
N
E
S
L
A
Site 28
S297
D
Y
Y
P
I
N
E
S
L
A
S
L
P
L
R
Site 29
Y318
S
L
W
R
W
Q
L
Y
A
A
Q
S
T
K
S
Site 30
S325
Y
A
A
Q
S
T
K
S
P
W
N
F
L
G
D
Site 31
Y335
N
F
L
G
D
E
L
Y
E
Q
S
D
E
E
Q
Site 32
S338
G
D
E
L
Y
E
Q
S
D
E
E
Q
D
S
V
Site 33
S344
Q
S
D
E
E
Q
D
S
V
K
V
A
L
L
E
Site 34
S387
Q
F
W
N
S
R
Q
S
L
E
G
L
S
V
R
Site 35
S392
R
Q
S
L
E
G
L
S
V
R
S
V
F
F
G
Site 36
S456
A
G
I
F
P
R
L
S
F
K
D
K
S
T
Y
Site 37
S461
R
L
S
F
K
D
K
S
T
Y
I
E
S
S
T
Site 38
T462
L
S
F
K
D
K
S
T
Y
I
E
S
S
T
K
Site 39
Y463
S
F
K
D
K
S
T
Y
I
E
S
S
T
K
V
Site 40
Y471
I
E
S
S
T
K
V
Y
D
D
M
A
F
R
Y
Site 41
Y497
Y
A
V
Y
S
L
L
Y
L
E
H
K
G
W
Y
Site 42
T545
H
L
P
W
R
M
L
T
Y
K
A
L
N
T
F
Site 43
Y588
Y
L
Y
Q
R
W
I
Y
R
V
D
P
T
R
V
Site 44
S601
R
V
N
E
F
G
M
S
G
E
D
P
T
A
A
Site 45
T606
G
M
S
G
E
D
P
T
A
A
A
P
V
A
E
Site 46
T639
A
T
R
E
E
A
S
T
S
L
P
T
K
P
T
Site 47
S640
T
R
E
E
A
S
T
S
L
P
T
K
P
T
Q
Site 48
T646
T
S
L
P
T
K
P
T
Q
G
A
S
S
A
S
Site 49
S650
T
K
P
T
Q
G
A
S
S
A
S
E
P
Q
E
Site 50
S651
K
P
T
Q
G
A
S
S
A
S
E
P
Q
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation