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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBX6
Full Name:
T-box transcription factor TBX6
Alias:
Type:
Mass (Da):
47045
Number AA:
436
UniProt ID:
O95947
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
Y
H
P
R
E
L
Y
P
S
L
G
A
G
Y
Site 2
S10
H
P
R
E
L
Y
P
S
L
G
A
G
Y
R
L
Site 3
S26
P
A
Q
P
G
A
D
S
S
F
P
P
A
L
A
Site 4
S27
A
Q
P
G
A
D
S
S
F
P
P
A
L
A
E
Site 5
Y36
P
P
A
L
A
E
G
Y
R
Y
P
E
L
D
T
Site 6
Y38
A
L
A
E
G
Y
R
Y
P
E
L
D
T
P
K
Site 7
T43
Y
R
Y
P
E
L
D
T
P
K
L
D
C
F
L
Site 8
S51
P
K
L
D
C
F
L
S
G
M
E
A
A
P
R
Site 9
T59
G
M
E
A
A
P
R
T
L
A
A
H
P
P
L
Site 10
S80
M
G
T
E
P
A
P
S
A
P
E
A
L
H
S
Site 11
S92
L
H
S
L
P
G
V
S
L
S
L
E
N
R
E
Site 12
S94
S
L
P
G
V
S
L
S
L
E
N
R
E
L
W
Site 13
S105
R
E
L
W
K
E
F
S
S
V
G
T
E
M
I
Site 14
S161
Q
G
R
R
W
E
P
S
G
K
A
E
P
R
L
Site 15
Y173
P
R
L
P
D
R
V
Y
I
H
P
D
S
P
A
Site 16
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Site 17
T198
S
F
H
R
V
K
L
T
N
S
T
L
D
P
H
Site 18
T201
R
V
K
L
T
N
S
T
L
D
P
H
G
H
L
Site 19
Y216
I
L
H
S
M
H
K
Y
Q
P
R
I
H
L
V
Site 20
S248
F
P
E
T
T
F
I
S
V
T
A
Y
Q
N
P
Site 21
Y252
T
F
I
S
V
T
A
Y
Q
N
P
Q
I
T
Q
Site 22
T298
R
G
P
E
P
A
A
T
E
A
Y
G
S
G
D
Site 23
S303
A
A
T
E
A
Y
G
S
G
D
T
P
G
G
P
Site 24
T306
E
A
Y
G
S
G
D
T
P
G
G
P
C
D
S
Site 25
S313
T
P
G
G
P
C
D
S
T
L
G
G
D
I
R
Site 26
T314
P
G
G
P
C
D
S
T
L
G
G
D
I
R
E
Site 27
S322
L
G
G
D
I
R
E
S
D
P
E
Q
A
P
A
Site 28
S361
A
A
F
H
G
A
P
S
H
L
P
T
R
S
P
Site 29
T365
G
A
P
S
H
L
P
T
R
S
P
S
F
P
E
Site 30
S367
P
S
H
L
P
T
R
S
P
S
F
P
E
A
P
Site 31
S369
H
L
P
T
R
S
P
S
F
P
E
A
P
D
S
Site 32
S376
S
F
P
E
A
P
D
S
G
R
S
A
P
Y
S
Site 33
S379
E
A
P
D
S
G
R
S
A
P
Y
S
A
A
F
Site 34
S383
S
G
R
S
A
P
Y
S
A
A
F
L
E
L
P
Site 35
Y398
H
G
S
G
G
S
G
Y
P
A
A
P
P
A
V
Site 36
T422
G
P
F
P
L
P
Y
T
A
P
G
G
Y
L
D
Site 37
Y427
P
Y
T
A
P
G
G
Y
L
D
V
G
S
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation