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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBX18
Full Name:
T-box transcription factor TBX18
Alias:
Type:
Mass (Da):
64753
Number AA:
607
UniProt ID:
O95935
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
E
K
R
R
G
S
P
C
S
M
L
S
L
Site 2
S11
K
R
R
G
S
P
C
S
M
L
S
L
K
A
H
Site 3
S67
G
A
G
E
K
G
S
S
E
G
D
E
G
A
A
Site 4
S83
P
P
P
A
G
A
T
S
G
P
A
R
S
G
A
Site 5
S109
D
G
F
Q
Q
G
A
S
P
L
A
S
P
G
G
Site 6
S113
Q
G
A
S
P
L
A
S
P
G
G
S
P
K
G
Site 7
S117
P
L
A
S
P
G
G
S
P
K
G
S
P
A
R
Site 8
S121
P
G
G
S
P
K
G
S
P
A
R
S
L
A
R
Site 9
S125
P
K
G
S
P
A
R
S
L
A
R
P
G
T
P
Site 10
T131
R
S
L
A
R
P
G
T
P
L
P
S
P
Q
A
Site 11
S135
R
P
G
T
P
L
P
S
P
Q
A
P
R
V
D
Site 12
Y185
G
L
D
P
H
Q
Q
Y
Y
I
A
M
D
I
V
Site 13
Y199
V
P
V
D
N
K
R
Y
R
Y
V
Y
H
S
S
Site 14
Y201
V
D
N
K
R
Y
R
Y
V
Y
H
S
S
K
W
Site 15
Y203
N
K
R
Y
R
Y
V
Y
H
S
S
K
W
M
V
Site 16
S216
M
V
A
G
N
A
D
S
P
V
P
P
R
V
Y
Site 17
Y223
S
P
V
P
P
R
V
Y
I
H
P
D
S
P
A
Site 18
S228
R
V
Y
I
H
P
D
S
P
A
S
G
E
T
W
Site 19
S231
I
H
P
D
S
P
A
S
G
E
T
W
M
R
Q
Site 20
S241
T
W
M
R
Q
V
I
S
F
D
K
L
K
L
T
Site 21
T248
S
F
D
K
L
K
L
T
N
N
E
L
D
D
Q
Site 22
Y266
I
L
H
S
M
H
K
Y
Q
P
R
V
H
V
I
Site 23
S282
K
D
C
G
D
D
L
S
P
I
K
P
V
P
S
Site 24
T304
S
F
P
E
T
V
F
T
T
V
T
A
Y
Q
N
Site 25
T315
A
Y
Q
N
Q
Q
I
T
R
L
K
I
D
R
N
Site 26
S331
F
A
K
G
F
R
D
S
G
R
N
R
M
G
L
Site 27
S351
S
Y
A
F
W
R
P
S
L
R
T
L
T
F
E
Site 28
T354
F
W
R
P
S
L
R
T
L
T
F
E
D
I
P
Site 29
T356
R
P
S
L
R
T
L
T
F
E
D
I
P
G
I
Site 30
S370
I
P
K
Q
G
N
A
S
S
S
T
L
L
Q
G
Site 31
S372
K
Q
G
N
A
S
S
S
T
L
L
Q
G
T
G
Site 32
T385
T
G
N
G
V
P
A
T
H
P
H
L
L
S
G
Site 33
S391
A
T
H
P
H
L
L
S
G
S
S
C
S
S
P
Site 34
S393
H
P
H
L
L
S
G
S
S
C
S
S
P
A
F
Site 35
S394
P
H
L
L
S
G
S
S
C
S
S
P
A
F
H
Site 36
S397
L
S
G
S
S
C
S
S
P
A
F
H
L
G
P
Site 37
S411
P
N
T
S
Q
L
C
S
L
A
P
A
D
Y
S
Site 38
Y417
C
S
L
A
P
A
D
Y
S
A
C
A
R
S
G
Site 39
T426
A
C
A
R
S
G
L
T
L
N
R
Y
S
T
S
Site 40
Y430
S
G
L
T
L
N
R
Y
S
T
S
L
A
E
T
Site 41
S431
G
L
T
L
N
R
Y
S
T
S
L
A
E
T
Y
Site 42
T432
L
T
L
N
R
Y
S
T
S
L
A
E
T
Y
N
Site 43
S433
T
L
N
R
Y
S
T
S
L
A
E
T
Y
N
R
Site 44
T437
Y
S
T
S
L
A
E
T
Y
N
R
L
T
N
Q
Site 45
Y438
S
T
S
L
A
E
T
Y
N
R
L
T
N
Q
A
Site 46
T442
A
E
T
Y
N
R
L
T
N
Q
A
G
E
T
F
Site 47
T448
L
T
N
Q
A
G
E
T
F
A
P
P
R
T
P
Site 48
T454
E
T
F
A
P
P
R
T
P
S
Y
V
G
V
S
Site 49
S456
F
A
P
P
R
T
P
S
Y
V
G
V
S
S
S
Site 50
Y457
A
P
P
R
T
P
S
Y
V
G
V
S
S
S
T
Site 51
S461
T
P
S
Y
V
G
V
S
S
S
T
S
V
N
M
Site 52
S462
P
S
Y
V
G
V
S
S
S
T
S
V
N
M
S
Site 53
S469
S
S
T
S
V
N
M
S
M
G
G
T
D
G
D
Site 54
T473
V
N
M
S
M
G
G
T
D
G
D
T
F
S
C
Site 55
T477
M
G
G
T
D
G
D
T
F
S
C
P
Q
T
S
Site 56
S479
G
T
D
G
D
T
F
S
C
P
Q
T
S
L
S
Site 57
T483
D
T
F
S
C
P
Q
T
S
L
S
M
Q
I
S
Site 58
S484
T
F
S
C
P
Q
T
S
L
S
M
Q
I
S
G
Site 59
S486
S
C
P
Q
T
S
L
S
M
Q
I
S
G
M
S
Site 60
S490
T
S
L
S
M
Q
I
S
G
M
S
P
Q
L
Q
Site 61
S493
S
M
Q
I
S
G
M
S
P
Q
L
Q
Y
I
M
Site 62
Y498
G
M
S
P
Q
L
Q
Y
I
M
P
S
P
S
S
Site 63
S502
Q
L
Q
Y
I
M
P
S
P
S
S
N
A
F
A
Site 64
S504
Q
Y
I
M
P
S
P
S
S
N
A
F
A
T
N
Site 65
S505
Y
I
M
P
S
P
S
S
N
A
F
A
T
N
Q
Site 66
T520
T
H
Q
G
S
Y
N
T
F
R
L
H
S
P
C
Site 67
Y530
L
H
S
P
C
A
L
Y
G
Y
N
F
S
T
S
Site 68
Y532
S
P
C
A
L
Y
G
Y
N
F
S
T
S
P
K
Site 69
S535
A
L
Y
G
Y
N
F
S
T
S
P
K
L
A
A
Site 70
S537
Y
G
Y
N
F
S
T
S
P
K
L
A
A
S
P
Site 71
S543
T
S
P
K
L
A
A
S
P
E
K
I
V
S
S
Site 72
S549
A
S
P
E
K
I
V
S
S
Q
G
S
F
L
G
Site 73
S550
S
P
E
K
I
V
S
S
Q
G
S
F
L
G
S
Site 74
S553
K
I
V
S
S
Q
G
S
F
L
G
S
S
P
S
Site 75
S557
S
Q
G
S
F
L
G
S
S
P
S
G
T
M
T
Site 76
S558
Q
G
S
F
L
G
S
S
P
S
G
T
M
T
D
Site 77
S560
S
F
L
G
S
S
P
S
G
T
M
T
D
R
Q
Site 78
T562
L
G
S
S
P
S
G
T
M
T
D
R
Q
M
L
Site 79
T564
S
S
P
S
G
T
M
T
D
R
Q
M
L
P
P
Site 80
S579
V
E
G
V
H
L
L
S
S
G
G
Q
Q
S
F
Site 81
S580
E
G
V
H
L
L
S
S
G
G
Q
Q
S
F
F
Site 82
S585
L
S
S
G
G
Q
Q
S
F
F
D
S
R
T
L
Site 83
S589
G
Q
Q
S
F
F
D
S
R
T
L
G
S
L
T
Site 84
T591
Q
S
F
F
D
S
R
T
L
G
S
L
T
L
S
Site 85
S594
F
D
S
R
T
L
G
S
L
T
L
S
S
S
Q
Site 86
T596
S
R
T
L
G
S
L
T
L
S
S
S
Q
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation