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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC4
Full Name:
Tetratricopeptide repeat protein 4
Alias:
FLJ41930; MGC5097; Tetratricopeptide repeat domain 4
Type:
Unknown function
Mass (Da):
44679
Number AA:
387
UniProt ID:
O95801
International Prot ID:
IPI00000606
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
Q
P
G
Q
D
P
T
S
D
D
V
M
D
S
F
Site 2
S16
T
S
D
D
V
M
D
S
F
L
E
K
F
Q
S
Site 3
S23
S
F
L
E
K
F
Q
S
Q
P
Y
R
G
G
F
Site 4
S47
E
K
V
P
L
F
M
S
R
A
P
S
E
I
D
Site 5
S51
L
F
M
S
R
A
P
S
E
I
D
P
R
E
N
Site 6
S66
P
D
L
A
C
L
Q
S
I
I
F
D
E
E
R
Site 7
S74
I
I
F
D
E
E
R
S
P
E
E
Q
A
K
T
Site 8
T81
S
P
E
E
Q
A
K
T
Y
K
D
E
G
N
D
Site 9
Y89
Y
K
D
E
G
N
D
Y
F
K
E
K
D
Y
K
Site 10
Y95
D
Y
F
K
E
K
D
Y
K
K
A
V
I
S
Y
Site 11
Y120
P
D
L
N
A
V
L
Y
T
N
R
A
A
A
Q
Site 12
Y128
T
N
R
A
A
A
Q
Y
Y
L
G
N
F
R
S
Site 13
Y129
N
R
A
A
A
Q
Y
Y
L
G
N
F
R
S
A
Site 14
S135
Y
Y
L
G
N
F
R
S
A
L
N
D
V
T
A
Site 15
T141
R
S
A
L
N
D
V
T
A
A
R
K
L
K
P
Site 16
S234
K
A
R
N
I
R
L
S
E
A
A
C
E
D
E
Site 17
S243
A
A
C
E
D
E
D
S
A
S
E
G
L
G
E
Site 18
S245
C
E
D
E
D
S
A
S
E
G
L
G
E
L
F
Site 19
S257
E
L
F
L
D
G
L
S
T
E
N
P
H
G
A
Site 20
T258
L
F
L
D
G
L
S
T
E
N
P
H
G
A
R
Site 21
S267
N
P
H
G
A
R
L
S
L
D
G
Q
G
R
L
Site 22
Y282
S
W
P
V
L
F
L
Y
P
E
Y
A
Q
S
D
Site 23
S292
Y
A
Q
S
D
F
I
S
A
F
H
E
D
S
R
Site 24
T311
L
M
V
M
F
G
E
T
P
S
W
D
L
E
Q
Site 25
Y320
S
W
D
L
E
Q
K
Y
C
P
D
N
L
E
V
Site 26
Y328
C
P
D
N
L
E
V
Y
F
E
D
E
D
R
A
Site 27
Y338
D
E
D
R
A
E
L
Y
R
V
P
A
K
S
T
Site 28
Y355
Q
V
L
Q
H
Q
R
Y
F
V
K
A
L
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation