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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAU1
Full Name:
Double-stranded RNA-binding protein Staufen homolog 1
Alias:
Double-stranded RNA-binding protein Staufen 1; Staufen, RNA binding protein, 1
Type:
RNA binding protein
Mass (Da):
63164
Number AA:
577
UniProt ID:
O95793
International Prot ID:
IPI00000001
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005783
GO:0005791
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003725
PhosphoSite+
KinaseNET
Biological Process:
GO:0006403
GO:0008298
GO:0033036
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
Q
V
Q
V
Q
N
P
S
A
A
L
S
G
S
Q
Site 2
S16
Q
N
P
S
A
A
L
S
G
S
Q
I
L
N
K
Site 3
S18
P
S
A
A
L
S
G
S
Q
I
L
N
K
N
Q
Site 4
S26
Q
I
L
N
K
N
Q
S
L
L
S
Q
P
L
M
Site 5
S29
N
K
N
Q
S
L
L
S
Q
P
L
M
S
I
P
Site 6
S37
Q
P
L
M
S
I
P
S
T
T
S
S
L
P
S
Site 7
T38
P
L
M
S
I
P
S
T
T
S
S
L
P
S
E
Site 8
S40
M
S
I
P
S
T
T
S
S
L
P
S
E
N
A
Site 9
S41
S
I
P
S
T
T
S
S
L
P
S
E
N
A
G
Site 10
S44
S
T
T
S
S
L
P
S
E
N
A
G
R
P
I
Site 11
S54
A
G
R
P
I
Q
N
S
A
L
P
S
A
S
I
Site 12
S58
I
Q
N
S
A
L
P
S
A
S
I
T
S
T
S
Site 13
S60
N
S
A
L
P
S
A
S
I
T
S
T
S
A
A
Site 14
Y90
K
L
G
K
K
P
M
Y
K
P
V
D
P
Y
S
Site 15
Y96
M
Y
K
P
V
D
P
Y
S
R
M
Q
S
T
Y
Site 16
Y103
Y
S
R
M
Q
S
T
Y
N
Y
N
M
R
G
G
Site 17
Y105
R
M
Q
S
T
Y
N
Y
N
M
R
G
G
A
Y
Site 18
Y112
Y
N
M
R
G
G
A
Y
P
P
R
Y
F
Y
P
Site 19
Y116
G
G
A
Y
P
P
R
Y
F
Y
P
F
P
V
P
Site 20
Y118
A
Y
P
P
R
Y
F
Y
P
F
P
V
P
P
L
Site 21
S176
L
E
V
N
G
R
E
S
E
E
E
N
L
N
K
Site 22
S208
N
F
E
V
A
R
E
S
G
P
P
H
M
K
N
Site 23
S221
K
N
F
V
T
K
V
S
V
G
E
F
V
G
E
Site 24
S233
V
G
E
G
E
G
K
S
K
K
I
S
K
K
N
Site 25
S237
E
G
K
S
K
K
I
S
K
K
N
A
A
I
A
Site 26
T269
K
P
R
I
K
K
K
T
K
P
I
V
K
P
Q
Site 27
S278
P
I
V
K
P
Q
T
S
P
E
Y
G
Q
G
I
Site 28
Y281
K
P
Q
T
S
P
E
Y
G
Q
G
I
N
P
I
Site 29
S289
G
Q
G
I
N
P
I
S
R
L
A
Q
I
Q
Q
Site 30
Y305
K
K
E
K
E
P
E
Y
T
L
L
T
E
R
G
Site 31
T306
K
E
K
E
P
E
Y
T
L
L
T
E
R
G
L
Site 32
T309
E
P
E
Y
T
L
L
T
E
R
G
L
P
R
R
Site 33
T335
H
T
A
E
G
T
G
T
N
K
K
V
A
K
R
Site 34
S368
P
T
K
P
A
L
K
S
E
E
K
T
P
I
K
Site 35
T372
A
L
K
S
E
E
K
T
P
I
K
K
P
G
D
Site 36
T384
P
G
D
G
R
K
V
T
F
F
E
P
G
S
G
Site 37
S390
V
T
F
F
E
P
G
S
G
D
E
N
G
T
S
Site 38
S397
S
G
D
E
N
G
T
S
N
K
E
D
E
F
R
Site 39
Y407
E
D
E
F
R
M
P
Y
L
S
H
Q
Q
L
P
Site 40
S409
E
F
R
M
P
Y
L
S
H
Q
Q
L
P
A
G
Site 41
Y461
M
I
A
R
E
L
L
Y
G
G
T
S
P
T
A
Site 42
S477
T
I
L
K
N
N
I
S
S
G
H
V
P
H
G
Site 43
T487
H
V
P
H
G
P
L
T
R
P
S
E
Q
L
D
Site 44
S490
H
G
P
L
T
R
P
S
E
Q
L
D
Y
L
S
Site 45
Y495
R
P
S
E
Q
L
D
Y
L
S
R
V
Q
G
F
Site 46
S497
S
E
Q
L
D
Y
L
S
R
V
Q
G
F
Q
V
Site 47
Y506
V
Q
G
F
Q
V
E
Y
K
D
F
P
K
N
N
Site 48
S519
N
N
K
N
E
F
V
S
L
I
N
C
S
S
Q
Site 49
S531
S
S
Q
P
P
L
I
S
H
G
I
G
K
D
V
Site 50
S554
L
N
I
L
K
L
L
S
E
L
D
Q
Q
S
T
Site 51
S560
L
S
E
L
D
Q
Q
S
T
E
M
P
R
T
G
Site 52
T561
S
E
L
D
Q
Q
S
T
E
M
P
R
T
G
N
Site 53
T566
Q
S
T
E
M
P
R
T
G
N
G
P
M
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation