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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLF8
Full Name:
Krueppel-like factor 8
Alias:
Basic krueppel-like factor 3; BKLF3; Zinc finger protein 741; ZNF741
Type:
Intracellular, Nucleus protein
Mass (Da):
39314
Number AA:
359
UniProt ID:
O95600
International Prot ID:
IPI00478866
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
Q
L
N
S
E
G
G
S
M
Q
V
F
K
Q
V
Site 2
S31
V
F
K
Q
V
T
A
S
V
R
N
R
D
P
P
Site 3
Y42
R
D
P
P
E
I
E
Y
R
S
N
M
T
S
P
Site 4
S44
P
P
E
I
E
Y
R
S
N
M
T
S
P
T
L
Site 5
S48
E
Y
R
S
N
M
T
S
P
T
L
L
D
A
N
Site 6
S77
P
P
E
E
L
L
A
S
D
F
S
L
P
Q
V
Site 7
S90
Q
V
E
P
V
D
L
S
F
H
K
P
K
A
P
Site 8
S102
K
A
P
L
Q
P
A
S
M
L
Q
A
P
I
R
Site 9
S115
I
R
P
P
K
P
Q
S
S
P
Q
T
L
V
V
Site 10
S116
R
P
P
K
P
Q
S
S
P
Q
T
L
V
V
S
Site 11
T119
K
P
Q
S
S
P
Q
T
L
V
V
S
T
S
T
Site 12
S123
S
P
Q
T
L
V
V
S
T
S
T
S
D
M
S
Site 13
S125
Q
T
L
V
V
S
T
S
T
S
D
M
S
T
S
Site 14
S127
L
V
V
S
T
S
T
S
D
M
S
T
S
A
N
Site 15
S130
S
T
S
T
S
D
M
S
T
S
A
N
I
P
T
Site 16
T131
T
S
T
S
D
M
S
T
S
A
N
I
P
T
V
Site 17
S132
S
T
S
D
M
S
T
S
A
N
I
P
T
V
L
Site 18
S143
P
T
V
L
T
P
G
S
V
L
T
S
S
Q
S
Site 19
T146
L
T
P
G
S
V
L
T
S
S
Q
S
T
G
S
Site 20
S147
T
P
G
S
V
L
T
S
S
Q
S
T
G
S
Q
Site 21
S148
P
G
S
V
L
T
S
S
Q
S
T
G
S
Q
Q
Site 22
S150
S
V
L
T
S
S
Q
S
T
G
S
Q
Q
I
L
Site 23
T151
V
L
T
S
S
Q
S
T
G
S
Q
Q
I
L
H
Site 24
S153
T
S
S
Q
S
T
G
S
Q
Q
I
L
H
V
I
Site 25
S167
I
H
T
I
P
S
V
S
L
P
N
K
M
G
G
Site 26
T190
Q
S
L
P
M
V
Y
T
T
L
P
A
D
G
G
Site 27
S215
G
D
G
K
N
A
G
S
V
K
V
D
P
T
S
Site 28
T221
G
S
V
K
V
D
P
T
S
M
S
P
L
E
I
Site 29
S222
S
V
K
V
D
P
T
S
M
S
P
L
E
I
P
Site 30
S224
K
V
D
P
T
S
M
S
P
L
E
I
P
S
D
Site 31
S230
M
S
P
L
E
I
P
S
D
S
E
E
S
T
I
Site 32
S232
P
L
E
I
P
S
D
S
E
E
S
T
I
E
S
Site 33
S235
I
P
S
D
S
E
E
S
T
I
E
S
G
S
S
Site 34
T236
P
S
D
S
E
E
S
T
I
E
S
G
S
S
A
Site 35
S239
S
E
E
S
T
I
E
S
G
S
S
A
L
Q
S
Site 36
S241
E
S
T
I
E
S
G
S
S
A
L
Q
S
L
Q
Site 37
S242
S
T
I
E
S
G
S
S
A
L
Q
S
L
Q
G
Site 38
S246
S
G
S
S
A
L
Q
S
L
Q
G
L
Q
Q
E
Site 39
T286
A
G
C
S
K
V
Y
T
K
S
S
H
L
K
A
Site 40
S288
C
S
K
V
Y
T
K
S
S
H
L
K
A
H
R
Site 41
S289
S
K
V
Y
T
K
S
S
H
L
K
A
H
R
R
Site 42
T299
K
A
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 43
T322
F
A
R
S
D
E
L
T
R
H
F
R
K
H
T
Site 44
T329
T
R
H
F
R
K
H
T
G
I
K
P
F
R
C
Site 45
S342
R
C
T
D
C
N
R
S
F
S
R
S
D
H
L
Site 46
S344
T
D
C
N
R
S
F
S
R
S
D
H
L
S
L
Site 47
S346
C
N
R
S
F
S
R
S
D
H
L
S
L
H
R
Site 48
S350
F
S
R
S
D
H
L
S
L
H
R
R
R
H
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation