KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LARGE
Full Name:
Glycosyltransferase-like protein LARGE1
Alias:
Acetylglucosaminyltransferase-like 1A
Type:
Mass (Da):
88066
Number AA:
756
UniProt ID:
O95461
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
W
I
Y
L
F
S
G
S
F
E
D
G
K
P
V
Site 2
S41
F
E
D
G
K
P
V
S
L
S
P
L
E
S
Q
Site 3
S43
D
G
K
P
V
S
L
S
P
L
E
S
Q
A
H
Site 4
S47
V
S
L
S
P
L
E
S
Q
A
H
S
P
R
Y
Site 5
S51
P
L
E
S
Q
A
H
S
P
R
Y
T
A
S
S
Site 6
Y54
S
Q
A
H
S
P
R
Y
T
A
S
S
Q
R
E
Site 7
T55
Q
A
H
S
P
R
Y
T
A
S
S
Q
R
E
R
Site 8
S57
H
S
P
R
Y
T
A
S
S
Q
R
E
R
E
S
Site 9
S58
S
P
R
Y
T
A
S
S
Q
R
E
R
E
S
L
Site 10
S64
S
S
Q
R
E
R
E
S
L
E
V
R
M
R
E
Site 11
S84
R
A
L
R
R
Q
L
S
L
A
Q
G
R
A
P
Site 12
S92
L
A
Q
G
R
A
P
S
H
R
R
G
N
H
S
Site 13
S99
S
H
R
R
G
N
H
S
K
T
Y
S
M
E
E
Site 14
T101
R
R
G
N
H
S
K
T
Y
S
M
E
E
G
T
Site 15
Y102
R
G
N
H
S
K
T
Y
S
M
E
E
G
T
G
Site 16
S103
G
N
H
S
K
T
Y
S
M
E
E
G
T
G
D
Site 17
S123
A
G
I
V
A
G
N
S
S
E
C
G
Q
Q
P
Site 18
S124
G
I
V
A
G
N
S
S
E
C
G
Q
Q
P
V
Site 19
Y199
P
A
V
R
V
D
F
Y
N
A
D
E
L
K
S
Site 20
S209
D
E
L
K
S
E
V
S
W
I
P
N
K
H
Y
Site 21
Y216
S
W
I
P
N
K
H
Y
S
G
I
Y
G
L
M
Site 22
S274
L
G
L
V
E
N
Q
S
D
W
Y
L
G
N
L
Site 23
Y277
V
E
N
Q
S
D
W
Y
L
G
N
L
W
K
N
Site 24
Y295
W
P
A
L
G
R
G
Y
N
T
G
V
I
L
L
Site 25
S329
R
E
L
M
G
M
L
S
T
S
L
A
D
Q
D
Site 26
Y350
K
Q
N
P
F
L
V
Y
Q
L
P
C
F
W
N
Site 27
Y370
H
T
R
S
E
Q
C
Y
R
D
V
S
D
L
K
Site 28
S383
L
K
V
I
H
W
N
S
P
K
K
L
R
V
K
Site 29
Y407
L
Y
L
T
F
L
E
Y
D
G
N
L
L
R
R
Site 30
S421
R
E
L
F
G
C
P
S
E
A
D
V
N
S
E
Site 31
S435
E
N
L
Q
K
Q
L
S
E
L
D
E
D
D
L
Site 32
Y444
L
D
E
D
D
L
C
Y
E
F
R
R
E
R
F
Site 33
T452
E
F
R
R
E
R
F
T
V
H
R
T
H
L
Y
Site 34
Y459
T
V
H
R
T
H
L
Y
F
L
H
Y
E
Y
E
Site 35
S471
E
Y
E
P
A
A
D
S
T
D
V
T
L
V
A
Site 36
S500
K
H
W
E
G
P
I
S
L
A
L
Y
L
S
D
Site 37
Y516
E
A
Q
Q
F
L
R
Y
A
Q
G
S
E
V
L
Site 38
S520
F
L
R
Y
A
Q
G
S
E
V
L
M
S
R
H
Site 39
S525
Q
G
S
E
V
L
M
S
R
H
N
V
G
Y
H
Site 40
Y531
M
S
R
H
N
V
G
Y
H
I
V
Y
K
E
G
Site 41
Y535
N
V
G
Y
H
I
V
Y
K
E
G
Q
F
Y
P
Site 42
Y541
V
Y
K
E
G
Q
F
Y
P
V
N
L
L
R
N
Site 43
Y558
M
K
H
I
S
T
P
Y
M
F
L
S
D
I
D
Site 44
Y570
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Site 45
Y573
F
L
P
M
Y
G
L
Y
E
Y
L
R
K
S
V
Site 46
Y575
P
M
Y
G
L
Y
E
Y
L
R
K
S
V
I
Q
Site 47
T588
I
Q
L
D
L
A
N
T
K
K
A
M
I
V
P
Site 48
T599
M
I
V
P
A
F
E
T
L
R
Y
R
L
S
F
Site 49
Y602
P
A
F
E
T
L
R
Y
R
L
S
F
P
K
S
Site 50
S605
E
T
L
R
Y
R
L
S
F
P
K
S
K
A
E
Site 51
S609
Y
R
L
S
F
P
K
S
K
A
E
L
L
S
M
Site 52
T646
F
A
K
W
R
T
A
T
T
P
Y
R
V
E
W
Site 53
T647
A
K
W
R
T
A
T
T
P
Y
R
V
E
W
E
Site 54
Y660
W
E
A
D
F
E
P
Y
V
V
V
R
R
D
C
Site 55
Y670
V
R
R
D
C
P
E
Y
D
R
R
F
V
G
F
Site 56
T715
H
A
P
S
F
D
I
T
K
F
R
S
N
K
Q
Site 57
Y723
K
F
R
S
N
K
Q
Y
R
I
C
L
K
T
L
Site 58
T729
Q
Y
R
I
C
L
K
T
L
K
E
E
F
Q
Q
Site 59
S739
E
E
F
Q
Q
D
M
S
R
R
Y
G
F
A
A
Site 60
Y742
Q
Q
D
M
S
R
R
Y
G
F
A
A
L
K
Y
Site 61
Y749
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation