KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZBTB7A
Full Name:
Zinc finger and BTB domain-containing protein 7A
Alias:
FBI1; Leukemia/lymphoma-related factor; TIP21
Type:
Transcription protein
Mass (Da):
61439
Number AA:
584
UniProt ID:
O95365
International Prot ID:
IPI00026317
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0035035
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
G
I
P
F
P
D
H
S
S
D
I
L
S
G
L
Site 2
S18
I
P
F
P
D
H
S
S
D
I
L
S
G
L
N
Site 3
S22
D
H
S
S
D
I
L
S
G
L
N
E
Q
R
T
Site 4
T29
S
G
L
N
E
Q
R
T
Q
G
L
L
C
D
V
Site 5
T47
V
E
G
R
E
F
P
T
H
R
S
V
L
A
A
Site 6
S65
Y
F
K
K
L
F
T
S
G
A
V
V
D
Q
Q
Site 7
Y160
N
L
L
R
A
K
E
Y
L
E
F
F
Q
S
N
Site 8
S166
E
Y
L
E
F
F
Q
S
N
P
M
N
S
L
P
Site 9
S171
F
Q
S
N
P
M
N
S
L
P
P
A
A
A
A
Site 10
S186
A
A
A
S
F
P
W
S
A
F
G
A
S
D
D
Site 11
T198
S
D
D
D
L
D
A
T
K
E
A
V
A
A
A
Site 12
Y220
D
C
N
G
L
D
F
Y
G
P
G
P
P
A
E
Site 13
T231
P
P
A
E
R
P
P
T
G
D
G
D
E
G
D
Site 14
S239
G
D
G
D
E
G
D
S
N
P
G
L
W
P
E
Site 15
T253
E
R
D
E
D
A
P
T
G
G
L
F
P
P
P
Site 16
Y272
A
A
T
Q
N
G
H
Y
G
R
G
G
E
E
E
Site 17
S282
G
G
E
E
E
A
A
S
L
S
E
A
A
P
E
Site 18
S284
E
E
E
A
A
S
L
S
E
A
A
P
E
P
G
Site 19
S293
A
A
P
E
P
G
D
S
P
G
F
L
S
G
A
Site 20
S298
G
D
S
P
G
F
L
S
G
A
A
E
G
E
D
Site 21
S337
A
G
A
A
A
G
D
S
D
E
E
S
R
A
D
Site 22
S341
A
G
D
S
D
E
E
S
R
A
D
D
K
G
V
Site 23
Y351
D
D
K
G
V
M
D
Y
Y
L
K
Y
F
S
G
Site 24
Y352
D
K
G
V
M
D
Y
Y
L
K
Y
F
S
G
A
Site 25
Y355
V
M
D
Y
Y
L
K
Y
F
S
G
A
H
D
G
Site 26
Y365
G
A
H
D
G
D
V
Y
P
A
W
S
Q
K
V
Site 27
S369
G
D
V
Y
P
A
W
S
Q
K
V
E
K
K
I
Site 28
T403
K
L
P
R
H
I
R
T
H
T
G
E
K
P
Y
Site 29
T405
P
R
H
I
R
T
H
T
G
E
K
P
Y
E
C
Site 30
T420
N
I
C
K
V
R
F
T
R
Q
D
K
L
K
V
Site 31
T433
K
V
H
M
R
K
H
T
G
E
K
P
Y
L
C
Site 32
Y438
K
H
T
G
E
K
P
Y
L
C
Q
Q
C
G
A
Site 33
Y451
G
A
A
F
A
H
N
Y
D
L
K
N
H
M
R
Site 34
T461
K
N
H
M
R
V
H
T
G
L
R
P
Y
Q
C
Site 35
Y466
V
H
T
G
L
R
P
Y
Q
C
D
S
C
C
K
Site 36
S495
D
G
C
N
G
V
P
S
R
R
G
R
K
P
R
Site 37
S511
R
G
G
A
P
D
P
S
P
G
A
T
A
T
P
Site 38
T515
P
D
P
S
P
G
A
T
A
T
P
G
A
P
A
Site 39
T517
P
S
P
G
A
T
A
T
P
G
A
P
A
Q
P
Site 40
S525
P
G
A
P
A
Q
P
S
S
P
D
A
R
R
N
Site 41
S526
G
A
P
A
Q
P
S
S
P
D
A
R
R
N
G
Site 42
S549
D
E
D
E
D
V
A
S
P
D
G
L
G
R
L
Site 43
S567
G
A
G
G
G
G
D
S
G
G
G
P
G
A
A
Site 44
T575
G
G
G
P
G
A
A
T
D
G
N
F
T
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation