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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM16
Full Name:
Tripartite motif-containing protein 16
Alias:
EBBP; Estrogen-responsive B box; Estrogen-responsive B box protein; TM16; TRI16; Tripartite motif 16; Tripartite motif-containing 16
Type:
DNA binding protein, DNA repair
Mass (Da):
63955
Number AA:
564
UniProt ID:
O95361
International Prot ID:
IPI00007955
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016605
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0032089
GO:0019966
PhosphoSite+
KinaseNET
Biological Process:
GO:0043966
GO:0043967
GO:0043193
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
P
G
P
L
P
R
A
T
A
Q
P
P
A
P
L
Site 2
S24
A
Q
P
P
A
P
L
S
P
D
S
G
S
P
S
Site 3
S27
P
A
P
L
S
P
D
S
G
S
P
S
P
D
S
Site 4
S29
P
L
S
P
D
S
G
S
P
S
P
D
S
G
S
Site 5
S31
S
P
D
S
G
S
P
S
P
D
S
G
S
A
S
Site 6
S34
S
G
S
P
S
P
D
S
G
S
A
S
P
V
E
Site 7
S36
S
P
S
P
D
S
G
S
A
S
P
V
E
E
E
Site 8
S38
S
P
D
S
G
S
A
S
P
V
E
E
E
D
V
Site 9
S47
V
E
E
E
D
V
G
S
S
E
K
L
G
R
E
Site 10
T55
S
E
K
L
G
R
E
T
E
E
Q
D
S
D
S
Site 11
S60
R
E
T
E
E
Q
D
S
D
S
A
E
Q
G
D
Site 12
S62
T
E
E
Q
D
S
D
S
A
E
Q
G
D
P
A
Site 13
T120
K
L
Q
S
H
L
L
T
E
P
V
K
D
H
N
Site 14
S139
P
A
H
H
S
P
L
S
A
F
C
C
P
D
Q
Site 15
S164
H
S
G
H
T
I
V
S
L
D
A
A
R
R
D
Site 16
T179
K
E
A
E
L
Q
C
T
Q
L
D
L
E
R
K
Site 17
S203
R
L
Q
A
N
Q
K
S
V
L
V
S
V
S
E
Site 18
S246
E
K
E
Q
A
A
L
S
Q
A
N
G
I
K
A
Site 19
S265
R
S
A
E
M
E
K
S
K
Q
E
L
E
R
M
Site 20
T295
F
K
N
T
E
D
I
T
F
P
S
V
Y
V
G
Site 21
S298
T
E
D
I
T
F
P
S
V
Y
V
G
L
K
D
Site 22
Y341
E
F
S
K
E
E
E
Y
D
I
R
T
Q
V
S
Site 23
Y355
S
A
V
V
Q
R
K
Y
W
T
S
K
P
E
P
Site 24
T357
V
V
Q
R
K
Y
W
T
S
K
P
E
P
S
T
Site 25
S358
V
Q
R
K
Y
W
T
S
K
P
E
P
S
T
R
Site 26
S363
W
T
S
K
P
E
P
S
T
R
E
Q
F
L
Q
Site 27
T364
T
S
K
P
E
P
S
T
R
E
Q
F
L
Q
Y
Site 28
Y371
T
R
E
Q
F
L
Q
Y
A
Y
D
I
T
F
D
Site 29
T381
D
I
T
F
D
P
D
T
A
H
K
Y
L
R
L
Site 30
Y385
D
P
D
T
A
H
K
Y
L
R
L
Q
E
E
N
Site 31
T396
Q
E
E
N
R
K
V
T
N
T
T
P
W
E
H
Site 32
T398
E
N
R
K
V
T
N
T
T
P
W
E
H
P
Y
Site 33
T399
N
R
K
V
T
N
T
T
P
W
E
H
P
Y
P
Site 34
Y405
T
T
P
W
E
H
P
Y
P
D
L
P
S
R
F
Site 35
S420
L
H
W
R
Q
V
L
S
Q
Q
S
L
Y
L
H
Site 36
S423
R
Q
V
L
S
Q
Q
S
L
Y
L
H
R
Y
Y
Site 37
Y425
V
L
S
Q
Q
S
L
Y
L
H
R
Y
Y
F
E
Site 38
Y429
Q
S
L
Y
L
H
R
Y
Y
F
E
V
E
I
F
Site 39
Y430
S
L
Y
L
H
R
Y
Y
F
E
V
E
I
F
G
Site 40
Y441
E
I
F
G
A
G
T
Y
V
G
L
T
C
K
G
Site 41
T445
A
G
T
Y
V
G
L
T
C
K
G
I
D
R
K
Site 42
S458
R
K
G
E
E
R
N
S
C
I
S
G
N
N
F
Site 43
S461
E
E
R
N
S
C
I
S
G
N
N
F
S
W
S
Site 44
S481
K
E
F
T
A
W
Y
S
D
M
E
T
P
L
K
Site 45
T485
A
W
Y
S
D
M
E
T
P
L
K
A
G
P
F
Site 46
Y531
C
K
F
S
E
P
V
Y
A
A
F
W
L
S
K
Site 47
S537
V
Y
A
A
F
W
L
S
K
K
E
N
A
I
R
Site 48
S558
E
P
E
K
P
A
P
S
L
V
G
T
A
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation