KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RASAL1
Full Name:
RasGAP-activating-like protein 1
Alias:
GAP1 like; RAS protein activator like 1; RAS protein activator like 1 (GAP1 like); RASAL; RASL1
Type:
GTPase activating protein, Ras
Mass (Da):
89997
Number AA:
804
UniProt ID:
O95294
International Prot ID:
IPI00291306
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005099
GO:0005543
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
GO:0051056
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
K
S
S
S
L
N
V
R
V
V
E
Site 2
S23
A
L
P
A
K
D
V
S
G
S
S
D
P
Y
C
Site 3
S25
P
A
K
D
V
S
G
S
S
D
P
Y
C
L
V
Site 4
S26
A
K
D
V
S
G
S
S
D
P
Y
C
L
V
K
Site 5
Y29
V
S
G
S
S
D
P
Y
C
L
V
K
V
D
D
Site 6
T44
E
V
V
A
R
T
A
T
V
W
R
S
L
G
P
Site 7
S48
R
T
A
T
V
W
R
S
L
G
P
F
W
G
E
Site 8
Y57
G
P
F
W
G
E
E
Y
T
V
H
L
P
L
D
Site 9
T58
P
F
W
G
E
E
Y
T
V
H
L
P
L
D
F
Site 10
S88
D
D
I
I
G
K
I
S
L
S
R
E
A
I
T
Site 11
T95
S
L
S
R
E
A
I
T
A
D
P
R
G
I
D
Site 12
S103
A
D
P
R
G
I
D
S
W
I
N
L
S
R
V
Site 13
S108
I
D
S
W
I
N
L
S
R
V
D
P
D
A
E
Site 14
S151
D
L
A
P
R
D
I
S
G
T
S
D
P
F
A
Site 15
T153
A
P
R
D
I
S
G
T
S
D
P
F
A
R
V
Site 16
S164
F
A
R
V
F
W
G
S
Q
S
L
E
T
S
T
Site 17
S166
R
V
F
W
G
S
Q
S
L
E
T
S
T
I
K
Site 18
S170
G
S
Q
S
L
E
T
S
T
I
K
K
T
R
F
Site 19
S194
R
E
M
P
G
A
P
S
P
L
R
V
E
L
W
Site 20
S218
F
L
G
M
V
E
F
S
P
K
T
L
Q
Q
K
Site 21
T221
M
V
E
F
S
P
K
T
L
Q
Q
K
P
P
K
Site 22
S243
F
P
R
A
E
E
D
S
G
G
N
L
G
A
L
Site 23
S264
I
E
D
R
V
L
P
S
Q
C
Y
Q
P
L
M
Site 24
T286
Q
G
P
A
E
E
D
T
A
S
P
L
A
L
L
Site 25
S288
P
A
E
E
D
T
A
S
P
L
A
L
L
E
E
Site 26
T297
L
A
L
L
E
E
L
T
L
G
D
C
R
Q
D
Site 27
Y325
L
A
G
H
F
L
D
Y
L
T
R
R
E
V
A
Site 28
T327
G
H
F
L
D
Y
L
T
R
R
E
V
A
R
T
Site 29
T334
T
R
R
E
V
A
R
T
M
D
P
N
T
L
F
Site 30
T339
A
R
T
M
D
P
N
T
L
F
R
S
N
S
L
Site 31
S343
D
P
N
T
L
F
R
S
N
S
L
A
S
K
S
Site 32
S345
N
T
L
F
R
S
N
S
L
A
S
K
S
M
E
Site 33
S350
S
N
S
L
A
S
K
S
M
E
Q
F
M
K
L
Site 34
Y380
R
V
F
E
E
K
K
Y
M
E
L
D
P
C
K
Site 35
T393
C
K
M
D
L
G
R
T
R
R
I
S
F
K
G
Site 36
S397
L
G
R
T
R
R
I
S
F
K
G
A
L
S
E
Site 37
T410
S
E
E
Q
M
R
E
T
S
L
G
L
L
T
G
Site 38
S411
E
E
Q
M
R
E
T
S
L
G
L
L
T
G
Y
Site 39
T495
D
Q
H
A
D
P
Q
T
S
R
S
L
L
L
L
Site 40
S498
A
D
P
Q
T
S
R
S
L
L
L
L
A
K
A
Site 41
Y571
S
A
I
V
R
E
G
Y
L
L
K
R
K
E
E
Site 42
Y592
R
F
A
F
K
K
R
Y
V
W
L
S
G
E
T
Site 43
S596
K
K
R
Y
V
W
L
S
G
E
T
L
S
F
S
Site 44
T599
Y
V
W
L
S
G
E
T
L
S
F
S
K
S
P
Site 45
S601
W
L
S
G
E
T
L
S
F
S
K
S
P
E
W
Site 46
S603
S
G
E
T
L
S
F
S
K
S
P
E
W
Q
M
Site 47
S605
E
T
L
S
F
S
K
S
P
E
W
Q
M
C
H
Site 48
Y651
T
G
A
L
H
T
T
Y
L
Q
C
K
N
V
N
Site 49
S665
N
E
L
N
Q
W
L
S
A
L
R
K
A
S
A
Site 50
S671
L
S
A
L
R
K
A
S
A
P
N
P
N
K
L
Site 51
S700
C
C
L
Q
A
E
R
S
A
A
G
C
S
R
T
Site 52
S705
E
R
S
A
A
G
C
S
R
T
H
S
A
V
T
Site 53
S709
A
G
C
S
R
T
H
S
A
V
T
L
G
D
W
Site 54
S717
A
V
T
L
G
D
W
S
D
P
L
D
P
D
A
Site 55
T728
D
P
D
A
E
A
Q
T
V
Y
R
Q
L
L
L
Site 56
S748
R
L
K
L
L
E
D
S
N
M
D
T
T
L
E
Site 57
T752
L
E
D
S
N
M
D
T
T
L
E
A
D
T
G
Site 58
T753
E
D
S
N
M
D
T
T
L
E
A
D
T
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation