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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX4
Full Name:
Sorting nexin-4
Alias:
Sorting nexin 4
Type:
Uncharacterized protein
Mass (Da):
51909
Number AA:
450
UniProt ID:
O95219
International Prot ID:
IPI00029403
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0005543
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0006897
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
A
P
L
E
P
L
G
S
P
D
A
G
L
G
A
Site 2
S43
E
G
A
G
E
E
S
S
G
V
D
T
M
T
H
Site 3
S61
W
L
K
K
I
E
I
S
V
S
E
A
E
K
R
Site 4
S63
K
K
I
E
I
S
V
S
E
A
E
K
R
T
G
Site 5
S89
A
Y
L
I
E
T
R
S
V
E
H
T
D
G
Q
Site 6
T93
E
T
R
S
V
E
H
T
D
G
Q
S
V
L
T
Site 7
S97
V
E
H
T
D
G
Q
S
V
L
T
D
S
L
W
Site 8
S102
G
Q
S
V
L
T
D
S
L
W
R
R
Y
S
E
Site 9
Y107
T
D
S
L
W
R
R
Y
S
E
F
E
L
L
R
Site 10
S108
D
S
L
W
R
R
Y
S
E
F
E
L
L
R
S
Site 11
Y116
E
F
E
L
L
R
S
Y
L
L
V
Y
Y
P
H
Site 12
Y120
L
R
S
Y
L
L
V
Y
Y
P
H
I
V
V
P
Site 13
Y121
R
S
Y
L
L
V
Y
Y
P
H
I
V
V
P
P
Site 14
T182
K
I
F
Y
L
F
L
T
Q
E
G
N
W
K
E
Site 15
T190
Q
E
G
N
W
K
E
T
V
N
E
T
G
F
Q
Site 16
S202
G
F
Q
L
K
A
D
S
R
L
K
A
L
N
A
Site 17
T210
R
L
K
A
L
N
A
T
F
R
V
K
N
P
D
Site 18
T221
K
N
P
D
K
R
F
T
D
L
K
H
Y
S
D
Site 19
S227
F
T
D
L
K
H
Y
S
D
E
L
Q
S
V
I
Site 20
S232
H
Y
S
D
E
L
Q
S
V
I
S
H
L
L
R
Site 21
Y249
A
R
V
A
D
R
L
Y
G
V
Y
K
V
H
G
Site 22
Y252
A
D
R
L
Y
G
V
Y
K
V
H
G
N
Y
G
Site 23
Y258
V
Y
K
V
H
G
N
Y
G
R
V
F
S
E
W
Site 24
S263
G
N
Y
G
R
V
F
S
E
W
S
A
I
E
K
Site 25
S266
G
R
V
F
S
E
W
S
A
I
E
K
E
M
G
Site 26
Y286
A
G
H
H
M
D
V
Y
A
S
S
I
D
D
I
Site 27
S289
H
M
D
V
Y
A
S
S
I
D
D
I
L
E
D
Site 28
Y307
Y
A
D
Q
L
K
E
Y
L
F
Y
A
E
A
L
Site 29
Y326
R
K
H
E
L
M
Q
Y
D
L
E
M
A
A
Q
Site 30
T347
Q
Q
C
E
E
L
V
T
G
T
V
R
T
F
S
Site 31
S354
T
G
T
V
R
T
F
S
L
K
G
M
T
T
K
Site 32
T367
T
K
L
F
G
Q
E
T
P
E
Q
R
E
A
R
Site 33
S391
E
G
E
Q
Q
L
K
S
K
N
L
E
G
R
E
Site 34
Y425
L
K
E
A
L
I
S
Y
A
V
M
Q
I
S
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation