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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RCBTB2
Full Name:
RCC1 and BTB domain-containing protein 2
Alias:
Chromosome condensation 1-like;RCC1-like G exchanging factor;Regulator of chromosome condensation and BTB domain-containing protein 2
Type:
Mass (Da):
60315
Number AA:
551
UniProt ID:
O95199
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
P
L
F
S
G
D
S
G
K
P
V
Q
A
T
Site 2
T19
S
G
K
P
V
Q
A
T
L
S
S
L
K
M
L
Site 3
Y60
S
A
G
N
E
V
L
Y
T
T
V
N
D
E
I
Site 4
S85
L
G
L
G
D
V
Q
S
T
I
E
P
R
R
L
Site 5
T86
G
L
G
D
V
Q
S
T
I
E
P
R
R
L
D
Site 6
S94
I
E
P
R
R
L
D
S
L
N
G
K
K
I
A
Site 7
S104
G
K
K
I
A
C
L
S
Y
G
S
G
P
H
I
Site 8
S146
G
L
V
P
C
H
I
S
T
N
L
S
N
K
Q
Site 9
Y178
G
E
V
F
A
W
G
Y
N
N
S
G
Q
V
G
Site 10
S181
F
A
W
G
Y
N
N
S
G
Q
V
G
S
G
S
Site 11
S188
S
G
Q
V
G
S
G
S
T
V
N
Q
P
I
P
Site 12
T199
Q
P
I
P
R
R
V
T
G
C
L
Q
N
K
V
Site 13
Y227
V
V
D
T
G
E
V
Y
V
W
G
Y
N
G
N
Site 14
Y231
G
E
V
Y
V
W
G
Y
N
G
N
G
Q
L
G
Site 15
S242
G
Q
L
G
L
G
N
S
G
N
Q
P
T
P
C
Site 16
T247
G
N
S
G
N
Q
P
T
P
C
R
V
A
A
L
Site 17
Y279
L
T
D
E
G
Q
V
Y
A
W
G
A
N
S
Y
Site 18
S285
V
Y
A
W
G
A
N
S
Y
G
Q
L
G
T
G
Site 19
T291
N
S
Y
G
Q
L
G
T
G
N
K
S
N
Q
S
Site 20
S295
Q
L
G
T
G
N
K
S
N
Q
S
Y
P
T
P
Site 21
Y299
G
N
K
S
N
Q
S
Y
P
T
P
V
T
V
E
Site 22
T301
K
S
N
Q
S
Y
P
T
P
V
T
V
E
K
D
Site 23
T304
Q
S
Y
P
T
P
V
T
V
E
K
D
R
I
I
Site 24
S318
I
E
I
A
A
C
H
S
T
H
T
S
A
A
K
Site 25
S322
A
C
H
S
T
H
T
S
A
A
K
T
Q
G
G
Site 26
T326
T
H
T
S
A
A
K
T
Q
G
G
H
V
Y
M
Site 27
S371
A
V
T
W
R
L
L
S
V
E
P
D
D
H
L
Site 28
T379
V
E
P
D
D
H
L
T
V
A
E
S
L
K
R
Site 29
S383
D
H
L
T
V
A
E
S
L
K
R
E
F
D
N
Site 30
T393
R
E
F
D
N
P
D
T
A
D
L
K
F
L
V
Site 31
S421
I
R
C
E
H
F
R
S
S
L
E
D
N
E
D
Site 32
S422
R
C
E
H
F
R
S
S
L
E
D
N
E
D
D
Site 33
S434
E
D
D
I
V
E
M
S
E
F
S
Y
P
V
Y
Site 34
Y441
S
E
F
S
Y
P
V
Y
R
A
F
L
E
Y
L
Site 35
S452
L
E
Y
L
Y
T
D
S
I
S
L
S
P
E
E
Site 36
S454
Y
L
Y
T
D
S
I
S
L
S
P
E
E
A
V
Site 37
S456
Y
T
D
S
I
S
L
S
P
E
E
A
V
G
L
Site 38
Y470
L
L
D
L
A
T
F
Y
R
E
N
R
L
K
K
Site 39
S541
D
L
L
K
N
F
I
S
K
A
S
R
V
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation