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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALX3
Full Name:
Homeobox protein aristaless-like 3
Alias:
Proline-rich transcription factor ALX3
Type:
Mass (Da):
36935
Number AA:
343
UniProt ID:
O95076
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
V
G
P
A
P
G
P
Y
V
A
S
G
D
E
P
Site 2
T31
E
P
P
G
P
Q
G
T
P
A
A
A
P
H
L
Site 3
T49
P
P
R
G
P
R
L
T
R
F
P
A
C
G
P
Site 4
Y71
P
A
K
P
P
A
K
Y
L
Q
D
L
G
P
G
Site 5
Y87
A
L
N
G
G
H
F
Y
E
G
P
A
E
A
E
Site 6
S98
A
E
A
E
E
K
T
S
K
A
A
S
F
P
Q
Site 7
S102
E
K
T
S
K
A
A
S
F
P
Q
L
P
L
D
Site 8
S119
G
G
P
R
D
G
P
S
N
L
Q
G
S
P
G
Site 9
S124
G
P
S
N
L
Q
G
S
P
G
P
C
L
A
S
Site 10
S137
A
S
L
H
L
P
L
S
P
G
L
P
D
S
M
Site 11
S143
L
S
P
G
L
P
D
S
M
E
L
A
K
N
K
Site 12
S151
M
E
L
A
K
N
K
S
K
K
R
R
N
R
T
Site 13
T158
S
K
K
R
R
N
R
T
T
F
S
T
F
Q
L
Site 14
T159
K
K
R
R
N
R
T
T
F
S
T
F
Q
L
E
Site 15
S161
R
R
N
R
T
T
F
S
T
F
Q
L
E
E
L
Site 16
T162
R
N
R
T
T
F
S
T
F
Q
L
E
E
L
E
Site 17
T175
L
E
K
V
F
Q
K
T
H
Y
P
D
V
Y
A
Site 18
Y177
K
V
F
Q
K
T
H
Y
P
D
V
Y
A
R
E
Site 19
Y181
K
T
H
Y
P
D
V
Y
A
R
E
Q
L
A
L
Site 20
Y214
K
W
R
K
R
E
R
Y
G
K
I
Q
E
G
R
Site 21
Y228
R
N
P
F
T
A
A
Y
D
I
S
V
L
P
R
Site 22
S231
F
T
A
A
Y
D
I
S
V
L
P
R
T
D
S
Site 23
T236
D
I
S
V
L
P
R
T
D
S
H
P
Q
L
Q
Site 24
S238
S
V
L
P
R
T
D
S
H
P
Q
L
Q
N
S
Site 25
S245
S
H
P
Q
L
Q
N
S
L
W
A
S
P
G
S
Site 26
S249
L
Q
N
S
L
W
A
S
P
G
S
G
S
P
G
Site 27
S252
S
L
W
A
S
P
G
S
G
S
P
G
G
P
C
Site 28
S254
W
A
S
P
G
S
G
S
P
G
G
P
C
L
V
Site 29
S262
P
G
G
P
C
L
V
S
P
E
G
I
P
S
P
Site 30
S268
V
S
P
E
G
I
P
S
P
C
M
S
P
Y
S
Site 31
S272
G
I
P
S
P
C
M
S
P
Y
S
H
P
H
G
Site 32
Y274
P
S
P
C
M
S
P
Y
S
H
P
H
G
S
V
Site 33
S275
S
P
C
M
S
P
Y
S
H
P
H
G
S
V
A
Site 34
S280
P
Y
S
H
P
H
G
S
V
A
G
F
M
G
V
Site 35
S299
A
A
H
P
G
I
Y
S
I
H
G
F
P
P
T
Site 36
T306
S
I
H
G
F
P
P
T
L
G
G
H
S
F
E
Site 37
S311
P
P
T
L
G
G
H
S
F
E
P
S
S
D
G
Site 38
S315
G
G
H
S
F
E
P
S
S
D
G
D
Y
K
S
Site 39
S316
G
H
S
F
E
P
S
S
D
G
D
Y
K
S
P
Site 40
Y320
E
P
S
S
D
G
D
Y
K
S
P
S
L
V
S
Site 41
S322
S
S
D
G
D
Y
K
S
P
S
L
V
S
L
R
Site 42
S324
D
G
D
Y
K
S
P
S
L
V
S
L
R
V
K
Site 43
S327
Y
K
S
P
S
L
V
S
L
R
V
K
P
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation