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Updated November 2019
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Protein Info
Short Name:
ZNF432
Full Name:
Zinc finger protein 432
Alias:
Type:
Mass (Da):
74836
Number AA:
652
UniProt ID:
O94892
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
G
P
F
Q
K
D
L
Y
R
D
V
M
L
E
I
Site 2
S46
E
I
Y
S
N
L
L
S
M
G
Y
Q
V
S
K
Site 3
Y49
S
N
L
L
S
M
G
Y
Q
V
S
K
P
D
A
Site 4
S52
L
S
M
G
Y
Q
V
S
K
P
D
A
L
S
K
Site 5
S58
V
S
K
P
D
A
L
S
K
L
E
R
G
E
E
Site 6
T68
E
R
G
E
E
P
W
T
M
E
D
E
R
H
S
Site 7
Y104
M
L
K
S
V
E
Q
Y
H
E
H
N
A
F
G
Site 8
S115
N
A
F
G
N
T
A
S
Q
T
K
S
L
C
L
Site 9
S119
N
T
A
S
Q
T
K
S
L
C
L
F
R
E
N
Site 10
T129
L
F
R
E
N
H
D
T
F
E
L
Y
I
K
T
Site 11
Y133
N
H
D
T
F
E
L
Y
I
K
T
L
K
S
N
Site 12
S139
L
Y
I
K
T
L
K
S
N
L
S
L
V
N
Q
Site 13
S142
K
T
L
K
S
N
L
S
L
V
N
Q
N
K
S
Site 14
S149
S
L
V
N
Q
N
K
S
C
E
I
N
N
S
T
Site 15
S155
K
S
C
E
I
N
N
S
T
K
F
S
G
D
G
Site 16
S159
I
N
N
S
T
K
F
S
G
D
G
K
S
F
L
Site 17
S164
K
F
S
G
D
G
K
S
F
L
H
G
N
Y
E
Site 18
Y170
K
S
F
L
H
G
N
Y
E
E
L
Y
S
A
A
Site 19
Y174
H
G
N
Y
E
E
L
Y
S
A
A
K
F
S
V
Site 20
S175
G
N
Y
E
E
L
Y
S
A
A
K
F
S
V
S
Site 21
S180
L
Y
S
A
A
K
F
S
V
S
T
K
A
N
S
Site 22
S182
S
A
A
K
F
S
V
S
T
K
A
N
S
T
K
Site 23
S187
S
V
S
T
K
A
N
S
T
K
S
Q
V
S
K
Site 24
S190
T
K
A
N
S
T
K
S
Q
V
S
K
H
Q
R
Site 25
S218
G
K
A
F
V
K
K
S
Q
L
T
D
H
E
R
Site 26
T221
F
V
K
K
S
Q
L
T
D
H
E
R
V
H
T
Site 27
T228
T
D
H
E
R
V
H
T
G
E
K
P
Y
G
C
Site 28
S246
A
K
V
F
S
R
K
S
R
L
N
E
H
Q
R
Site 29
S260
R
I
H
K
R
E
K
S
F
I
C
S
E
C
G
Site 30
S264
R
E
K
S
F
I
C
S
E
C
G
K
V
F
T
Site 31
S274
G
K
V
F
T
M
K
S
R
L
I
E
H
Q
R
Site 32
T282
R
L
I
E
H
Q
R
T
H
T
G
E
K
P
Y
Site 33
T284
I
E
H
Q
R
T
H
T
G
E
K
P
Y
I
C
Site 34
Y289
T
H
T
G
E
K
P
Y
I
C
N
E
C
G
K
Site 35
T312
I
V
H
Q
R
N
H
T
G
E
K
S
Y
I
C
Site 36
Y317
N
H
T
G
E
K
S
Y
I
C
S
E
C
G
K
Site 37
S320
G
E
K
S
Y
I
C
S
E
C
G
K
G
F
T
Site 38
S330
G
K
G
F
T
G
K
S
M
L
I
I
H
Q
R
Site 39
T338
M
L
I
I
H
Q
R
T
H
T
G
E
K
P
Y
Site 40
T340
I
I
H
Q
R
T
H
T
G
E
K
P
Y
I
C
Site 41
Y345
T
H
T
G
E
K
P
Y
I
C
S
E
C
G
K
Site 42
Y359
K
G
F
T
T
K
H
Y
V
I
I
H
Q
R
N
Site 43
T368
I
I
H
Q
R
N
H
T
G
E
K
P
Y
I
C
Site 44
Y373
N
H
T
G
E
K
P
Y
I
C
N
E
C
G
K
Site 45
T394
R
M
I
E
H
Q
R
T
H
T
G
E
K
P
Y
Site 46
S404
G
E
K
P
Y
I
C
S
E
C
G
K
G
F
P
Site 47
S414
G
K
G
F
P
R
K
S
N
L
I
V
H
Q
R
Site 48
T424
I
V
H
Q
R
N
H
T
V
E
K
S
Y
L
C
Site 49
Y429
N
H
T
V
E
K
S
Y
L
C
S
E
C
G
K
Site 50
S432
V
E
K
S
Y
L
C
S
E
C
G
K
G
F
T
Site 51
S442
G
K
G
F
T
V
K
S
M
L
I
I
H
Q
R
Site 52
T452
I
I
H
Q
R
T
H
T
G
E
K
P
Y
T
C
Site 53
Y457
T
H
T
G
E
K
P
Y
T
C
S
E
C
G
K
Site 54
T458
H
T
G
E
K
P
Y
T
C
S
E
C
G
K
G
Site 55
S460
G
E
K
P
Y
T
C
S
E
C
G
K
G
F
P
Site 56
S470
G
K
G
F
P
L
K
S
R
L
I
V
H
Q
R
Site 57
T478
R
L
I
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 58
T480
I
V
H
Q
R
T
H
T
G
E
K
P
Y
R
C
Site 59
Y485
T
H
T
G
E
K
P
Y
R
C
S
E
C
G
K
Site 60
S488
G
E
K
P
Y
R
C
S
E
C
G
K
G
F
I
Site 61
S498
G
K
G
F
I
V
N
S
G
L
M
L
H
Q
R
Site 62
T506
G
L
M
L
H
Q
R
T
H
T
G
E
K
P
Y
Site 63
T508
M
L
H
Q
R
T
H
T
G
E
K
P
Y
I
C
Site 64
S526
G
K
G
F
A
F
K
S
N
L
V
V
H
Q
R
Site 65
T534
N
L
V
V
H
Q
R
T
H
T
G
E
K
P
F
Site 66
T536
V
V
H
Q
R
T
H
T
G
E
K
P
F
M
C
Site 67
T551
S
E
C
G
K
G
F
T
M
K
R
Y
L
I
V
Site 68
Y555
K
G
F
T
M
K
R
Y
L
I
V
H
Q
Q
I
Site 69
T592
A
L
H
K
Q
V
H
T
G
E
K
P
Y
G
C
Site 70
Y597
V
H
T
G
E
K
P
Y
G
C
N
E
C
G
K
Site 71
S610
G
K
G
F
T
M
K
S
R
L
I
V
H
Q
R
Site 72
T618
R
L
I
V
H
Q
R
T
H
T
G
E
K
P
F
Site 73
T620
I
V
H
Q
R
T
H
T
G
E
K
P
F
V
C
Site 74
S628
G
E
K
P
F
V
C
S
E
C
R
K
A
F
S
Site 75
S635
S
E
C
R
K
A
F
S
S
K
R
N
L
I
V
Site 76
S636
E
C
R
K
A
F
S
S
K
R
N
L
I
V
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation