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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0776
Full Name:
E3 UFM1-protein ligase 1
Alias:
K0776
Type:
Unknown function
Mass (Da):
89595
Number AA:
794
UniProt ID:
O94874
International Prot ID:
IPI00396421
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005515
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
R
A
Q
F
A
E
A
T
Q
R
L
S
E
R
N
Site 2
S28
A
E
A
T
Q
R
L
S
E
R
N
C
I
E
I
Site 3
T50
K
Q
L
E
V
V
H
T
L
D
G
K
E
Y
I
Site 4
Y56
H
T
L
D
G
K
E
Y
I
T
P
A
Q
I
S
Site 5
T58
L
D
G
K
E
Y
I
T
P
A
Q
I
S
K
E
Site 6
S63
Y
I
T
P
A
Q
I
S
K
E
M
R
D
E
L
Site 7
S103
R
I
G
D
I
I
K
S
E
K
H
V
Q
L
V
Site 8
Y119
G
Q
L
I
D
E
N
Y
L
D
R
L
A
E
E
Site 9
T138
L
Q
E
S
G
Q
V
T
I
S
E
L
C
K
T
Site 10
S140
E
S
G
Q
V
T
I
S
E
L
C
K
T
Y
D
Site 11
T145
T
I
S
E
L
C
K
T
Y
D
L
P
G
N
F
Site 12
S166
Q
R
L
G
R
I
I
S
G
H
I
D
L
D
N
Site 13
T179
D
N
R
G
V
I
F
T
E
A
F
V
A
R
H
Site 14
S205
T
R
P
T
A
V
N
S
L
I
S
K
Y
G
F
Site 15
S208
T
A
V
N
S
L
I
S
K
Y
G
F
Q
E
Q
Site 16
T233
N
S
G
R
L
R
G
T
V
V
G
G
R
Q
D
Site 17
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Site 18
T255
I
Y
S
R
T
Q
S
T
W
V
D
S
F
F
R
Site 19
Y266
S
F
F
R
Q
N
G
Y
L
E
F
D
A
L
S
Site 20
S282
L
G
I
P
D
A
V
S
Y
I
K
K
R
Y
K
Site 21
Y283
G
I
P
D
A
V
S
Y
I
K
K
R
Y
K
T
Site 22
T290
Y
I
K
K
R
Y
K
T
T
Q
L
L
F
L
K
Site 23
S350
Q
Q
V
M
R
A
F
S
K
Q
A
S
T
V
V
Site 24
S354
R
A
F
S
K
Q
A
S
T
V
V
F
S
D
T
Site 25
T355
A
F
S
K
Q
A
S
T
V
V
F
S
D
T
V
Site 26
S405
E
E
D
L
K
Q
I
S
T
L
E
S
V
S
T
Site 27
T406
E
D
L
K
Q
I
S
T
L
E
S
V
S
T
S
Site 28
S409
K
Q
I
S
T
L
E
S
V
S
T
S
K
K
D
Site 29
S411
I
S
T
L
E
S
V
S
T
S
K
K
D
K
K
Site 30
T412
S
T
L
E
S
V
S
T
S
K
K
D
K
K
D
Site 31
S413
T
L
E
S
V
S
T
S
K
K
D
K
K
D
E
Site 32
T426
D
E
R
R
R
K
A
T
E
G
S
G
S
M
R
Site 33
S429
R
R
K
A
T
E
G
S
G
S
M
R
G
G
G
Site 34
S431
K
A
T
E
G
S
G
S
M
R
G
G
G
G
G
Site 35
Y443
G
G
G
N
A
R
E
Y
K
I
K
K
V
K
K
Site 36
S458
K
G
R
K
D
D
D
S
D
D
E
S
Q
S
S
Site 37
S462
D
D
D
S
D
D
E
S
Q
S
S
H
T
G
K
Site 38
S465
S
D
D
E
S
Q
S
S
H
T
G
K
K
K
P
Site 39
S475
G
K
K
K
P
E
I
S
F
M
F
Q
D
E
I
Site 40
Y513
I
K
P
L
N
K
T
Y
L
E
V
V
R
S
V
Site 41
T525
R
S
V
F
M
S
S
T
T
S
A
S
G
T
G
Site 42
S527
V
F
M
S
S
T
T
S
A
S
G
T
G
R
K
Site 43
T531
S
T
T
S
A
S
G
T
G
R
K
R
T
I
K
Site 44
T536
S
G
T
G
R
K
R
T
I
K
D
L
Q
E
E
Site 45
Y548
Q
E
E
V
S
N
L
Y
N
N
I
R
L
F
E
Site 46
T565
M
K
F
F
A
D
D
T
Q
A
A
L
T
K
H
Site 47
S613
E
I
R
K
K
I
L
S
K
L
S
E
E
T
K
Site 48
S629
A
L
T
K
L
H
N
S
L
N
E
K
S
I
E
Site 49
S634
H
N
S
L
N
E
K
S
I
E
D
F
I
S
C
Site 50
S640
K
S
I
E
D
F
I
S
C
L
D
S
A
A
E
Site 51
S700
L
F
Q
F
S
T
H
S
M
L
H
A
P
G
R
Site 52
S741
L
V
V
K
Q
L
V
S
Q
S
K
K
T
G
Q
Site 53
T746
L
V
S
Q
S
K
K
T
G
Q
G
D
Y
P
L
Site 54
Y751
K
K
T
G
Q
G
D
Y
P
L
N
N
E
L
D
Site 55
S766
K
E
Q
E
D
V
A
S
T
T
R
K
E
L
Q
Site 56
S776
R
K
E
L
Q
E
L
S
S
S
I
K
D
L
V
Site 57
S777
K
E
L
Q
E
L
S
S
S
I
K
D
L
V
L
Site 58
S778
E
L
Q
E
L
S
S
S
I
K
D
L
V
L
K
Site 59
S786
I
K
D
L
V
L
K
S
R
K
S
S
V
T
E
Site 60
S789
L
V
L
K
S
R
K
S
S
V
T
E
E
_
_
Site 61
S790
V
L
K
S
R
K
S
S
V
T
E
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation