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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC24D
Full Name:
Protein transport protein Sec24D
Alias:
SEC24 related gene family, member D
Type:
Golgi membrane, Membrane, Cytoplasm, Endoplasmic reticulum, Endoplasmic reticulum membrane, Golgi apparatus, COPII vesicle coat protein
Mass (Da):
113010
Number AA:
1032
UniProt ID:
O94855
International Prot ID:
IPI00747830
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030127
GO:0005789
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0006886
GO:0016044
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
S
Q
Q
G
Y
V
A
T
P
P
Y
S
Q
P
Q
Site 2
Y12
G
Y
V
A
T
P
P
Y
S
Q
P
Q
P
G
I
Site 3
S13
Y
V
A
T
P
P
Y
S
Q
P
Q
P
G
I
G
Site 4
S22
P
Q
P
G
I
G
L
S
P
P
H
Y
G
H
Y
Site 5
Y26
I
G
L
S
P
P
H
Y
G
H
Y
G
D
P
S
Site 6
Y29
S
P
P
H
Y
G
H
Y
G
D
P
S
H
T
A
Site 7
S33
Y
G
H
Y
G
D
P
S
H
T
A
S
P
T
G
Site 8
T35
H
Y
G
D
P
S
H
T
A
S
P
T
G
M
M
Site 9
S37
G
D
P
S
H
T
A
S
P
T
G
M
M
K
P
Site 10
T39
P
S
H
T
A
S
P
T
G
M
M
K
P
A
G
Site 11
Y100
V
A
S
S
H
A
P
Y
Q
P
S
A
Q
S
S
Site 12
S103
S
H
A
P
Y
Q
P
S
A
Q
S
S
Y
P
G
Site 13
S106
P
Y
Q
P
S
A
Q
S
S
Y
P
G
P
I
S
Site 14
S107
Y
Q
P
S
A
Q
S
S
Y
P
G
P
I
S
T
Site 15
Y108
Q
P
S
A
Q
S
S
Y
P
G
P
I
S
T
S
Site 16
S113
S
S
Y
P
G
P
I
S
T
S
S
V
T
Q
L
Site 17
T114
S
Y
P
G
P
I
S
T
S
S
V
T
Q
L
G
Site 18
S116
P
G
P
I
S
T
S
S
V
T
Q
L
G
S
Q
Site 19
T118
P
I
S
T
S
S
V
T
Q
L
G
S
Q
L
S
Site 20
S125
T
Q
L
G
S
Q
L
S
A
M
Q
I
N
S
Y
Site 21
S131
L
S
A
M
Q
I
N
S
Y
G
S
G
M
A
P
Site 22
Y132
S
A
M
Q
I
N
S
Y
G
S
G
M
A
P
P
Site 23
S134
M
Q
I
N
S
Y
G
S
G
M
A
P
P
S
Q
Site 24
S140
G
S
G
M
A
P
P
S
Q
G
P
P
G
P
L
Site 25
S148
Q
G
P
P
G
P
L
S
A
T
S
L
Q
T
P
Site 26
S151
P
G
P
L
S
A
T
S
L
Q
T
P
P
R
P
Site 27
T154
L
S
A
T
S
L
Q
T
P
P
R
P
P
Q
P
Site 28
S162
P
P
R
P
P
Q
P
S
I
L
Q
P
G
S
Q
Site 29
S168
P
S
I
L
Q
P
G
S
Q
V
L
P
P
P
P
Site 30
T176
Q
V
L
P
P
P
P
T
T
L
N
G
P
G
A
Site 31
T177
V
L
P
P
P
P
T
T
L
N
G
P
G
A
S
Site 32
Y191
S
P
L
P
L
P
M
Y
R
P
D
G
L
S
G
Site 33
S197
M
Y
R
P
D
G
L
S
G
P
P
P
P
N
A
Site 34
Y206
P
P
P
P
N
A
Q
Y
Q
P
P
P
L
P
G
Site 35
Y220
G
Q
T
L
G
A
G
Y
P
P
Q
Q
A
N
S
Site 36
S237
Q
M
A
G
A
Q
L
S
Y
P
G
G
F
P
G
Site 37
Y238
M
A
G
A
Q
L
S
Y
P
G
G
F
P
G
G
Site 38
S263
Q
K
K
L
D
P
D
S
I
P
S
P
I
Q
V
Site 39
S266
L
D
P
D
S
I
P
S
P
I
Q
V
I
E
N
Site 40
S277
V
I
E
N
D
R
A
S
R
G
G
Q
V
Y
A
Site 41
Y283
A
S
R
G
G
Q
V
Y
A
T
N
T
R
G
Q
Site 42
T285
R
G
G
Q
V
Y
A
T
N
T
R
G
Q
I
P
Site 43
S308
I
Q
D
Q
G
N
A
S
P
R
F
I
R
C
T
Site 44
S345
K
P
F
A
T
I
P
S
N
E
S
P
L
Y
L
Site 45
S348
A
T
I
P
S
N
E
S
P
L
Y
L
V
N
H
Site 46
Y351
P
S
N
E
S
P
L
Y
L
V
N
H
G
E
S
Site 47
Y398
V
N
D
V
P
P
F
Y
F
Q
H
L
D
H
I
Site 48
Y412
I
G
R
R
L
D
H
Y
E
K
P
E
L
S
L
Site 49
S418
H
Y
E
K
P
E
L
S
L
G
S
Y
E
Y
V
Site 50
Y422
P
E
L
S
L
G
S
Y
E
Y
V
A
T
L
D
Site 51
T427
G
S
Y
E
Y
V
A
T
L
D
Y
C
R
K
S
Site 52
Y430
E
Y
V
A
T
L
D
Y
C
R
K
S
K
P
P
Site 53
S434
T
L
D
Y
C
R
K
S
K
P
P
N
P
P
A
Site 54
T467
L
I
C
E
E
L
K
T
M
L
E
K
I
P
K
Site 55
T480
P
K
E
E
Q
E
E
T
S
A
I
R
V
G
F
Site 56
S532
F
L
V
N
Y
Q
E
S
Q
S
V
I
H
N
L
Site 57
S534
V
N
Y
Q
E
S
Q
S
V
I
H
N
L
L
D
Site 58
S550
I
P
D
M
F
A
D
S
N
E
N
E
T
V
F
Site 59
T615
K
I
L
F
Q
P
Q
T
N
V
Y
D
S
L
A
Site 60
S620
P
Q
T
N
V
Y
D
S
L
A
K
D
C
V
A
Site 61
Y659
Q
L
T
G
G
T
L
Y
K
Y
N
N
F
Q
M
Site 62
Y661
T
G
G
T
L
Y
K
Y
N
N
F
Q
M
H
L
Site 63
T695
D
A
I
M
R
V
R
T
S
T
G
F
R
A
T
Site 64
S696
A
I
M
R
V
R
T
S
T
G
F
R
A
T
D
Site 65
T697
I
M
R
V
R
T
S
T
G
F
R
A
T
D
F
Site 66
S738
F
K
H
D
D
K
L
S
E
D
S
G
A
L
I
Site 67
S770
H
N
L
G
L
N
C
S
S
Q
L
A
D
L
Y
Site 68
S771
N
L
G
L
N
C
S
S
Q
L
A
D
L
Y
K
Site 69
Y777
S
S
Q
L
A
D
L
Y
K
S
C
E
T
D
A
Site 70
S779
Q
L
A
D
L
Y
K
S
C
E
T
D
A
L
I
Site 71
S826
C
Y
R
K
N
C
A
S
P
S
A
A
S
Q
L
Site 72
S828
R
K
N
C
A
S
P
S
A
A
S
Q
L
I
L
Site 73
S857
L
K
N
C
V
L
L
S
R
P
E
I
S
T
D
Site 74
T863
L
S
R
P
E
I
S
T
D
E
R
A
Y
Q
R
Site 75
Y868
I
S
T
D
E
R
A
Y
Q
R
Q
L
V
M
T
Site 76
T875
Y
Q
R
Q
L
V
M
T
M
G
V
A
D
S
Q
Site 77
S909
L
P
A
A
V
R
C
S
E
S
R
L
S
E
E
Site 78
S914
R
C
S
E
S
R
L
S
E
E
G
I
F
L
L
Site 79
T957
A
H
I
N
T
D
M
T
L
L
P
E
V
G
N
Site 80
S967
P
E
V
G
N
P
Y
S
Q
Q
L
R
M
I
M
Site 81
Y983
I
I
Q
Q
K
R
P
Y
S
M
K
L
T
I
V
Site 82
S984
I
Q
Q
K
R
P
Y
S
M
K
L
T
I
V
K
Site 83
T988
R
P
Y
S
M
K
L
T
I
V
K
Q
R
E
Q
Site 84
Y1011
L
V
E
D
K
G
L
Y
G
G
S
S
Y
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation