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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO1D
Full Name:
Myosin-Id
Alias:
KIAA0727; myosin ID; myosin-I gamma; myr4
Type:
Motor protein
Mass (Da):
116202
Number AA:
1006
UniProt ID:
O94832
International Prot ID:
IPI00329719
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016459
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003779
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
R
F
E
K
G
R
I
Y
T
F
I
G
E
V
V
Site 2
Y52
V
V
V
S
V
N
P
Y
K
L
L
N
I
Y
G
Site 3
Y58
P
Y
K
L
L
N
I
Y
G
R
D
T
I
E
Q
Site 4
T62
L
N
I
Y
G
R
D
T
I
E
Q
Y
K
G
R
Site 5
Y66
G
R
D
T
I
E
Q
Y
K
G
R
E
L
Y
E
Site 6
Y72
Q
Y
K
G
R
E
L
Y
E
R
P
P
H
L
F
Site 7
Y86
F
A
I
A
D
A
A
Y
K
A
M
K
R
R
S
Site 8
T96
M
K
R
R
S
K
D
T
C
I
V
I
S
G
E
Site 9
S101
K
D
T
C
I
V
I
S
G
E
S
G
A
G
K
Site 10
Y114
G
K
T
E
A
S
K
Y
I
M
Q
Y
I
A
A
Site 11
S126
I
A
A
I
T
N
P
S
Q
R
A
E
V
E
R
Site 12
T153
E
A
F
G
N
A
K
T
N
R
N
D
N
S
S
Site 13
S159
K
T
N
R
N
D
N
S
S
R
F
G
K
Y
M
Site 14
S160
T
N
R
N
D
N
S
S
R
F
G
K
Y
M
D
Site 15
Y165
N
S
S
R
F
G
K
Y
M
D
I
N
F
D
F
Site 16
Y184
I
G
G
H
I
N
N
Y
L
L
E
K
S
R
V
Site 17
S189
N
N
Y
L
L
E
K
S
R
V
I
V
Q
Q
P
Site 18
S200
V
Q
Q
P
G
E
R
S
F
H
S
F
Y
Q
L
Site 19
S203
P
G
E
R
S
F
H
S
F
Y
Q
L
L
Q
G
Site 20
Y205
E
R
S
F
H
S
F
Y
Q
L
L
Q
G
G
S
Site 21
S212
Y
Q
L
L
Q
G
G
S
E
Q
M
L
R
S
L
Site 22
S218
G
S
E
Q
M
L
R
S
L
H
L
Q
K
S
L
Site 23
S224
R
S
L
H
L
Q
K
S
L
S
S
Y
N
Y
I
Site 24
S226
L
H
L
Q
K
S
L
S
S
Y
N
Y
I
H
V
Site 25
Y228
L
Q
K
S
L
S
S
Y
N
Y
I
H
V
G
A
Site 26
Y230
K
S
L
S
S
Y
N
Y
I
H
V
G
A
Q
L
Site 27
S239
H
V
G
A
Q
L
K
S
S
I
N
D
A
A
E
Site 28
T288
K
F
V
V
D
G
D
T
P
L
I
E
N
G
K
Site 29
T308
A
E
L
L
S
T
K
T
D
M
V
E
K
A
L
Site 30
Y317
M
V
E
K
A
L
L
Y
R
T
V
A
T
G
R
Site 31
T319
E
K
A
L
L
Y
R
T
V
A
T
G
R
D
I
Site 32
S337
Q
H
T
E
Q
E
A
S
Y
G
R
D
A
F
A
Site 33
Y338
H
T
E
Q
E
A
S
Y
G
R
D
A
F
A
K
Site 34
Y368
D
I
I
E
V
K
N
Y
D
T
T
I
H
G
K
Site 35
Y423
L
K
Q
E
Q
E
E
Y
Q
R
E
G
I
P
W
Site 36
Y435
I
P
W
K
H
I
D
Y
F
N
N
Q
I
I
V
Site 37
S477
M
F
L
E
A
L
N
S
K
L
G
K
H
A
H
Site 38
S486
L
G
K
H
A
H
F
S
S
R
K
L
C
A
S
Site 39
S487
G
K
H
A
H
F
S
S
R
K
L
C
A
S
D
Site 40
S493
S
S
R
K
L
C
A
S
D
K
I
L
E
F
D
Site 41
Y508
R
D
F
R
I
R
H
Y
A
G
D
V
V
Y
S
Site 42
T526
F
I
D
K
N
K
D
T
L
F
Q
D
F
K
R
Site 43
Y536
Q
D
F
K
R
L
M
Y
N
S
S
N
P
V
L
Site 44
S538
F
K
R
L
M
Y
N
S
S
N
P
V
L
K
N
Site 45
S539
K
R
L
M
Y
N
S
S
N
P
V
L
K
N
M
Site 46
S553
M
W
P
E
G
K
L
S
I
T
E
V
T
K
R
Site 47
T558
K
L
S
I
T
E
V
T
K
R
P
L
T
A
A
Site 48
T563
E
V
T
K
R
P
L
T
A
A
T
L
F
K
N
Site 49
Y585
N
L
A
S
K
E
P
Y
Y
V
R
C
I
K
P
Site 50
Y586
L
A
S
K
E
P
Y
Y
V
R
C
I
K
P
N
Site 51
S597
I
K
P
N
D
K
K
S
P
Q
I
F
D
D
E
Site 52
Y612
R
C
R
H
Q
V
E
Y
L
G
L
L
E
N
V
Site 53
T631
A
G
F
A
F
R
Q
T
Y
E
K
F
L
H
R
Site 54
Y632
G
F
A
F
R
Q
T
Y
E
K
F
L
H
R
Y
Site 55
Y639
Y
E
K
F
L
H
R
Y
K
M
I
S
E
F
T
Site 56
S654
W
P
N
H
D
L
P
S
D
K
E
A
V
K
K
Site 57
Y674
G
F
Q
D
D
V
A
Y
G
K
T
K
I
F
I
Site 58
T712
L
Q
K
V
W
R
G
T
L
A
R
M
R
Y
K
Site 59
Y718
G
T
L
A
R
M
R
Y
K
R
T
K
A
A
L
Site 60
T726
K
R
T
K
A
A
L
T
I
I
R
Y
Y
R
R
Site 61
Y730
A
A
L
T
I
I
R
Y
Y
R
R
Y
K
V
K
Site 62
Y731
A
L
T
I
I
R
Y
Y
R
R
Y
K
V
K
S
Site 63
Y734
I
I
R
Y
Y
R
R
Y
K
V
K
S
Y
I
H
Site 64
S738
Y
R
R
Y
K
V
K
S
Y
I
H
E
V
A
R
Site 65
T752
R
R
F
H
G
V
K
T
M
R
D
Y
G
K
H
Site 66
Y756
G
V
K
T
M
R
D
Y
G
K
H
V
K
W
P
Site 67
S764
G
K
H
V
K
W
P
S
P
P
K
V
L
R
R
Site 68
S786
I
F
N
R
W
R
A
S
Q
L
I
K
S
I
P
Site 69
S791
R
A
S
Q
L
I
K
S
I
P
A
S
D
L
P
Site 70
Y827
Q
R
A
W
E
G
N
Y
L
A
S
K
P
D
T
Site 71
S830
W
E
G
N
Y
L
A
S
K
P
D
T
P
Q
T
Site 72
T834
Y
L
A
S
K
P
D
T
P
Q
T
S
G
T
F
Site 73
T837
S
K
P
D
T
P
Q
T
S
G
T
F
V
P
V
Site 74
S838
K
P
D
T
P
Q
T
S
G
T
F
V
P
V
A
Site 75
T840
D
T
P
Q
T
S
G
T
F
V
P
V
A
N
E
Site 76
Y854
E
L
K
R
K
D
K
Y
M
N
V
L
F
S
C
Site 77
S870
V
R
K
V
N
R
F
S
K
V
E
D
R
A
I
Site 78
T880
E
D
R
A
I
F
V
T
D
R
H
L
Y
K
M
Site 79
Y885
F
V
T
D
R
H
L
Y
K
M
D
P
T
K
Q
Site 80
Y893
K
M
D
P
T
K
Q
Y
K
V
M
K
T
I
P
Site 81
Y902
V
M
K
T
I
P
L
Y
N
L
T
G
L
S
V
Site 82
S908
L
Y
N
L
T
G
L
S
V
S
N
G
K
D
Q
Site 83
T937
C
L
F
S
K
Q
P
T
H
E
S
R
I
G
E
Site 84
S940
S
K
Q
P
T
H
E
S
R
I
G
E
L
V
G
Site 85
S955
V
L
V
N
H
F
K
S
E
K
R
H
L
Q
V
Site 86
T978
S
L
H
G
K
K
C
T
V
S
V
E
T
R
L
Site 87
S980
H
G
K
K
C
T
V
S
V
E
T
R
L
N
Q
Site 88
T993
N
Q
P
Q
P
D
F
T
K
N
R
S
G
F
I
Site 89
S997
P
D
F
T
K
N
R
S
G
F
I
L
S
V
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation