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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINI2
Full Name:
Serpin I2
Alias:
Myoepithelium-derived serine protease inhibitor;Pancpin;Pancreas-specific protein TSA2004;Peptidase inhibitor 14
Type:
Mass (Da):
46145
Number AA:
405
UniProt ID:
O75830
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
G
S
Q
A
S
R
C
S
A
Q
K
N
T
E
F
Site 2
Y34
T
E
F
A
V
D
L
Y
Q
E
V
S
L
S
H
Site 3
S38
V
D
L
Y
Q
E
V
S
L
S
H
K
D
N
I
Site 4
S40
L
Y
Q
E
V
S
L
S
H
K
D
N
I
I
F
Site 5
T74
A
Q
Q
Q
I
R
Q
T
L
K
Q
Q
E
T
S
Site 6
S94
F
V
L
K
S
F
F
S
A
I
S
E
K
K
Q
Site 7
Y123
G
F
T
V
K
E
Q
Y
L
H
G
N
K
E
F
Site 8
S133
G
N
K
E
F
F
Q
S
A
I
K
L
V
D
F
Site 9
T152
A
C
A
E
M
I
S
T
W
V
E
R
K
T
D
Site 10
T158
S
T
W
V
E
R
K
T
D
G
K
I
K
D
M
Site 11
S167
G
K
I
K
D
M
F
S
G
E
E
F
G
P
L
Site 12
Y224
K
A
L
L
R
T
K
Y
G
Y
F
S
E
S
S
Site 13
Y226
L
L
R
T
K
Y
G
Y
F
S
E
S
S
L
N
Site 14
S228
R
T
K
Y
G
Y
F
S
E
S
S
L
N
Y
Q
Site 15
S231
Y
G
Y
F
S
E
S
S
L
N
Y
Q
V
L
E
Site 16
Y234
F
S
E
S
S
L
N
Y
Q
V
L
E
L
S
Y
Site 17
S240
N
Y
Q
V
L
E
L
S
Y
K
G
D
E
F
S
Site 18
T267
E
E
V
E
K
L
I
T
A
Q
Q
I
L
K
W
Site 19
S276
Q
Q
I
L
K
W
L
S
E
M
Q
E
E
E
V
Site 20
S286
Q
E
E
E
V
E
I
S
L
P
R
F
K
V
E
Site 21
S318
F
S
G
G
C
D
L
S
G
I
T
D
S
S
E
Site 22
Y327
I
T
D
S
S
E
V
Y
V
S
Q
V
T
Q
K
Site 23
S329
D
S
S
E
V
Y
V
S
Q
V
T
Q
K
V
F
Site 24
S344
F
E
I
N
E
D
G
S
E
A
A
T
S
T
G
Site 25
T348
E
D
G
S
E
A
A
T
S
T
G
I
H
I
P
Site 26
S349
D
G
S
E
A
A
T
S
T
G
I
H
I
P
V
Site 27
T390
I
L
F
M
G
R
V
T
N
P
D
T
Q
E
I
Site 28
T394
G
R
V
T
N
P
D
T
Q
E
I
K
G
R
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation