PhosphoNET

           
Protein Info 
   
Short Name:  GRAP2
Full Name:  GRB2-related adapter protein 2
Alias:  Adapter protein GRID; GADS; GADS protein; GRB2L; GRB-2-like protein; GRB2-related adaptor protein 2; GRBLG; GRBX; Grf40; Grf-40; Grf40 adaptor protein; Growth factor receptor binding protein; GRP2; Hematopoietic cell-associated adaptor protein GrpL; Mona; P38; SH3-SH2-SH3 adaptor Mona
Type:  Adapter/scaffold protein
Mass (Da):  37909
Number AA:  330
UniProt ID:  O75791
International Prot ID:  IPI00026928
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829     Uniprot OncoNet
Molecular Function:  GO:0005070     PhosphoSite+ KinaseNET
Biological Process:  GO:0007265  GO:0007267   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T10AVAKFDFTASGEDEL
Site 2S12AKFDFTASGEDELSF
Site 3S18ASGEDELSFHTGDVL
Site 4S29GDVLKILSNQEEWFK
Site 5Y45ELGSQEGYVPKNFID
Site 6S85GFFIIRASQSSPGDF
Site 7S88IIRASQSSPGDFSIS
Site 8S93QSSPGDFSISVRHED
Site 9S95SPGDFSISVRHEDDV
Site 10Y115MRDNKGNYFLWTEKF
Site 11T119KGNYFLWTEKFPSLN
Site 12S124LWTEKFPSLNKLVDY
Site 13Y131SLNKLVDYYRTNSIS
Site 14Y132LNKLVDYYRTNSISR
Site 15T134KLVDYYRTNSISRQK
Site 16S136VDYYRTNSISRQKQI
Site 17S138YYRTNSISRQKQIFL
Site 18T149QIFLRDRTREDQGHR
Site 19S159DQGHRGNSLDRRSQG
Site 20S164GNSLDRRSQGGPHLS
Site 21S171SQGGPHLSGAVGEEI
Site 22S181VGEEIRPSMNRKLSD
Site 23S187PSMNRKLSDHPPTLP
Site 24T192KLSDHPPTLPLQQHQ
Site 25Y207HQPQPPQYAPAPQQL
Site 26Y222QQPPQQRYLQHHHFH
Site 27S236HQERRGGSLDINDGH
Site 28T262ALMHRRHTDPVQLQA
Site 29Y280VRWARALYDFEALED
Site 30S303EVVEVLDSSNPSWWT
Site 31S304VVEVLDSSNPSWWTG
Site 32S307VLDSSNPSWWTGRLH
Site 33Y324LGLFPANYVAPMTR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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